Antibodies News and Research

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Enhancing CAR-T cell therapy with biodegradable scaffolds

CAR-T cell therapies are transforming the treatment of previously incurable blood cancers. Six approved CAR-T products have been administered to more than 20,000 people, and more than 500 clinical trials are underway.

12 Jun 2024

First-in-human trial shows safety and efficacy of CAR T cell therapy for advanced prostate cancer

Treating prostate cancer with immunotherapy is currently difficult to do. But results from a first in-human phase 1 trial using a chimeric antigen receptor (CAR) T cell therapy developed by researchers from City of Hope, one of the largest cancer research and treatment organizations in the United States, showed that patients with advanced prostate cancer can be treated safely with the cellular immunotherapy with promising therapeutic activity, according to the phase 1 trial study published today in Nature Medicine.

12 Jun 2024

Human antibodies show promise against Black widow spider venom

There are various types of widow spiders, including black, red, and brown varieties in North and South America, the Australian redback spider, and several button spider species that inhabit South Africa.

12 Jun 2024

Study finds short-term side effects of COVID-19 mRNA vaccines boost long-term antibody response

Short-term adverse effects of COVID-19 mRNA vaccinations are linked to higher and longer-lasting neutralizing antibody responses, indicating robust immune efficacy.

11 Jun 2024

Researchers engineer water-soluble histidine kinase for enhanced antibiotic drug screens

A bacterial enzyme called histidine kinase is a promising target for new classes of antibiotics. However, it has been difficult to develop drugs that target this enzyme, because it is a "hydrophobic" protein that loses its structure once removed from its normal location in the cell membrane.

11 Jun 2024

Bird flu tests are hard to get. So how will we know when to sound the pandemic alarm?

Stanford University infectious disease doctor Abraar Karan has seen a lot of patients with runny noses, fevers, and irritated eyes lately.

11 Jun 2024

Transforming antibody drug discovery with Epitope Binning-seq

Monoclonal antibodies are crucial therapeutics due to their high specificity and binding affinity for epitopes (the precise sites where an antibody attaches itself to an antigen, triggering an immune response).

10 Jun 2024

How Epstein-Barr virus shapes immune responses in multiple sclerosis

Study found that EBV-specific immune responses in MS patients showed higher IgG titers and cell-mediated reactions to EBV antigens compared to healthy controls, suggesting a complex role of EBV in MS development.

9 Jun 2024

Doxycycline shows promise in reducing deaths and seizures from nodding syndrome

A new study suggests that a course of the drug doxycycline can decrease acute seizure-related hospitalization and deaths related to nodding syndrome.

8 Jun 2024

Curcumin-based inhibition of thiol isomerases: A potential treatment for food allergies

Clinton Mathias, associate professor of nutritional sciences in the College of Agriculture, Health and Natural Resources (CAHNR), has discovered a potential new treatment for allergic reactions.

7 Jun 2024

Gene therapy trial: restored hearing in children with hereditary deafness

The safety and effectiveness of binaural adeno-associated virus 1 (AAV1)-human otoferlin (hOTOF) therapy in five children with autosomal recessive deafness 9 (DFNB9).

7 Jun 2024

InDevR and Sino Biological team up to deliver multiplexed analytical solutions for mRNA vaccine and cell & gene therapy

InDevR, Inc., a leader in analytical solutions for vaccine in-process and quality control testing, and Sino Biological, Inc., a biotechnology company listed on the Shenzhen stock exchange subsidiary ChiNext specializing in biological research reagents and related technical contract research services, today announced a new partnership to speed development of multiplexed assays for a broad range of vaccine, mRNA therapies and cell and gene therapy applications.

From Sino Biological Inc. 7 Jun 2024

Antibodies News and Research

Enhancing CAR-T cell therapy with biodegradable scaffolds

First-in-human trial shows safety and efficacy of CAR T cell therapy for advanced prostate cancer

Human antibodies show promise against Black widow spider venom

Study finds short-term side effects of COVID-19 mRNA vaccines boost long-term antibody response

Researchers engineer water-soluble histidine kinase for enhanced antibiotic drug screens

Bird flu tests are hard to get. So how will we know when to sound the pandemic alarm?

Transforming antibody drug discovery with Epitope Binning-seq

How Epstein-Barr virus shapes immune responses in multiple sclerosis

Doxycycline shows promise in reducing deaths and seizures from nodding syndrome

Curcumin-based inhibition of thiol isomerases: A potential treatment for food allergies

Gene therapy trial: restored hearing in children with hereditary deafness

InDevR and Sino Biological team up to deliver multiplexed analytical solutions for mRNA vaccine and cell & gene therapy

‘Artificial lymph node’ shows potential to treat cancer

Ultrasound technology breaks blood-brain barrier for glioblastoma treatment

Targeting TGFβ/ROCK2/YAP signaling axis to enhance drug delivery in fibrotic pancreatic cancer

Wistar scientists develop Persistent Multivalent T Cell Engager for advanced kidney cancer

Unraveling the role of follicular helper lymphocytes in antibody production against viruses and allergies

BIOHIT HealthCare to host symposium on gastric cancer at BSG LIVE'24

IgG from long COVID patients induces specific symptoms in mice, confirming autoimmunity's role

Canagliflozin enhances senescent cell clearance, improving aging-related conditions

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