| |  Current use of oral menopausal hormone therapy (commonly known as hormone replacement therapy or HRT) is associated with an increased risk of blood clots in legs / lungs regardless of dose or treatment duration, finds a large Danish study published by The BMJ today. | |
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| |  The mechanisms that cause the world's most common chronic liver disease — Metabolic dysfunction-associated steatotic liver disease (MASLD) — to develop and progress are not still fully understood. | |
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| |  New research led by Oregon Health & Science University suggests you should think twice about indulging in a late-night snack if you'd like to preserve liver health. | |
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| |  Researchers from Adelaide University have demonstrated that blocking a specific immune system gene can reduce pancreatic cancer tumor formation. | |
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| |  New research to be presented at the Annual Meeting of The European Association for the Study of Diabetes (EASD) in Milan, Italy (Sept 28 – Oct 2) and published in The Lancet Diabetes & Endocrinology shows that weekly injections with the new amylin-based obesity drug petrelintide can enable those treated to lose more than 10% of their body weight – generally lower than existing incretin-based (GLP-1 RA) drugs, but also with far fewer side effects. | |
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| |  Siemens Healthineers and Novo have announced a collaboration focused on advancing care for people living with metabolic dysfunction-associated steatotic liver disease (MASLD) and its progressive form, metabolic dysfunction-associated steatohepatitis (MASH). | |
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| |  The impact of baseline liver fibrosis severity on the effectiveness of pegylated interferon (Peg-IFN) combined with nucleos(t)ide analogs (NAs) in the treatment of hepatitis B e antigen (HBeAg)-positive chronic hepatitis B (CHB) has not been fully clarified. | |
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| |  A narrative review examined how curcumin, honey, culinary spices, and traditional remedies may influence oxidative stress, inflammation, mitochondrial function, and insulin signaling in diabetes. Although experimental research and some clinical trials suggest potential metabolic benefits, the authors emphasize that larger, well-controlled studies are needed to establish their effectiveness and safety alongside conventional treatments. | |
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| |  Research published today in Cell identifies three small subclusters of cells driving pancreatic cancer-induced cachexia, a muscle-wasting and fat-loss condition that makes patients less tolerant of cancer treatment. | |
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| |  Metabolic dysfunction-associated steatohepatitis (MASH) is often viewed through the lens of hepatic lipid accumulation, inflammation and fibrosis. A new study published in eGastroenterology shifts attention upstream, identifying intestinal neutral ceramidase as a gut-derived driver of MASH progression through its effects on microbial metabolism, epithelial signalling and intestinal barrier function. | |
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| |  The researchers first tested whether taurine could compensate for reduced intestinal taurine availability and protect against alcohol-induced liver damage. | |
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| |  Providing people with nutritious foods can improve the management of chronic metabolic diseases such as type 2 diabetes and hypertension. | |
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| |  A new study led by investigators from Mass General Brigham found routine liver cancer screening to be cost-effective and life-extending for individuals with alcohol-associated cirrhosis, even when their annual risk of developing liver cancer is less than half the risk level guiding current screening recommendations. | |
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| |  Patients preparing for pancreatic cancer surgery maintained better physical function and experienced less fatigue with five treatments of stereotactic body radiation therapy (SBRT) than with 28 treatments of conventional radiation therapy given with chemotherapy, according to a randomized phase 2 clinical trial. | |
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| |  Probiotic supplementation in very preterm infants is linked to lower rates of necrotizing enterocolitis and mortality, according to a nationwide Swedish study. | |
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| |  An analysis of nearly half a million cells from dozens of patients' tumors reveals how cancer cells continuously reshape their genetic makeup over time, enabling them to evade treatment for one of the deadliest forms of cancer. | |
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| |  Liver cancer is the fifth most commonly diagnosed cancer and the second leading cause of cancer death worldwide. Hepatocellular carcinoma (HCC) accounts for 70-85% of primary liver cancers, and its five-year recurrence rate can reach 70-80%. | |
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| |  A new review in Genes & Diseases highlights FTO, an enzyme involved in RNA modification, as a potentially important biomarker and therapeutic target across gastrointestinal cancers. | |
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| |  Pancreatic cancer remains one of the deadliest malignancies worldwide, carrying a five-year survival rate of roughly 10% and a heavy toll in disability-adjusted life years. | |
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| |  3D bioprinting improves drug screening accuracy with physiologically relevant tissue models. | |
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| |  Nutrition advice is everywhere. Eat more protein. Cut back on sugar. Get more fiber. But beneath all that advice is a surprisingly basic gap in our understanding: Scientists still have a limited view of what happens when specific nutrients reach individual cells inside the body. | |
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| |  Acute pancreatitis (AP) is one of the most common acute digestive disorders worldwide, and its most feared complication-persistent organ failure-drives mortality rates of 30% to 50%. | |
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| |  Research indicates that brief cellular reprogramming and mRNA nanoparticles can enhance liver repair, offering new strategies for acute liver injury recovery. | |
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| |  Research reveals a link between osteocalcin and insulin resistance in obese children, suggesting early metabolic changes before glucose tolerance impairment. | |
