Targeted therapy doubles progression-free survival in rare bile duct cancer
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 Fatty liver disease fuels aggressive metastatic colorectal cancer spreadFatty liver disease fuels aggressive metastatic colorectal cancer spread
 
Researchers at VIB and KU Leuven, with international partners, have uncovered how fatty liver disease can fuel the most aggressive form of metastatic colorectal cancer.
 
 
 Targeted therapy doubles progression-free survival in rare bile duct cancerTargeted therapy doubles progression-free survival in rare bile duct cancer
 
Results of the ongoing eNRGy trial, a single-arm, multicenter, global phase 2 clinical trial evaluating zenocutuzumab in solid tumors positive for Neuregulin 1 (NRG1) gene fusions, reported manageable side effects and clinically meaningful efficacy – including a near doubling of progression-free survival compared to expectations with standard of care – in previously treated patients with advanced NRG1-positive cholangiocarcinoma.
 
   Targeted therapy shows promise against KRAS-driven metastatic pancreatic cancerTargeted therapy shows promise against KRAS-driven metastatic pancreatic cancer
 
An investigational targeted therapy designed to block one of the most common genetic drivers of pancreatic cancer has shown promising early results when combined with standard first-line chemotherapy, according to research presented today at the ESMO Gastrointestinal Cancers Congress 2026.
 
   HonorHealth offers new drug that doubles pancreatic cancer survivalHonorHealth offers new drug that doubles pancreatic cancer survival
 
Under an FDA ruling that expands access to clinical trials, HonorHealth Research Institute is one of the first in the nation to offer a new drug, Daraxonrasib, that based on early data nearly doubles the average survival time of patients with pancreatic cancer.
 
   New study identifies potential compound for pancreatic cancer treatmentNew study identifies potential compound for pancreatic cancer treatment
 
Announcing a new article publication in BIO Integration. Fat mass and obesity-associated protein (FTO), an epitranscriptomic regulator, has been implicated in cancer progression and immune regulation but the therapeutic relevance in pancreatic cancer is unclear.
 
 New drug candidate treats severe fatty liver disease by improving gut health
 
Researchers discovered that a potential drug developed at Michigan Medicine treats severe fatty liver disease by improving gut health, according to a study published in The Journal of Clinical Investigation.
 
 
 Stem T cells replenish the immune system during chronic infections and diseases
 
Stem T cells replenish the immune system during chronic infections and diseasesT cells are an elite fighting force of the immune system, seeking out and destroying diseased cells. But in a prolonged campaign against a chronic condition - like a viral infection, or cancer - the body needs a steady supply of these killer troops. Where and how these killer troops are generated has been a mystery.
 
 
 LEF1 and niche-derived factors regulate T cell stemness across chronic diseases
 
LEF1 and niche-derived factors regulate T cell stemness across chronic diseasesT cells are an elite fighting force of the immune system, seeking out and destroying diseased cells. But in a prolonged campaign against a chronic condition - like a viral infection, or cancer - the body needs a steady supply of these killer troops.
 
 
 Microbiome science merges with oncology for better cancer treatments
 
Microbiome science merges with oncology for better cancer treatmentsCancer remains notoriously difficult to treat, partly because tumors co‑opt their surrounding environment, including the resident microbiota, to evade immune surveillance and resist conventional therapies.
 
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