Immunohistochemistry Analysis of a Living Skin Equivalent

Labskin exhibits the immunohistochemistry markers quite similar to human skin. It is compatible with traditional cryo-sectioning preparation and paraffin wax embedding methods, as well as an extensive range of immunohistochemistry and staining protocols. (Paraffin wax embedding was the method employed to prepare all the examples.)

Labskin Structure Analysis

Basement membrane analysis

Basement membrane analysis

Barrier function analysis

Barrier function analysis

Cell proliferation analysis

Cell proliferation analysis

Labskin Microbial Response Analysis

It is possible to use Labskin within the same experimental framework to assess various endpoints at the same time. The endpoints include cytokine responses (that is, PGE2, IL-1α, IL-6, IL-8, IL-10, TNF α, etc.), photo-reactivity, wound repair, and histological changes. Endpoints such as pathogenic microorganisms and skin commensal can also be assessed.

About Labskin

At Labskin we deliver human skin microbiology services to support your product R&D activities in the cosmetic, personal care, medical device and pharmaceutical sectors. With our sector experience and use of technology, you will be accessing industry-focused services supported by world-leading skin science expertise.

Whether you need rapid, focused analysis or flexible, tailor-made research programs we can help you develop and validate skincare ingredients and products which really work.

Our skin model is a 3D human skin equivalent that incorporates vital biological components to model normal skin function.

Developed over 12 years with more than 30 scientific journal publications, it is made from young keratinocytes (human skin cells) and adult fibroblasts (metabolically-active, collagen-producing human skin cells).

“An ideal platform for basic or applied skin research, testing compounds or formulated products for the cosmetic, pharmaceutical and chemical sectors.”

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Last updated: Oct 28, 2019 at 4:42 AM


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