New pathway found connecting liver congestion to fibrosis and cancer
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 How GLP-1 drugs affect the body beyond weight loss and glucose controlHow GLP-1 drugs affect the body beyond weight loss and glucose control
 
This review evaluates the safety profile of glucagon-like peptide-1 receptor agonists and related incretin therapies used for obesity and type 2 diabetes. It highlights common gastrointestinal effects, rare but debated risks, and areas where further long-term safety data are still needed.
 
 
 New pathway found connecting liver congestion to fibrosis and cancerNew pathway found connecting liver congestion to fibrosis and cancer
 
Researchers from The University of Osaka find that chronic liver congestion is linked to severe liver diseases through a specific signaling pathway in liver sinusoidal endothelial cells - key cells lining the liver's tiny blood vessels.
 
   Exerkines explained: The exercise molecules that prevent chronic diseaseExerkines explained: The exercise molecules that prevent chronic disease
 
This article examines how exercise-induced exerkines prevent disease, as well as promote metabolic, cardiovascular, immune, and neurological health.
 
   Distinct gut toxicity patterns emerge with targeted cancer treatmentsDistinct gut toxicity patterns emerge with targeted cancer treatments
 
A new paper was published in Volume 13 of Oncoscience on February 6, 2026, titled "Gastrointestinal toxicity of targeted cancer therapies in the United States: Clinicopathologic patterns, FDA safety frameworks, and implications for national patient protection."
 
   Easy-to-use blood test score can help identify alcohol-related fatty liver diseaseEasy-to-use blood test score can help identify alcohol-related fatty liver disease
 
Researchers at University of California San Diego School of Medicine have developed a new, easy-to-use blood test score that can help identify when fatty liver disease is being driven by excessive alcohol use, an important distinction that often goes unrecognized in routine care.
 
 Neem compound gedunin shows promise against pancreatic cancer
 
Neem compound gedunin shows promise against pancreatic cancerRamadevi Subramani Reddy, Ph.D., remembers the neem tree from her childhood in India - a plant her grandmother used to treat everything from fevers to infections.
 
 
 Cyborg transplants may advance cell-based therapies for diabetes
 
Cyborg transplants may advance cell-based therapies for diabetesA new electronic implant system can help lab‑grown pancreatic cells mature and function properly, potentially providing a basis for novel, cell-based therapies for diabetes.
 
 
 New review explains how circular RNAs could unlock fat browning therapies
 
New review explains how circular RNAs could unlock fat browning therapiesA Cell Death & Disease review synthesizes preclinical evidence that circular RNAs regulate adipose browning and metabolic pathways through microRNA interactions, protein binding, and organelle-linked stress mechanisms. It highlights their biomarker and therapeutic potential in obesity and type 2 diabetes while underscoring key translational challenges, including delivery specificity and human validation.
 
 
 Parental obesity before conception raises offspring fatty liver risk
 
Parental obesity before conception raises offspring fatty liver riskPre-pregnancy parental overweight and obesity is linked to the next generation's heightened risk of developing fatty liver disease, a potential precursor to cirrhosis and liver failure, suggests research published online in the journal Gut.
 
 
 Extra copies of chromosome 1q may play key role in the earliest stages of pancreatic cancer
 
Extra copies of chromosome 1q may play key role in the earliest stages of pancreatic cancerResearchers at the Johns Hopkins Kimmel Cancer Center and its Ludwig Center uncovered new evidence that extra copies of a specific chromosome segment - chromosome 1q - may play a key role in the earliest stages of pancreatic cancer development.
 
 
 Organ donation after circulatory death expands transplant opportunities
 
Organ donation after the heart stops beating, a practice called donation after circulatory death, has gone from rare to routine in the United States, a new study shows.
 
 
 ATG14 found to be a critical defender against hepatic injury and fibrosis
 
Autophagy is indispensable for maintaining hepatocyte integrity, metabolic homeostasis, and survival. While several autophagy-related proteins have been studied in hepatic physiology, the specific role of Autophagy Related 14 (ATG14) in liver health has remained unclear.
 
 
 Experts call for rapid improvements in diagnosis, treatment of bile duct cancer
 
The international group of experts, including Professor John Bridgewater (UCL Cancer Institute), is calling for rapid improvements in diagnosis, treatment and research for cholangiocarcinoma, also known as bile duct cancer.
 
 
 Study reveals pancreatic cancer's early immune evasion tactics
 
A new study suggests that pancreatic cancer may start preparing to "hide" from the immune system long before the disease becomes full-blown cancer.
 
 
 Hormone replacement therapy shows no rise in overall mortality
 
Menopausal hormone therapy (commonly known as hormone replacement therapy or HRT) is not associated with an increased risk of death, finds a Danish study of over 800,000 women published by The BMJ today.
 
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