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Cognitive decline predicts driving cessation in seniors

One of the thorniest decisions facing older adults is when to give up their keys and stop driving. A new study by researchers at Washington University School of Medicine in St. Louis could provide guidance in helping seniors plan ahead.

22 May 2024

Study reveals endurance exercise's impact on the biological molecules of animals and humans

As part of an ongoing national research effort to better understand how physical activity improves health and prevents disease, seven University of Colorado Department of Medicine faculty members contributed to an article recently published in Nature, an international journal of science.

22 May 2024

Improved animal model captures full picture of periodontal disease progression

Periodontal disease, represented by periodontitis, is the leading cause of tooth loss and affects close to one in five adults worldwide.

22 May 2024

ERS Genomics and IRBM sign CRISPR/Cas9 license agreement

ERS Genomics Limited (‘ERS’), the CRISPR licensing Company, and IRBM, a leader in the field of drug discovery, today announced a non-exclusive CRISPR/Cas9 license agreement. The agreement grants IRBM access to ERS’ CRISPR/Cas9 patent portfolio.

From ERS Genomics 21 May 2024

Researchers design new regenerative medicine therapy to accelerate diabetic wound repair

Researchers at the Icahn School of Medicine at Mount Sinai have designed a regenerative medicine therapy to speed up diabetic wound repair.

20 May 2024

Transportation of cancer nanomedicines into solid tumors

A new study conducted by the Wilhelm Lab at the University of Oklahoma examines a promising development in biomedical nanoengineering.

20 May 2024

Insilico and NVIDIA unveil new LLM transformer for solving biological and chemical tasks

In a new paper, researchers from clinical stage artificial intelligence (AI)-driven drug discovery company Insilico Medicine ("Insilico"), in collaboration with NVIDIA, present a new large language model (LLM) transformer for solving biological and chemical tasks called nach0.

20 May 2024

Immune checkpoint protein VISTA can directly turn off T-cells during immunotherapy, study finds

A Cleveland Clinic-led team of scientists and physicians have discovered that the immune checkpoint protein VISTA can directly turn off tumor-fighting T-cells during immunotherapy and resist treatment.

17 May 2024

POSTECH and ImmunoBiome make significant breakthrough in the fight against cancer

A team of POSTECH and ImmunoBiome has made a significant breakthrough in the fight against cancer. Their research, published in the May issue of Nature Immunology (Volume 25, pages790–801,2024), explores a dietary-derived bacterial strain, IMB001.

17 May 2024

Genes and age reveal new insights into cognitive variability, study finds

Study examines the effects of specific genes and age on cognition, revealing potential for creating genotype- and cognition-stratified cohorts for future research.

16 May 2024

New therapy shows greater weight loss in mice by targeting brain's appetite center

A groundbreaking paper in Nature describes a promising new therapy for obesity that leads to greater weight loss in mice than existing medications.

16 May 2024

Researchers find beneficial effects of a novel drug in the management of myocardial infarction

Researchers from the Cardiac Regeneration and Heart Failure Research Group (ICREC) at the Germans Trias i Pujol Research Institute (IGTP) and the Heart Institute of the Germans Trias Hospital(iCor) have found beneficial effects of the novel drug Sacubitril/Valsartan in the management of myocardial infarction (MI).

14 May 2024

New study highlights recovery potential after traumatic brain injury

A new study in the peer-reviewed Journal of Neurotrauma found that more than 30% of patients with traumatic brain injury (TBI) for whom withdrawal of life sustaining treatment (WLST) was not performed recovered at least partial independence.

13 May 2024

New collaboration to combat river blindness and lymphatic filariasis

Prof. Achim Hoerauf, Director of the Institute of Medical Microbiology, Immunology and Parasitology at the University Hospital Bonn (UKB), and his team have succeeded in collaborating with the Department of Pharmaceutical Technology and Biopharmacy at the University of Bonn and the Helmholtz Center for Infection Research (HZI), to enter into a partnership with the Japanese pharmaceutical company Eisai for the further development of the antibiotic corallopyronin A (CorA) as a treatment for the neglected tropical diseases river blindness and lymphatic filariasis and to raise a large amount of funding.

10 May 2024

Novel bispecific antibodies show promise against evolving SARS-CoV-2 variants

Researchers developed bispecific antibodies targeting both the N-terminal and receptor binding domains of SARS-CoV-2, demonstrating significant neutralization across various Omicron variants, suggesting potential for new COVID-19 treatments.

9 May 2024

Youth-onset diabetes linked to higher Alzheimer's risk

Young people with diabetes may have a significantly higher risk of developing Alzheimer's disease later in life, according to a new study by researchers in the Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center at the University of Colorado Anschutz Medical Campus.

8 May 2024

Preclinical News and Research

Cognitive decline predicts driving cessation in seniors

Study reveals endurance exercise's impact on the biological molecules of animals and humans

Improved animal model captures full picture of periodontal disease progression

ERS Genomics and IRBM sign CRISPR/Cas9 license agreement

Researchers design new regenerative medicine therapy to accelerate diabetic wound repair

Transportation of cancer nanomedicines into solid tumors

Insilico and NVIDIA unveil new LLM transformer for solving biological and chemical tasks

Immune checkpoint protein VISTA can directly turn off T-cells during immunotherapy, study finds

POSTECH and ImmunoBiome make significant breakthrough in the fight against cancer

Genes and age reveal new insights into cognitive variability, study finds

New therapy shows greater weight loss in mice by targeting brain's appetite center

Researchers find beneficial effects of a novel drug in the management of myocardial infarction

New study highlights recovery potential after traumatic brain injury

New collaboration to combat river blindness and lymphatic filariasis

Novel bispecific antibodies show promise against evolving SARS-CoV-2 variants

Youth-onset diabetes linked to higher Alzheimer's risk

APOE4 gene linked to early onset Alzheimer's, target for therapeutic intervention

New diagnostic and treatment approach could revolutionize bladder cancer care

Innovative nanoparticle breaks blood-brain barrier to target breast cancer and brain metastases

Purdue researcher receives $2.4 million NIH grant to combat antimicrobial resistance in lung infections

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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