| | New waist-to-height cut-offs to assess fat mass and obesity predicted the risk of hypertension better than body mass index, according to a new study from the University of Eastern Finland and the Robert Wood Johnson Medical School at Rutgers University in the US. | |
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| | UPMC and University of Pittsburgh clinician-scientists have weaned and kept multiple liver transplantation patients off of all immunosuppressant drugs for more than three years through a first-in-human clinical trial of a unique "immune priming" therapy. | |
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| |  Obesity trials are evolving toward chronic disease models with improved endpoints, longer study designs, and greater clinical relevance. | |
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| | UCLA researchers have identified a rogue population of immune cells that quietly accumulates in aging tissues and in the livers of people with fatty liver disease. Clearing these cells, they found, dramatically reduced inflammation and reversed liver damage in mice - even while the animals remained on an unhealthy diet. | |
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| |  A new analytical method could improve how cancer treatments are designed - by allowing scientists to track, for the first time, exactly where inside a living cell a drug accumulates. Researchers from the University of Surrey and King's College London developed the method, which detects trace amounts of metal inside individual living cells and their internal compartments without the need to kill the cells first | |
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| |  People with type 2 diabetes on a high-fat, low-carbohydrate diet may have a better chance of reversing their diabetes than those on a low-fat diet, according to a small study published in the Journal of the Endocrine Society. | |
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| |  Discover common misconceptions in renal and hepatic impairment studies and how expert teams navigate complexity in drug development. | |
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| |  Primary liver cancer continues to pose a major global health challenge, ranking as the third leading cause of cancer-related deaths worldwide. | |
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| |  Researchers found that NIH funding for major US cancers does not consistently align with lethality, with highly fatal cancers such as pancreatic cancer and small-cell lung cancer receiving far less funding per estimated death than breast or prostate cancer. The study argues that incidence alone is not enough and that funding decisions should better incorporate mortality, survival, and mortality-to-incidence ratios. | |
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| |  A new review from the Icahn School of Medicine at Mount Sinai and the Hospital Clínic de Barcelona provides one of the clearest roadmaps to date for understanding and treating liver cancer, one of the deadliest cancers worldwide. | |
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| |  See how Bambanker™ supports high post-thaw recovery and reliable downstream performance across tissues, organoids, tumor digests, and more. | |
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| |  A Neuropsychopharmacology Circumspectives article argues that cannabidiol has genuine therapeutic potential, especially in treatment-resistant pediatric epilepsy, but evidence for most other uses remains limited, heterogeneous, and not yet mature enough for broad clinical adoption. | |
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| |  Design and optimize cardiometabolic trials by addressing complexity, endpoints, recruitment, and regulatory requirements. | |
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| | When the liver is injured - for example, due to bile accumulation - immune cells become activated. In mouse experiments, the Würzburg team observed that certain immune cells undergo functional changes in response to liver damage, adopting a highly pro-inflammatory state. | |
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| | A research team led by the University of California, Irvine's Joe C. Wen School of Population & Public Health has uncovered a critical biological link explaining why individuals with metabolic dysfunction–associated steatotic liver disease (MASLD), or fatty liver disease, face significantly worse outcomes from certain foodborne infections. | |
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| | Metabolic dysfunction-associated steatotic liver disease (MASLD) has become a global public health challenge with rapidly rising prevalence, especially in China. Despite advances in treatment, the underlying molecular mechanisms remain incompletely understood. A new research article published in the Chinese Medical Journal on March 16, 2026, provides critical insights into the role of exosomal microRNAs (miRNAs) in MASLD pathogenesis. | |
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| |  In a new study published in Clinical Gastroenterology and Hepatology, the low FODMAP diet and the antibiotic rifaximin provided similar and significant relief for patients with irritable bowel syndrome with diarrhea (IBS-D). | |
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| |  In patients developing end-stage liver disease, the damage has become too severe for the liver's normally extraordinary regenerative capacity to repair or compensate for it. Once this "point of no return" has been reached, the only option is an organ transplant. | |
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| | A new update from the American Gastroenterological Association (AGA) urges stronger prevention efforts and better early-detection tools for hepatocellular carcinoma (HCC), the leading cause of cancer-related death in patients with cirrhosis, and the third most common cause of cancer-related death worldwide. | |
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| |  Explore new approaches to early-phase MASLD trials, addressing metabolic complexity and improving clinical relevance in study design. | |
