Specific intestinal fungi play role in the pathogenesis of MASLD and cardiovascular disease

	Hepatology
	The latest hepatology news from News Medical

	Specific intestinal fungi play role in the pathogenesis of MASLD and cardiovascular disease Metabolic dysfunction-associated steatotic liver disease (MASLD) is an independent risk factor for cardiovascular disease (CVD). While gut bacteria have been linked to CVD, the role of intestinal fungi in subclinical coronary atherosclerosis (SCA) remains unclear.

	Delaying hepatitis B birth vaccines increases infant infection risks Delaying hepatitis B vaccination after birth increases infections among newborns and decreases their survival rates and quality of life, according to a new Cornell University study.

	Biliary epithelial cells found to actively prevent liver fibrosis development Many liver diseases share a common characteristic: fibrosis, that is, the progressive accumulation of scarring in the liver tissue.

	Study identifies key risk factors driving MASLD across populations Metabolic dysfunction-associated steatotic liver disease (MASLD) affects approximately 32% of the US adult population.

			Uncovering a second pathway for on-demand glycogen regulation Researchers at WEHI have uncovered a never-before-seen mechanism that human bodies utilize to control sugar. These discoveries redefine basic biological principles and pave the way for new scientific discoveries.

			Advanced heart, kidney and metabolic disease linked to higher cancer risk People with advanced heart, kidney and metabolic disease may face a higher risk of developing cancer, according to new research published today in the American Heart Association's peer-reviewed scientific journal Circulation: Population Health and Outcomes.

			AI model detects pancreatic cancer years before clinical diagnosis An AI model (REDMOD) can pick up the very early subtle tissue changes of pancreatic ductal adenocarcinoma, the most common form of pancreatic cancer, which conventional imaging and the human eye find difficult to detect, finds research published online in the journal Gut.

	Rising bowel and ovarian cancer rates in younger adults raise new concerns Cases of several cancers are rising in England among both younger and older adults, but rates of bowel and ovarian cancer are rising only among younger adults (under 50s), finds research published in the open access journal BMJ Oncology.

	Modeling the synergy of maternal screening and newborn HBV vaccination Hepatitis B virus (HBV) infection acquired at birth or during early infancy can lead to lifelong health complications, including chronic liver disease. Despite longstanding recommendations for prenatal screening, an estimated 12% to 16% of pregnant individuals in the US are not screened for hepatitis B. This gap leaves a portion of newborns at risk for undetected exposure.

	Engineered gut bacteria successfully treat metabolic drivers of liver disease When the liver fails, toxins - such as ammonia - that should be filtered from the blood build up and reach the brain.

	Microplastics in the liver may drive global liver disease rates There is considerable evidence that microplastics and nanoplastics are present in the livers of humans, and wild animal populations on land and in the ocean.

	Restoring gut microbiome may prevent liver cancer in mice Restoring the gut microbiome to its youthful state may hold the key to slowing aging and preventing liver cancer, one of the fastest-growing cancers worldwide, according to a study to be presented at Digestive Disease Week (DDW) 2026.

	Study identifies epigenetic patterns affecting insulin and glucagon production in type 2 diabetes Researchers at Lund University in Sweden have carried out the most detailed mapping to date of the epigenome in the cells that regulate the body's blood sugar levels.

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