Common drug shows promise in preventing post-surgical liver failure
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 Natural compound puerarin may protect against cholestatic liver fibrosisNatural compound puerarin may protect against cholestatic liver fibrosis
 
A recent study published in Current Molecular Pharmacology demonstrates that puerarin-a bioactive isoflavone derived from Kudzu root and widely used in traditional Chinese medicine-may offer significant therapeutic benefits against cholestatic liver fibrosis, a progressive pathological condition arising from impaired bile formation and flow that currently lacks effective pharmacotherapies.
 
 
 Common drug shows promise in preventing post-surgical liver failureCommon drug shows promise in preventing post-surgical liver failure
 
A multi-center study, co-led by researchers at Mayo Clinic and Michigan State University, found that patients who received tranexamic acid during liver surgery were three times less likely to develop post-hepatectomy liver failure than patients who received a placebo.
 
 
 Strategic healthcare interventions bring Japan close to eliminating hepatitisStrategic healthcare interventions bring Japan close to eliminating hepatitis
 
Hepatitis B (HBV) and hepatitis C (HCV) are viral infections that can lead to health conditions such as cirrhosis, cancer, and potentially death if unmanaged. HBV can be transmitted through sexual contact, blood exposure, and mother-to-child transmission, while HCV is primarily transmitted through blood-to-blood contact.
 
   Lactate and lactylation play multifaceted roles in pancreatic ductal adenocarcinomaLactate and lactylation play multifaceted roles in pancreatic ductal adenocarcinoma
 
A comprehensive review recently published in Current Molecular Pharmacology illuminates the pivotal, multifaceted roles of lactate and its downstream protein modification, lactylation, in pancreatic ductal adenocarcinoma (PDAC).
 
   New accessible multiplex imaging workflow advances spatial liver researchNew accessible multiplex imaging workflow advances spatial liver research
 
Spatial biology technologies are reshaping modern biomedical research by enabling the visualization of cellular organization and interactions within intact tissues.
 
   Experts reframe steatotic liver disease as a dynamic continuumExperts reframe steatotic liver disease as a dynamic continuum
 
The classification of steatotic liver disease (SLD) is undergoing a major conceptual transformation. In a recent article published in eGastroenterology, Dr. Chen, Dr. Horn, and Prof.
 
 Targeting metabolic pathways could prevent relapse in KRAS-mutant cancers
 
Targeting metabolic pathways could prevent relapse in KRAS-mutant cancersOur cells rely on tightly regulated signaling pathways to control when they grow, divide, and survive. When these regulatory systems are disrupted, cells can acquire the ability to grow uncontrollably and become cancerous.
 
 
 Highly-sensitive blood test detects hidden traces of pancreatic cancer
 
Highly-sensitive blood test detects hidden traces of pancreatic cancerNorthwestern Medicine scientists have demonstrated that a highly sensitive blood test can detect traces of pancreatic cancer missed by standard testing, potentially helping physicians identify patients whose disease is more likely to return even when scans appear reassuring.
 
 
 New pathway speeds up biliary atresia diagnosis in newborns
 
New pathway speeds up biliary atresia diagnosis in newbornsBA is difficult to detect because early jaundice can resemble common newborn conditions, and pale stools may not appear immediately.
 
 
 Altering gut microbes could improve immunotherapy responses in liver cancer
 
Immune checkpoint blockade (ICB) has reshaped the treatment landscape for advanced hepatocellular carcinoma (HCC), offering new hope where few options existed.
 
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