Kidney and Hepatic Markers

Kidney Markers

Kidneys have the ability to filter up to 220 L of blood per day while excreting urine. The filtering process is complex, yet defined: nephrons remove waste, surplus fluids, and toxins. However, they can retain proteins, minerals, and blood.

Several markers such as creatinine and glucose have been verified to diagnose renal health and pathological conditions like diabetes and chronic kidney disease. BioVision provides the most comprehensive series of research kits targeting renal markers and their products have been validated with human urine, serum, saliva, and plasma.

(A) Estimation of ACR (Cat. K551-100) in human urine in diabetic (1) and non-diabetic donors (2 and 3). For Albumin, 50 µL of undiluted samples and for Creatinine, 30 µL of diluted samples (100 times diluted using Creatinine Assay Buffer). (B) Estimation of sodium (Cat. K391-100) in human pooled serum Off-the-Clot (5 µL; 50 times diluted) and human urine (10 µL; 100 times diluted). Assays were performed following kit protocols.

Figure. (A) Estimation of ACR (Cat. K551-100) in human urine in diabetic (1) and non-diabetic donors (2 and 3). For Albumin, 50 µL of undiluted samples and for Creatinine, 30 µL of diluted samples (100 times diluted using Creatinine Assay Buffer). (B) Estimation of sodium (Cat. K391-100) in human pooled serum Off-the-Clot (5 µL; 50 times diluted) and human urine (10 µL; 100 times diluted). Assays were performed following kit protocols.

Liver Markers

The second largest organ in the human body is the liver. It weighs three pounds and has one of the most crucial functions: while producing bile acids and other blood-clotting proteins it detoxifies blood by removing chemicals, toxins, and metabolizes drugs.

A number of hepatic biomarkers like lactate dehydrogenase and alanine amino transferase have been validated for the diagnosis of pathological and physiological conditions such as hepatitis or liver damage.

 

(A) Albumin concentration in pooled human serum (PHS), fetal bovine serum (FBS), and Bovine calf serum using K554. (B). Measurement of Alanine aminotransferase activity in HepG2 cells and liver lysate using K752.

Figure. (A) Albumin concentration in pooled human serum (PHS), fetal bovine serum (FBS), and Bovine calf serum using K554. (B). Measurement of Alanine aminotransferase activity in HepG2 cells and liver lysate using K752.

BioVision Biomarkers

BioVision provides the most extensive range of research kits that target renal and hepatic markers. Products from BioVision have been validated with plasma, human serum, saliva, urine and cell and/or tissue lysates. Have a look at BioVision’s catalog and take your research to the next level.

Key Features

  • Specific, homogeneous assay
  • Versatile, non-radioactive assays (Microplate)
  • Convenient: quick protocols (<2 hours), minimal sample preparation
  • Sensitive: colorimetric/fluorometric format
  • Adaptable: operates with almost all widely available instrumentations
  • Economical: 100 assays; compatible with High Throughput Screening (HTS)

About BioVision Incorporated

BioVision, Inc., is a privately held Life Science company headquartered in the beautiful San Francisco Bay Area.

BioVision develops and offers a wide variety of products including assay kits, antibodies, recombinant proteins & enzymes, and other innovative research tools for studying Apoptosis, Metabolism, Cell Proliferation, Cellular Stress, Cell Damage and Repair, Diabetes, Obesity and Metabolic Syndrome, Stem Cell Biology, Gene Regulation, Signal Transduction, etc. BioVision's products are currently being sold in more than 60 countries worldwide.


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Last updated: Feb 21, 2020 at 9:30 AM

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