Posted in | Cell Biology

2018 Basics of Freeze Drying - Part II

2018 Basics of Freeze Drying, a four-part lecture series on basic principles and practices of lyophilization.

Lecture #2, "Physical Properties of Materials and Thermal Characterization Techniques", topics will include:

  • Physical Properties of Materials and Thermal Characterization Techniques
  • Crystalline vs. amorphous vs. mixed systems
  • Eutectic melting, glass transition, and collapse temperatures
  • Partial collapse vs. meltback
  • Examples of failed products
  • Principals of thermal analysis
  • Thermal analysis equipment and techniques: DSC, DTA, TEA
  • Freeze-dry microscopy equipment and techniques
  • Applications of thermal analysis and freeze-dry microscopy
  • Learn tips and techniques on how to freeze dry more efficiently.

Presenter

Dr. J. Jeff Schwegman, Ph.D., Founder/CEO of AB BioTechnologies

J. Jeff Schwegman, Ph.D. is currently the founder and chief executive officer of AB BioTechnologies where he specializes in speaking and consulting in parenteral pre-formulation, formulation, analytical, and lyophilization of both small molecules and large biomolecules. He is also currently the Course Director for the Center for Professional Advancement where he teaches the Lyophilization Technology course in the United States and at various locations in Europe. In addition, he holds several patents and develops new technologies in lyophilization science.

Dr. Schwegman received his BS in Biochemistry from Indiana University in 1992 and began working at Cook Imaging in Bloomington Indiana, where he gained experience in analytical, formulation and process development of parenteral products. In 1999 he began graduate study in the Department of Industrial and Physical Pharmacy at Purdue University under the direction of Dr. Steve Nail, where his focus of research involved studying changes in the physical structure of biological molecules during lyophilization.

Dr. Schwegman received his Ph.D. from Purdue University in 2003, and returned to Bloomington where he worked at Baxter Pharmaceutical Solutions as a Research Scientist in the Pharmaceutical Development group. In November 2005, he left Baxter and formed BioConvergence LLC with 3 other founders which specialized in developing new formulations and manufacturing processes for parenteral products. In February 2008, he left BioConvergence, which has become a successful company, to form AB BioTechnologies. He routinely lectures around the world on formulation, stabilization and process development of lyophilized products.

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