| |  Researchers have identified a promising new target in the treatment of pancreatic cancer. A new study in The American Journal of Pathology, published by Elsevier, demonstrates that blocking complement factor B (CFB), a pivotal enzyme in the alternative complement pathway, halts cancer growth and alters the tumor microenvironment. | |
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| |  A family of mutations seen in about 20% of human cancers drives malignancy by changing the accessibility of genes to a particular regulatory protein, according to a study by Weill Cornell Medicine investigators. | |
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| |  The European Innovation Council (EIC) is providing approximately €3.8 million in funding for the international research project ADVANCE, in which Universitätsmedizin Frankfurt is participating. The ADVANCE research team aims to develop an mRNA-based cancer vaccine for the treatment of hepatocellular carcinoma (HCC). | |
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| |  An investigational vaccine helped the immune system recognize and respond to mutations that drive most pancreatic cancers, according to results from a randomized phase 2 clinical trial led by Mayo Clinic researchers. | |
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| |  A review on GLP-1 receptor agonists highlights risks like pancreatitis and thyroid cancer, emphasizing individual patient risk over general safety concerns. | |
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| |  Researchers developed a single-cell atlas of one million human neutrophils, identifying distinct immune cell populations and gene-expression patterns across tissues, infections, cancer, and other health conditions. Certain neutrophil signatures were associated with metabolic dysfunction, cancer outcomes, and mortality, while higher routine neutrophil counts, even within the normal range, were linked to an increased risk of chronic disease. | |
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| |  In a landmark achievement in the field of genetic medicine, researchers have reported the very first published case in a peer-reviewed journal of a successful clinical treatment of a patient with alpha-1 antitrypsin deficiency (PiZZ) using in vivo gene therapy. | |
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| |  Alcohol-related liver disease (ALD) is characterized by hepatocellular injury, oxidative stress, inflammation, and extracellular matrix remodeling, yet effective therapies remain limited. | |
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| |  The pancreas is a complex organ comprising multiple cell types that regulate blood glucose levels through hormones, such as insulin, and support digestion by producing digestive enzymes. | |
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| |  Patients assigned to receive high-dose eicosapentaenoic acid (EPA), an omega-3 fatty acid, before and after surgery for colorectal cancer liver metastases had longer overall survival than those assigned to receive placebo, according to results of the phase 3 EMT2 trial presented at the ESMO Congress 2026. | |
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| |  Pancreatic cancer is one of the most aggressive and difficult-to-treat cancers. One reason for its resistance to therapy is the dense tissue surrounding the tumor, which acts as a protective barrier and suppresses the immune response. | |
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| |  Researchers at Roswell Park Comprehensive Cancer Center have identified a promising strategy for overcoming one of the biggest challenges facing KRAS-targeted cancer therapies: treatment resistance. | |
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| |  Researchers at Weill Cornell Medicine have identified a molecular pathway that contributes to the death of insulin-producing beta cells in the pancreas. | |
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| |  Women who consume four or more alcohol drinks on a single occasion once a month or more have increased odds of advanced liver fibrosis, a new study suggests. | |
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| |  Acute recurrent pancreatitis or chronic pancreatitis can take an enormous toll on children, causing severe pain and repeated hospitalizations. | |
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| |  People with alcohol-associated liver disease who received a liver transplant survived years longer than those who did not, but there are disparities in which patients receive a transplant. | |
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| |  Hepatitis E virus (HEV) is a major cause of acute viral hepatitis, yet antiviral treatment remains largely limited to the off-label use of ribavirin. Ribavirin can cause substantial toxicity, is contraindicated during pregnancy and does not reliably benefit every patient. | |
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| |  Professor Julia Mayerle and colleagues from LMU University Hospital Munich have developed an admission-based score intended to identify pancreatitis patients more likely to be diagnosed with thrombosis during hospitalization. | |
