Study links ceramide levels to prostate cancer drug response differences
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 Scientists identify new therapeutic target for deadly prostate cancerScientists identify new therapeutic target for deadly prostate cancer
 
Researchers at Columbia University Irving Medical Center have identified a gene that drives the development of neuroendocrine prostate cancer (NEPC), an aggressive form of the disease.
 
 
 Study links ceramide levels to prostate cancer drug response differencesStudy links ceramide levels to prostate cancer drug response differences
 
Ceramides-lipid molecules in cells that affect many physiological functions including cell differentiation, migration, and death-and their metabolites have been implicated in the development of cancer and other conditions.
 
   New gene expression signature may guide immunotherapy for resistant prostate cancer patientsNew gene expression signature may guide immunotherapy for resistant prostate cancer patients
 
Researchers with the James P. Allison Institute™ at The University of Texas MD Anderson Cancer Center have discovered a new gene expression signature within tumors that can help identify patients with metastatic castration-resistant prostate cancer (mCRPC) who are more likely to experience lasting benefits from combined immunotherapy treatment.
 
   Tomato-soy juice curbs inflammation in obese adultsTomato-soy juice curbs inflammation in obese adults
 
Drinking tomato-soy juice loaded with compounds shown in animal studies to promote health lowered pro-inflammatory proteins in healthy adults with obesity after four weeks, a new study found.
 
   PSMA PET detects high-risk prostate cancer bone metastasesPSMA PET detects high-risk prostate cancer bone metastases
 
Compared to conventional imaging techniques, prostate specific membrane antigen (PSMA) PET imaging provides superior detection of bone metastases in prostate cancer patients a critical indicator of a patient's long-term survival.
 
 High-risk prostate cancer patients benefit from perioperative apalutamide therapy
 
High-risk prostate cancer patients benefit from perioperative apalutamide therapyHigh-risk localized and locally advanced prostate cancer patients treated with apalutamide - a next generation neoadjuvant androgen-receptor pathway inhibitor (ARPI) - plus hormone therapy before and after prostate cancer surgery resulted in more major pathologic responses and reduced the risk of metastasis or death, meeting both primary endpoints, in an international phase 3 clinical trial led by principal investigator Mary-Ellen Taplin, MD,...
 
 
 Scientists map genetic variants behind prostate cancer therapy failure
 
Scientists map genetic variants behind prostate cancer therapy failureRecently, the research group led by Dr. Dechao Feng, Lecturer at University College London (UCL) and Distinguished Research Fellow at Zhejiang Provincial People's Hospital, published a review entitled "Intratumoral Androgens and Genetic Variants Driving Therapy Resistance in Prostate Cancer".
 
 
 Predictive model helps tailor PSMA therapy for prostate cancer patients
 
Predictive model helps tailor PSMA therapy for prostate cancer patientsA new machine-learning approach for prostate-specific membrane antigen (PSMA) treatment of metastatic castration-resistant prostate cancer (mCRPC) could estimate radiation dose to tumors and healthy organs before therapy begins.
 
 
 Study Identifies Potential Metabolic Biomarkers for Metastatic Castration-Resistant Tumors
 
Study Identifies Potential Metabolic Biomarkers for Metastatic Castration-Resistant TumorsCeramides-lipid molecules in cells that affect many physiological functions including cell differentiation, migration, and death-and their metabolites have been implicated in the development of cancer and other conditions.
 
 
 Allison Institute Platform Utilizes Spatial Profiling to Locate Protective Cellular Niches
 
Allison Institute Platform Utilizes Spatial Profiling to Locate Protective Cellular NichesResearchers with the James P. Allison Institute™ at The University of Texas MD Anderson Cancer Center have discovered a new gene expression signature within tumors that can help identify patients with metastatic castration-resistant prostate cancer (mCRPC) who are more likely to experience lasting benefits from combined immunotherapy treatment.
 
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