Abcam’s New Poster on Neuroinflammation and Alzheimer's Disease

Introduction

This poster gives a thorough overview of the interactions between microglia, astrocytes, beta amyloid (Aß), and tau that provide a deeper understanding of Alzheimer's disease.

             

Pathogenesis of Alzheimer's disease

Misfolded aggregates of tau and Aß proteins form tangles and plaques in the brain, which are a classic characterization of Alzheimer's disease. However, according to emerging evidence, neuroinflammation, which is mediated by activated glial cells, plays an important role in the pathogenesis of Alzheimer's disease.

Therefore, understanding the interactions between the immune and nervous systems may play a pivotal role in the delay or prevention of neurodegenerative diseases.

This poster gives a summary of the involvement of Aß and tau proteins in Alzheimer's disease, and demonstrates the role of astrocytes and microglia in producing an inflammatory environment.

About Abcam

Abcam is a global life sciences company providing highly validated antibodies and other binders and assays to the research and clinical communities to help advance the understanding of biology and causes of disease.

Abcam’s mission is to serve life scientists to help them achieve their mission faster by listening to their needs, continuously innovating and improving and by giving them the tools, data and experience they want. Abcam’s ambition is to become the most influential life science company for researchers worldwide.

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Last updated: Jul 14, 2018 at 6:29 PM

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