Researchers discover molecule to fight age-related muscle decline
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 Engineered probiotic bacteria boost immune attack against pancreatic cancerEngineered probiotic bacteria boost immune attack against pancreatic cancer
 
Cancer immunotherapies have transformed treatment for many cancers, but pancreatic cancer remains especially difficult to treat. One major reason is that pancreatic tumors often create a "cold" tumor microenvironment, where the tumor prevents immune cells from mounting a strong attack.
 
 
 Researchers discover molecule to fight age-related muscle declineResearchers discover molecule to fight age-related muscle decline
 
Skeletal muscle is one of the first tissues to decline with age. This decline can lead to weakness, scarring, fat accumulation inside muscle, and the loss of fast-twitch muscle fibers that are important for quick and powerful movements.
 
   Computationally designed antibody attacks previously untreatable KRAS cancer mutationsComputationally designed antibody attacks previously untreatable KRAS cancer mutations
 
Antibodies are like "guided missiles" that find and attack cancer cells, but cancer-causing mutations inside cells have remained a "blind spot" for treatment because antibodies cannot reach them.
 
   Childhood ultra-processed food intake associates with altered insulin responsesChildhood ultra-processed food intake associates with altered insulin responses
 
Researchers analyzed dietary and metabolic data from 508 nondiabetic Mexican American children in the SAFARI family cohort, finding that higher ultra-processed food scores were associated with lower insulin sensitivity and altered early insulin secretion measures.
 
 Red meat intake emerges as a potential pancreatic cancer risk factor
 
Red meat intake emerges as a potential pancreatic cancer risk factorA systematic review and meta-analysis of 16 studies involving nearly 2 million participants found that higher red meat intake was associated with a modestly higher risk of pancreatic cancer. Processed meat intake showed no statistically significant association, although variation between studies means a small effect cannot be excluded.
 
 
 New model holds promise as a non-invasive, low-cost tool for MAFLD screening
 
New model holds promise as a non-invasive, low-cost tool for MAFLD screeningMetabolic dysfunction-associated fatty liver disease (MAFLD) represents a predominant cause of chronic liver disease, underscoring the demand for accessible, non-invasive diagnostic tools.
 
 
 Europe risks missing target to eliminate viral hepatitis by 2030
 
Europe risks missing target to eliminate viral hepatitis by 2030While Europe has made steady progress in preventing hepatitis B and C, with the prevalence of hepatitis B now at near-zero levels among children below five years old, an uneven implementation of key measures means that the region is set to miss the 2030 target to eliminate viral hepatitis as a public health threat, according to new data from the European Centre for Disease Prevention and Control (ECDC) on World Hepatitis Day.
 
 
 Lifestyle changes improve MASLD by suppressing key molecular pathway
 
Lifestyle changes improve MASLD by suppressing key molecular pathwayLifestyle modification is the cornerstone of managing metabolic dysfunction-associated steatotic liver disease (MASLD), a growing cause of chronic liver disease worldwide.
 
 
 Occult hepatitis B mutations drive liver cancer growth via Akt mTOR pathway
 
Occult hepatitis B mutations drive liver cancer growth via Akt mTOR pathwayOccult hepatitis B virus (OBI) infection presents a significant global health challenge, notoriously flying under the radar of standard viral screening while relentlessly driving the pathogenesis of hepatocellular carcinoma (HCC).
 
 
 Singing therapy provides effective relief for supragastric belching patients
 
Singing therapy provides effective relief for supragastric belching patientsA new randomized clinical trial suggests that singing therapy may provide a more effective and engaging treatment option than standard breathing exercises for people with supragastric belching, a chronic gastrointestinal disorder that can significantly affect quality of life.
 
 
 Novel interventional approach successfully treats rare hepatic myelopathy
 
Novel interventional approach successfully treats rare hepatic myelopathyHepatic myelopathy (HM) is a rare neurological complication of decompensated chronic liver disease that profoundly impairs quality of life.
 
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