TAAR1 mutation impairs brain signaling in schizophrenia
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 Unveiling genetic links between schizophrenia and osteoporosisUnveiling genetic links between schizophrenia and osteoporosis
 
A comprehensive genetic investigation led by Dr. Feng Liu at Tianjin Medical University General Hospital has uncovered striking molecular connections between schizophrenia and bone health, identifying 195 shared genetic loci that may explain why psychiatric patients face elevated fracture risks.
 
 
 TAAR1 mutation impairs brain signaling in schizophreniaTAAR1 mutation impairs brain signaling in schizophrenia
 
A genetic mutation passed from mother to children in families affected by schizophrenia has now been shown to completely silence a brain receptor that pharmaceutical companies are racing to target with new drugs.
 
   Large study identifies more than 100 genetic regions linked to schizophreniaLarge study identifies more than 100 genetic regions linked to schizophrenia
 
A team of researchers led by scientists from the Icahn School of Medicine at Mount Sinai, SUNY Downstate Health Sciences University, and the Department of Veterans Affairs has conducted the largest and most comprehensive genome-wide association study (GWAS) to date of schizophrenia in individuals of African ancestry.
 
   Researchers uncover unexpected role of the cerebellum in schizophrenia's negative symptomsResearchers uncover unexpected role of the cerebellum in schizophrenia's negative symptoms
 
Apathy, social withdrawal, and loss of motivation — the so-called ''negative'' symptoms of schizophrenia — are among the most disabling and hardest to treat.
 
   Alternative splicing of DOC2A gene shown to drive schizophrenia riskAlternative splicing of DOC2A gene shown to drive schizophrenia risk
 
In an important new study, Chinese researchers have discovered the previously unrecognized role of alternative splicing of the DOC2A gene in schizophrenia.
 
 Large multi-ancestry study expands understanding of schizophrenia genetics
 
Large multi-ancestry study expands understanding of schizophrenia geneticsA landmark study led by researchers with the Department of Veterans Affairs has uncovered new genetic insights into schizophrenia by analyzing data from ancestrally diverse populations, including African Americans, through the Million Veteran Program (MVP) and Cooperative Studies Program (CSP).
 
 
 Shared genetic architecture links schizophrenia with hemispheric white matter microstructure
 
Shared genetic architecture links schizophrenia with hemispheric white matter microstructureSchizophrenia is a highly heterogeneous psychiatric disorder affecting ~1% of the global population, typically emerging in adolescence or early adulthood and characterized by hallucinations, delusions, disorganized thinking, and cognitive impairments; while its etiology remains elusive, genetic factors are widely recognized as fundamental, and GWAS have identified over 200 genome-wide significant loci.
 
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