Whole genome sequencing could help better understand genetic abnormalities underlying autism
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  October 15, 2017  
  Autism  
  The latest autism news from News Medical  
 Whole genome sequencing could help better understand genetic abnormalities underlying autismWhole genome sequencing could help better understand genetic abnormalities underlying autism
 
An analysis of the complete genomes of 2,064 people reveals that multiple genetic variations could contribute to autism. The work suggests that scanning whole genomes may one day be useful for clinical diagnostics.Autism has genetic roots, but most cases can't be explained by current genetic tests.
 
 
 Multivitamin use during pregnancy could protect children from autism with intellectual disabilitiesMultivitamin use during pregnancy could protect children from autism with intellectual disabilities
 
Children whose mothers took multivitamins during pregnancy are roughly 30 percent less likely to develop autism with a co-occurring intellectual disability, according to a new Drexel University-led study.
 
   Researchers find multiple new mutations linked to autism in children but not their parentsResearchers find multiple new mutations linked to autism in children but not their parents
 
Most cases of autism appear to be associated with the appearance of new mutations that are not inherited from the child's parents, researchers from the University of Washington School of Medicine report.
 
   Maternal immune activation linked to ASD symptom severity in children with autismMaternal immune activation linked to ASD symptom severity in children with autism
 
The retrospective cohort study of 220 Australian children, conducted between 2011-2014, indicates that a "an immune-mediated subtype" of autism driven by the body's inflammatory and immunological systems may be pivotal, according to the University of Sydney's Professor Adam Guastella.
 
   Research findings could pave way to new therapies for treating seizures and autismResearch findings could pave way to new therapies for treating seizures and autism
 
Recent research discoveries in the development of brain disorders could pave the way to new therapies for treating seizures, and even some children with autism, says a leading oncologist and researcher at the University of Alberta.
 
 Vanderbilt Center for Autism & Innovation aims to help people with ASD find meaningful employment
 
Creating a model pipeline that will assist adults on the autism spectrum find meaningful and gainful employment while enhancing local business innovation.
 
 
 Whitehead Institute scientists identify brain/body connection in genomic region linked to autism
 
Whitehead Institute scientists identify brain/body connection in genomic region linked to autismFor the first time, Whitehead Institute scientists have documented a direct link between deletions in two genes--fam57ba and doc2a--in zebrafish and certain brain and body traits, such as seizures, hyperactivity, enlarged head size, and obesity.
 
 
 Researchers improve genetic decoding of neurodevelopmental disorders
 
Researchers improve genetic decoding of neurodevelopmental disordersA result that will help in the future diagnosis of children with neurodevelopmental disorders, such as intellectual disability, autism or schizophrenia.
 
 
 Improving synchronization of brain waves enhances learning and self-control
 
Improving synchronization of brain waves enhances learning and self-controlRobert Reinhart calls the medial frontal cortex the "alarm bell of the brain." "If you make an error, this brain area fires," says Reinhart, an assistant professor of psychological and brain sciences at Boston University. "If I tell you that you make an error, it also fires.
 
 
 Scientists offer insight into how the brain makes perceptual judgments
 
Scientists offer insight into how the brain makes perceptual judgmentsScientists at Columbia's Zuckerman Institute have contributed to solving a paradox of perception, literally upending models of how the brain constructs interpretations of the outside world. When observing a scene, the brain first processes details -- spots, lines and simple shapes -- and uses that information to build internal representations of more complex objects, like cars and people.
 
 
 Researchers use mixed realty viewer to visualize complex biological networks in 3D
 
Researchers use mixed realty viewer to visualize complex biological networks in 3DThey call it the "hairy ball." It's an unflattering name for two-dimensional representations of a complex biological network, a depiction of a system of linkages and connections so complex and dense that "it looks like a big mess," said Dmitry Korkin, PhD, associate professor of computer science at Worcester Polytechnic Institute and director of the university's bioinformatics and computational biology program.
 
 
 Biased research samples can profoundly skew results of brain imaging studies
 
Biased research samples can profoundly skew results of brain imaging studiesAny scientist who studies groups of people knows that the characteristics of the "sample" -- the group of people selected for the study -- can profoundly impact the study's findings. To produce the most accurate findings, a study group ought to be as similar as possible to the people in the larger population you want to say something about.
 
 
 Researchers find surprising differences in first-ever whole-brain map of inhibitory neurons
 
Researchers find surprising differences in first-ever whole-brain map of inhibitory neuronsResearchers at Penn State College of Medicine have collaborated on the first-ever quantitative whole-brain map of inhibitory neurons in the mouse brain. These brain cells play a crucial role in regulating response to stimuli and have been widely implicated in many psychiatric conditions.
 
 
 New study maps human genome to healthy tissue functions and disease processes
 
New study maps human genome to healthy tissue functions and disease processesOur genomes help to determine who we are - the countless variations between individuals that encode the complexity of tissues and functions throughout the body.