Gene Editing News and Research

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Scientists unlock mystery behind a deadly strain of cholera bacteria

A deadly strain of cholera bacteria that emerged in Indonesia back in 1961 continues to spread widely to this day, claiming thousands of lives around the world every year, sickening millions -; and, with its persistence, baffling scientists.

14 May 2024

ERS Genomics appoints John E Milad as Chief Executive Officer

ERS Genomics Limited (‘ERS’), the CRISPR licensing company, today announced the appointment of John E Milad as CEO, with immediate effect. John brings over 25 years of experience as an executive leader, venture capitalist, and investment banker focused on the life sciences and medical technology sectors.

From ERS Genomics 13 May 2024

Genetic variant increases heart failure risk and decreases longevity in Black Americans

Researchers at Brigham and Women’s Hospital and Duke University showed that a genetic variant, present in 3-4% of self-identified Black individuals in the U.S., increases the risk for both heart failure and death and contributes to significant decreases in longevity at the population level.

11 May 2024

Broken String Biosciences and the Francis Crick Institute collaborate to advance ALS research

Partnership to expand applications of DNA break-mapping technology and advance understanding of genomic instability in development of the neurodegenerative disease amyotrophic lateral sclerosis.

From Broken String Biosciences 7 May 2024

CRISPR-based gene editing shows promise in treating rare form of blindness

About 79% of clinical trial participants experienced measurable improvement after receiving experimental, CRISPR-based gene editing that is designed to fix a rare form of blindness, according to a paper published in the New England Journal of Medicine.

6 May 2024

MedStar Washington Hospital Center enrolls first U.S. patient in gene-editing therapy trial for heart disease

The first U.S. heart patient involved in a study for a new gene-editing therapy directly infused inside the body has successfully been enrolled at MedStar Washington Hospital Center.

6 May 2024

CRISPR gene editing shows promise for treating individuals with a form of inherited blindness

Results from a groundbreaking clinical trial of CRISPR gene editing in 14 individuals with a form of inherited blindness show that the treatment is safe and led to measurable improvements in 11 of the participants treated.

6 May 2024

New vaccine approach shows promise in targeting less variable region of influenza virus

Duke researchers have opened a new avenue in the attack against influenza viruses by creating a vaccine that encourages the immune system to target a portion of the virus surface that is less variable.

2 May 2024

Targeted nanoparticle delivery of FZD4 decreases lung tumor growth and metastasis

A recent breakthrough study from the lab of Tanya Kalin, MD, PhD, professor of Child Health and Internal Medicine at the University of Arizona College of Medicine – Phoenix, has shown potential to improve therapeutic outcomes for patients suffering from lung cancers.

16 Apr 2024

Gene defect associated with argininosuccinic aciduria corrected using CRISPR-Cas9 technique

Argininosuccinate lyase deficiency (ASLD), also known as argininosuccinic aciduria, is a disease that has been enriched in the Finnish genetic heritage.

4 Apr 2024

Boosting mRNA activity and longevity with multi-tailed structures

Messenger RNA (mRNA) made its big leap into the public limelight during the pandemic, thanks to its cornerstone role in several COVID-19 vaccines

22 Mar 2024

New “GPS nanoparticle” delivers a genetic punch to the protein implicated in tumor spread

A newly developed "GPS nanoparticle" injected intravenously can home in on cancer cells to deliver a genetic punch to the protein implicated in tumor growth and spread, according to researchers from Penn State.

11 Mar 2024

Scientists develop robust iPSC-derived rejuvenated T lymphocytes for cervical cancer treatment

Cervical cancer is among the most common malignancies affecting women worldwide. In 2020 alone, approximately 600,000 women were diagnosed with this disease, and over 314,000 died from it.

5 Mar 2024

New scSNV-seq technique unveils genetic drivers of diseases like cancer and Alzheimer's

Scientists have developed a new screening tool to uncover how genetic changes affect gene activity and can lead to diseases such as cancer, autoimmunity, neurodegeneration and cardiovascular disease. This new tool enables the investigation of thousands of DNA mutations identified by genetic studies in one experiment, guiding the development of advanced diagnostics and treatments.

4 Mar 2024

Breakthrough CRISPR technique unlocks insights about cancer immunology

Over the past two decades, the immune system has attracted increasing attention for its role in fighting cancer.

29 Feb 2024

Husker research duo selected as Phase 1 winners in the NIH's Targeted Genome Editor Delivery Challenge

A Husker research duo was named a first-round winner in a National Institutes of Health competition aimed at generating solutions for delivering genome-editing technology to the cells of people with rare and common diseases.

19 Feb 2024

Research demonstrates a bat species' resistance to cancer, pinpoints key genes

A study reveals Myotis pilosus bats exhibit exceptional cancer resistance through gene downregulation, offering insights into natural anticancer mechanisms.

18 Feb 2024

ANU discovery provides new insight into how the immune system fights malaria

Researchers from The Australian National University (ANU) have discovered a previously unknown ability of a group of immune system cells, known as Atypical B cells (ABCs), to fight infectious diseases such as malaria.

8 Feb 2024

CRISPR-Cas9 gene-editing tool repairs defective T cells to treat rare hereditary disease

Some hereditary genetic defects cause an exaggerated immune response that can be fatal. Using the CRISPR-Cas9 gene-editing tool, such defects can be corrected, thus normalizing the immune response, as researchers led by Klaus Rajewsky from the Max Delbrück Center now report in "Science Immunology."

2 Feb 2024

Breakthrough gene-editing therapy transforms lives of patients with a hereditary disorder

A group of patients with a hereditary disorder have had their lives transformed by a single treatment of a breakthrough gene-editing therapy, according to the lead researcher.

2 Feb 2024

Gene Editing News and Research

Scientists unlock mystery behind a deadly strain of cholera bacteria

ERS Genomics appoints John E Milad as Chief Executive Officer

Genetic variant increases heart failure risk and decreases longevity in Black Americans

Broken String Biosciences and the Francis Crick Institute collaborate to advance ALS research

CRISPR-based gene editing shows promise in treating rare form of blindness

MedStar Washington Hospital Center enrolls first U.S. patient in gene-editing therapy trial for heart disease

CRISPR gene editing shows promise for treating individuals with a form of inherited blindness

New vaccine approach shows promise in targeting less variable region of influenza virus

Targeted nanoparticle delivery of FZD4 decreases lung tumor growth and metastasis

Gene defect associated with argininosuccinic aciduria corrected using CRISPR-Cas9 technique

Boosting mRNA activity and longevity with multi-tailed structures

New “GPS nanoparticle” delivers a genetic punch to the protein implicated in tumor spread

Scientists develop robust iPSC-derived rejuvenated T lymphocytes for cervical cancer treatment

New scSNV-seq technique unveils genetic drivers of diseases like cancer and Alzheimer's

Breakthrough CRISPR technique unlocks insights about cancer immunology

Husker research duo selected as Phase 1 winners in the NIH's Targeted Genome Editor Delivery Challenge

Research demonstrates a bat species' resistance to cancer, pinpoints key genes

ANU discovery provides new insight into how the immune system fights malaria

CRISPR-Cas9 gene-editing tool repairs defective T cells to treat rare hereditary disease

Breakthrough gene-editing therapy transforms lives of patients with a hereditary disorder

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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