Antibody products provided by Abcam can be used to determine the extent of different post-translational modifications (PTMs) and the impact they have on p65 activation.
PTMs are known to regulate p65 activation include methylation, phosphorylation and acetylation. The below figure shows where these PTMs occur on p65, and if they enhance or repress transcriptional activity.
Figure 1. Post Transcriptional Modifications (PTMs) on p65, and the positive or negative impact they have on transcriptional activity.
Abcam provides a range of antibodies for NF-kB modification research:
Find Products for NF-kB Modification Research
Abcam is a global life sciences company providing highly validated antibodies and other binders and assays to the research and clinical communities to help advance the understanding of biology and causes of disease.
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