Researchers uncover cause for progression of prostate cancer to incurable stage
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  July 27, 2018  
  Prostate Cancer  
  The latest prostate cancer news from News Medical  
 Researchers uncover cause for progression of prostate cancer to incurable stageResearchers uncover cause for progression of prostate cancer to incurable stage
 
Researchers at the University of Oulu in Finland have discovered novel genes and mechanisms that can explain how a genomic variant in a single nucleotide polymorphism rs11672691 influences prostate cancer aggressiveness.
 
   High-fat diet and systemic inflammation contribute to progression of prostate cancerHigh-fat diet and systemic inflammation contribute to progression of prostate cancer
 
Inflammation and evasion of the immune system have been reported to be some of the new hallmarks of cancer. Notably, a high-fat diet (HFD) causes obesity and chronic inflammation, and studies conducted on mice have shown that HFD could be associated with progression and survival of prostate cancer.
 
   Study: Blood test can predict response of advanced prostate cancer patients to treatmentsStudy: Blood test can predict response of advanced prostate cancer patients to treatments
 
An international collaborative study between Lawson Health Research Institute, Memorial Sloan Kettering Cancer Center, the Royal Marsden and Epic Sciences is one of the first to demonstrate that a blood test can predict how patients with advanced prostate cancer will respond to specific treatments, leading to improved survival.
 
 Deadlier subtype of metastatic prostate cancer found to be common than previously thought
 
Deadlier subtype of metastatic prostate cancer found to be common than previously thoughtA new study of prostate cancer in 202 men, whose cancers had spread and were resistant to standard treatment, found that a surprisingly large number of these cancers – about 17 percent – belong to a deadlier subtype of metastatic prostate cancer.
 
 
 Study identifies RNA molecules that regulate male hormones in prostate cancer
 
Study identifies RNA molecules that regulate male hormones in prostate cancerIn most cases of prostate cancer, tumor cell growth is stimulated by the action of male hormones, or androgens, such as testosterone and dihydrotestosterone (DHT). For this to happen, these hormones have to bind to androgen receptors, proteins located mostly in the cytoplasm of prostate cells.
 
 
 Genetic sequencing reveals new clues to aggressiveness of prostate cancer
 
Genetic sequencing reveals new clues to aggressiveness of prostate cancerUsing genetic sequencing, scientists have revealed the complete DNA makeup of more than 100 aggressive prostate tumors, pinpointing important genetic errors these deadly tumors have in common.
 
 
 Study: Football training could improve bone mineral density in prostate cancer patients
 
Study: Football training could improve bone mineral density in prostate cancer patientsAndrogen deprivation therapy for the treatment of prostate cancer can lead to loss of muscle and bone mass. In a recent Scandinavian Journal of Medicine & Science in Sport study of elderly patients undergoing the treatment, playing football—or what's known as soccer in the United States—over a 5-year period was linked with preserved bone mineral density (BMD) in the neck of the leg's femur.
 
 
 Prostate cancer test results may be affected by obesity, shows study
 
Prostate cancer test results may be affected by obesity, shows studyUniversity of Adelaide research shows that the results of the most widely used test for prostate cancer may be affected by obesity.With increasing prevalence of obesity in high-income countries, this study published by the Society for Endocrinology, has important implications for detecting and monitoring the most common form of cancer in men.