Researchers develop new score to predict the risk of liver cancer

	Hepatology
	The latest hepatology news from News Medical

	Researchers develop new score to predict the risk of liver cancer Researchers led by Xian-Yang Qin at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan have developed a score that predicts the risk of liver cancer.

	Do cocoa flavanols influence heart and fatty liver risk factors? A recent Nutrients review examined whether cocoa-rich dark chocolate influences cardiovascular and metabolic dysfunction-associated steatotic liver disease risk factors through antioxidant, anti-inflammatory, and endothelial effects. Evidence suggests modest improvements in biomarkers, but most data come from short-term studies, so definitive clinical benefits remain unproven.

			Study reveals a new facet of how pancreatic cancer cells regulate autophagy A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a new study shows.

			Preoperative combination treatment shows promise for some patients with pancreatic cancer A new UCLA investigator-initiated study sponsored by the UCLA Health Jonsson Comprehensive Cancer Center has found that adding immunotherapy to standard chemotherapy before surgery is safe and shows promise for some patients with borderline-resectable pancreatic cancer, a disease that has historically been difficult to treat.

			Cornell study finds existing drug could boost liver cancer immunotherapy Immunotherapy – which activates the body's own immune system to kill cancer cells – has not worked well against a rare and fatal liver cancer, but a new Cornell University study finds an existing FDA-approved drug may allow the immunotherapy to fight the cancer as intended, opening the door to a potential treatment.

	Study explores whether a bidirectional causal link exists between MASLD and sarcopenia Metabolic dysfunction-associated steatotic liver disease (MASLD) and sarcopenia frequently coexist, yet their causal relationship and underlying mechanisms remain poorly defined.

	Protein made by stressed cancer cells helps tumors to evade immune attack A protein made by stressed cancer cells helps lung and pancreatic tumors evade the immune system, a new study shows.

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