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New study advocates for de-escalating breast cancer surgery in women aged 55 and older

Surgery involving sentinel lymph node biopsy for middle-aged women with estrogen receptor-positive (ER+) breast cancer may do more harm than good, according to a new study led by University of Pittsburgh and UPMC Hillman Cancer Center researchers.

22 May 2024

Study reveals ferroptosis as a major driver of severe COVID-19 lung damage

Ferroptosis, an iron-dependent cell death mechanism, is identified as a key factor in severe COVID-19 lung disease, suggesting potential new therapeutic targets.

22 May 2024

Dupilumab shows promise in cutting COPD flare-ups and boosting lung function

Dupilumab significantly reduces exacerbations and improves lung function in COPD patients with elevated eosinophil counts, confirming the efficacy of targeting type 2 inflammation.

22 May 2024

Sharp uptick in youth using wegovy and ozempic, study reports

Public interest in weight loss drugs like Wegovy and Ozempic is surging, but national data on dispensing patterns in the United States are surprisingly scarce.

22 May 2024

Improved animal model captures full picture of periodontal disease progression

Periodontal disease, represented by periodontitis, is the leading cause of tooth loss and affects close to one in five adults worldwide.

22 May 2024

Lemon verbena extract boosts sleep quality

Researchers explore the utility of lemon verbena in improving the sleep of individuals with poor sleep.

22 May 2024

Key studies on GLP-1 drugs, alpha-gal syndrome, and liver disease medications to be presented at DDW 2024

Studies examining the risks of GLP-1 weight-loss drugs, distinguishing alpha-gal syndrome from other GI disorders, and comparing medications to slow the progression of liver disease in patients with alcohol-use disorder will be presented this week at Digestive Disease Week (DDW) 2024.

21 May 2024

Study offers new insights into how ketamine works

A World Health Organization Essential Medicine, ketamine is widely used at varying doses for sedation, pain control, general anesthesia and as a therapy for treatment-resistant depression.

21 May 2024

Taurine supplementation shows promise in reducing metabolic syndrome risk factors, study finds

A study in Nutrition & Diabetes meta-analyzed randomized clinical trials and found that taurine supplementation significantly reduces key risk factors for metabolic syndrome, such as high blood pressure, fasting blood glucose, and triglycerides, with no notable adverse effects.

20 May 2024

Ketogenic diets linked to cellular aging in vital organs, new study finds

Study reveals that ketogenic diets induce cellular senescence in mice, affecting organs like the kidneys and heart through AMPK and p53 pathways. These findings highlight potential long-term risks associated with ketogenic diets.

20 May 2024

Treating obesity using glucagon-like peptide-1-directed N-methyl-D-aspartate receptor inhibition

Bimodal drug that successfully cures obesity, hyperglycemia, and dyslipidemia in mouse models.

20 May 2024

Diet and nutrition's influence on acne vulgaris

Study highlights the significant role of certain dietary components, such as dairy, chocolate, and fats, in the development of acne vulgaris and underscores the need for further research to inform effective dietary recommendations.

19 May 2024

Comprehensive cost and utilization of commercial CAR-T therapy in pediatric B-ALL patients

A new editorial paper was published in Oncoscience (Volume 11) on April 25, 2024, entitled, "The price of hope: CAR-T therapy in pediatric leukemia."

17 May 2024

Monell study uncovers dual role of mammalian sweet taste receptor in regulating blood sugar levels

The rich research portfolio of the Monell Chemical Senses Center on sweet taste goes way back: Monell scientists were one of four teams in 2001 that found and described the mammalian sweet taste receptor – TAS1R2-TAS1R3.

17 May 2024

Immune checkpoint protein VISTA can directly turn off T-cells during immunotherapy, study finds

A Cleveland Clinic-led team of scientists and physicians have discovered that the immune checkpoint protein VISTA can directly turn off tumor-fighting T-cells during immunotherapy and resist treatment.

17 May 2024

Novel gene-delivery vehicle shows promise for treating brain disorders

In an important step toward more effective gene therapies for brain diseases, researchers from the Broad Institute of MIT and Harvard have engineered a gene-delivery vehicle that uses a human protein to efficiently cross the blood-brain barrier and deliver a disease-relevant gene to the brain in mice expressing the human protein.

16 May 2024

Receptor News and Research

New study advocates for de-escalating breast cancer surgery in women aged 55 and older

Study reveals ferroptosis as a major driver of severe COVID-19 lung damage

Dupilumab shows promise in cutting COPD flare-ups and boosting lung function

Sharp uptick in youth using wegovy and ozempic, study reports

Improved animal model captures full picture of periodontal disease progression

Lemon verbena extract boosts sleep quality

Key studies on GLP-1 drugs, alpha-gal syndrome, and liver disease medications to be presented at DDW 2024

Study offers new insights into how ketamine works

Taurine supplementation shows promise in reducing metabolic syndrome risk factors, study finds

Ketogenic diets linked to cellular aging in vital organs, new study finds

Treating obesity using glucagon-like peptide-1-directed N-methyl-D-aspartate receptor inhibition

Diet and nutrition's influence on acne vulgaris

Comprehensive cost and utilization of commercial CAR-T therapy in pediatric B-ALL patients

Monell study uncovers dual role of mammalian sweet taste receptor in regulating blood sugar levels

Immune checkpoint protein VISTA can directly turn off T-cells during immunotherapy, study finds

Novel gene-delivery vehicle shows promise for treating brain disorders

Research highlights complexity of xylazine and fentanyl combination in overdose cases

New therapy shows greater weight loss in mice by targeting brain's appetite center

Repurposing human-approved drugs for prion disease treatment

COVID-19 linked to rise in autoimmune lung disease, study finds

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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