| Researchers uncover cause for progression of prostate cancer to incurable stage |
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July 27, 2018 |
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The latest prostate cancer news from News Medical |
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| |  | | |  A new study of prostate cancer in 202 men, whose cancers had spread and were resistant to standard treatment, found that a surprisingly large number of these cancers – about 17 percent – belong to a deadlier subtype of metastatic prostate cancer. | | | | |  In most cases of prostate cancer, tumor cell growth is stimulated by the action of male hormones, or androgens, such as testosterone and dihydrotestosterone (DHT).
For this to happen, these hormones have to bind to androgen receptors, proteins located mostly in the cytoplasm of prostate cells. | | | | |  Using genetic sequencing, scientists have revealed the complete DNA makeup of more than 100 aggressive prostate tumors, pinpointing important genetic errors these deadly tumors have in common. | | | | |  Androgen deprivation therapy for the treatment of prostate cancer can lead to loss of muscle and bone mass. In a recent Scandinavian Journal of Medicine & Science in Sport study of elderly patients undergoing the treatment, playing football—or what's known as soccer in the United States—over a 5-year period was linked with preserved bone mineral density (BMD) in the neck of the leg's femur. | | | | |  University of Adelaide research shows that the results of the most widely used test for prostate cancer may be affected by obesity.With increasing prevalence of obesity in high-income countries, this study published by the Society for Endocrinology, has important implications for detecting and monitoring the most common form of cancer in men. | |
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