Blood group A linked to a higher risk of primary biliary cholangitis

	Hepatology
	The latest hepatology news from News Medical

	Blood group A linked to a higher risk of primary biliary cholangitis Findings indicate blood group A elevates the risk of primary biliary cholangitis, suggesting ABO group analysis could aid in autoimmune liver disease diagnosis.

	Understanding thrombocytopenia in patients with portal hypertension and chronic liver disease Chronic liver disease (CLD) and its advanced stage, cirrhosis, represent a significant global health burden, with portal hypertension (PH) being a primary driver of disease progression and decompensation.

			Machine learning model boosts success of liver transplants from circulatory death donors There are more candidates on the waitlist for a liver transplant than there are available organs, yet about half the time a match is found with a donor who dies after cardiac arrest following the removal of life support, the transplant must be canceled.

			UCSF study explores sentiment analysis for hepatorenal syndrome Taking a page from market research tactics, UC San Francisco experts are studying whether artificial intelligence (AI) can improve diagnosis of a complex liver condition by using the clinical notes of multiple providers.

			Understanding leptin's dual function in MAFLD pathogenesis Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, intricately linked with obesity, type 2 diabetes (T2DM), and metabolic syndrome.

	New transplant approach resets the immune system to stop Type 1 diabetes A combination blood stem cell and pancreatic islet cell transplant from an immunologically mismatched donor completely prevented or cured Type 1 diabetes in mice in a study by Stanford Medicine researchers.

	Johns Hopkins study links mild pancreatic duct dilatation to higher cancer risk Pancreatic ductal adenocarcinoma is projected to become the second-leading cause of cancer death in the United States by 2030, according to the National Institutes of Health (NIH).

	Local anesthetic lidocaine may mitigate pancreatic cancer metastasis Pinned between the stomach and spine, the pancreas supervises both digestion and blood sugar in the body. It's also the site of an aggressive cancer called pancreatic ductal adenocarcinoma, or PDAC.

	Collaborative effort advances next-generation therapies for pancreatic and GI cancers Last year, researchers at the University of California, Riverside, developed a novel "molecular crowbar" strategy to degrade the oncogenic enzyme Pin1, a protein that is overexpressed in many tumors including pancreatic cancer.

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