Posted in | Hematology

Challenges in the Emergency Department: Sepsis Redefined

Sepsis and septic shock are a daily challenge in emergency rooms and intensive care units. Despite a large number of improved therapeutic measures, sepsis is still associated with high lethality and morbidity.

Every year, up to 30 million people worldwide contract sepsis. In Germany, hospitals reported more than 175,000 sepsis diseases in 2011, of which more than 50,000 were fatal, according to the Global Sepsis Alliance (GSA) and the German Sepsis Society (DSG). Septic disease is therefore the third leading cause of death after acute myocardial infarction and causes more deaths each year than breast cancer, prostate cancer and HIV / AIDS combined.

An international task force has revised the definition of sepsis on behalf of the two leading medical societies - the European Society of Intensive Care Medicine and the (predominantly American) Society of Critical Care Medicine.

At the beginning of 2016, the Society of Critical Care Medicine's annual congress in Orlando presented the new sepsis criteria and published it simultaneously in the American Medical Journal (JAMA 2016, 315: 788-800). The focus is now on the SOFA score, which focuses on organ failure.

Sepsis is now defined as a "life-threatening organ dysfunction due to a dysregulated body response to infection". The most important change in principle is the abandonment of the SIRS criteria.

The SIRS criteria are also met for simple non-complicated infections, according to a statement of the European Society of Intensive Care Medicine. Non-infectious triggers (for example, trauma, pancreatitis, or in patients after cardiac arrest resuscitation) would also be met. On the other hand, the SIRS criteria may be absent in critically ill patients with obvious signs of life-threatening infection.

In this webinar, the challenges in emergency rooms and intensive care units will be examined in light of the new sepsis criteria. The listener should be given important information about the fastest possible diagnosis and optimal treatment of this still life-threatening disease.


Priv-Doz. Dr. med. Michael Oppert, Chief Physician of the Department of Emergency and Intensive Care Medicine, Klinikum Ernst von Bergmann non-profit GmbH

Priv-Doz. Dr. med. Michael Oppert, born in Berlin, graduated in 1995 with a Ph.D. med. and is a specialist in internal medicine with the additional designations "Special Internal Intensive Care Medicine" and "Rescue Medicine". In 2010, Dr. med. Oppert in the Department of Internal Medicine.

Since 2003, Dr. Ing. Oppert works as a senior physician in internal intensive care medicine at the University Hospital Charité, Campus Virchow-Klinikum, which includes two wards and an emergency ambulance vehicle. Since 2008, he has been responsible for the interdisciplinary intensive care unit at Campus Virchow-Klinikum as Senior Physician. He regularly drove on the ambulance of the Berlin fire department and was responsible for the preclinical care of emergency patients.

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