Parkinson's Disease

This hub offers a comprehensive exploration of Parkinson’s disease, integrating the latest scientific understanding, clinical practice, and emerging research. The linked articles cover the fundamentals of Parkinson’s disease pathophysiology, diagnosis, treatment strategies, and prognosis, while also examining associated conditions, genetic factors, and disease-modifying therapies. Readers will find evidence-based guidance on symptom management, including motor and non-motor features, along with in-depth discussions on neuroprotective interventions, the gut-brain axis, and the role of comorbidities. The collection also addresses the psychosocial impact of Parkinson’s disease, support resources, and advances in experimental therapies. Whether you are a healthcare professional, researcher, patient, or caregiver, these resources provide authoritative insights into the complex landscape of Parkinson’s disease.

Does Exercise Slow Parkinson's Disease Progression?

A growing pool of evidence suggests that high-intensity physical exercise may have beneficial outcomes in PD patients.

Bipolar Disorder and Parkinson’s

VPS35 Gene and Parkinson's Disease

Uncovering Hidden Symptoms: Hallucinations and Delusions in Parkinson’s Disease

Parkinson's Disease History

Is Appendectomy Linked to Parkinson’s Disease?

Do Antioxidants Benefit Patients with Alzheimer’s and Parkinson’s?

Parkinson's Disease Pathophysiology

Developing Drugs for Neurodegenerative Diseases

Parkinson's Disease Research

Parkinson’s Disease and Sleeping Disorders

Mythbusting: Misconceptions surrounding Parkinson’s Disease

See more featured articles »

Neurophysiotherapy for Parkinson's Disease

Herpes Virus and Parkinson's Disease

Human brain may stay active for hours after death

Parkinson's Disease Prognosis

Thalamotomy, Pallidotomy and Subthalamotomy

Parkinson's Disease Diagnosis

Where Does Parkinson’s Disease Originate?

Parkinson's Disease Treatment

Parkinsonism in Spinocerebellar Ataxia

Parkinson's Disease and Helicobacter Pylori

Parkinson's Compared to Dementia with Lewy Bodies (DLB)

Gut Bacteria Affecting Parkinson’s Treatment

Estrogen as a Treatment for Parkinson’s Disease

Progressive Supranuclear Palsy (PSP) Versus Parkinson's Disease

Parkinson's Disease Support

Parkinson's Disease and the Gut Microbiome

Identifying Early Symptoms in Parkinson’s

Impact of COVID-19 on Parkinson's Disease

Gut-Brain Axis and Neurodegenerative Disorders

Gene Therapies for Parkinson’s Disease

Physiotherapy for Parkinson's Disease

What is Parkinson's Disease?

Latest Parkinson's Disease News and Research

Stem cell implants aim to restore dopamine in Parkinson’s disease

Parkinson's disease is a progressive neurodegenerative disorder that affects more than one million people in the United States, with approximately 90,000 new cases diagnosed each year.

5 Feb 2026

Brain network discovery opens new path for Parkinson’s treatment

Parkinson's disease, a progressive neurological disorder affecting more than 1 million people in the U.S. and more than 10 million globally, is characterized by debilitating symptoms such as tremors, movement difficulties, sleep disturbances and cognitive impairments.

4 Feb 2026

Study identifies brain region driving one-shot visual learning

Despite decades of research, the mechanisms behind fast flashes of insight that change how a person perceives their world, termed "one-shot learning," have remained unknown.

4 Feb 2026

Playing pink noise during sleep could be harmful for children

Pink noise-often used to promote sleep-may reduce restorative REM sleep and interfere with sleep recovery.

2 Feb 2026

Regulating microglial phagocytosis through immunotherapy could slow Parkinson's disease progression

By analyzing tissue from patients with Parkinson's disease, and animal and cellular models of the disease, a research team from the Institut de Neurociències of the UAB has shown that the main immune cells of the brain become reactive and overexpress certain receptors that promote the elimination of dopaminergic neurons, even when these neurons are still functional.

2 Feb 2026

Distinct tau chemical signatures redefine diagnosis across neurodegenerative diseases

Tau protein aggregation is a shared feature in over 20 neurodegenerative diseases (collectively referred to as "tauopathies"). New research led by Boston Children's Hospital challenges the current "one-size-fits-all" approach to diagnosing and treating these tauopathies.

31 Jan 2026

New wearable device may reduce hand tremors linked with neurological conditions

UBC Okanagan researchers have advanced their work on developing a non-invasive, accessible way to reduce uncontrolled hand tremors.

30 Jan 2026

Biomarker discovery may pave the way for early diagnosis of Parkinson's

A team led by researchers at Chalmers University of Technology, Sweden, has succeeded in identifying biomarkers for Parkinson's disease in its earliest stages, before extensive brain damage has occurred.

29 Jan 2026

BU receives $2M grant to study MedRhythms' MOVIVE device for Parkinson's gait

Boston University (BU) today announced it has been awarded a $2 million research grant from The Michael J. Fox Foundation for Parkinson's Research (MJFF).

27 Jan 2026

New atlas of brain lysosomes sheds light on neurodegenerative disorders

Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when the cellular sanitation machines responsible for those tasks, called lysosomes, break down or get overwhelmed, it can increase the risk of Alzheimer's, Parkinson's, and other neurological disorders.

27 Jan 2026

Tiny plastic particles may interfere with brain processes implicated in Parkinson’s disease

Micro- and nanoplastics are increasingly detected in human tissues, including the brain, and experimental evidence suggests they can interact with biological pathways central to Parkinson’s disease pathology. This review synthesises mechanistic data indicating that plastic particles may influence protein aggregation, neuroinflammation, mitochondrial dysfunction, and the gut–brain axis, while emphasising the need for prospective human studies.

26 Jan 2026

AI-designed NLRP3 inhibitor receives FDA clearance for Parkinson disease trials

Insilico Medicine (3696.HK), a clinical-stage drug discovery and development company driven by generative artificial intelligence (AI), today announced that ISM8969, an orally available NLRP3 inhibitor targeting inflammation and neurodegenerative disorders, has recently received investigational new drug (IND) clearance from the U.S. Food and Drug Administration (FDA), intended for the treatment of Parkinson's Disease.

23 Jan 2026

Unfolding the role of Hsp70 chaperones in neurodegeneration

Neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and amyotrophic lateral sclerosis (ALS) affect millions of people worldwide, yet treatments remain largely limited to symptom management.

22 Jan 2026

Rhythmic carbon dioxide exposure may enhance brain waste clearance mechanisms

Abnormal clumps of proteins like α-synuclein, amyloid beta and tau are associated with neurodegenerative conditions like Parkinson's and Alzheimer's disease, but a waste removal mechanism called the glymphatic pathway can clear these proteins and other metabolic byproducts from the brain.

20 Jan 2026

Researchers discover a biochemical route that plays role in Parkinson's disease

About 1 million Americans suffer from Parkinson's disease, with around 90,000 new cases diagnosed each year, according to the Parkinson's Foundation.

20 Jan 2026

Fruit fly study identifies genes regulating dopamine and sleep

Dopamine in the brain influences movement, learning, motivation and sleep. In humans, problems with dopamine are linked to conditions like Parkinson's disease, depression and sleep disorders.

13 Jan 2026

Study uncovers a neural brake that limits motivation during unpleasant situations

Most of us know the feeling: maybe it is making a difficult phone call, starting a report you fear will be criticized, or preparing a presentation that's stressful just to think about.

9 Jan 2026

Parkinson’s disease may stem from iron starvation rather than iron overload

This perspective argues that Parkinson’s disease may involve functional iron deficiency, where bioavailable iron is limited despite normal or elevated total iron in the brain. The authors propose that iron sequestration, not iron toxicity alone, may impair dopamine synthesis and neuronal survival.

6 Jan 2026

AI model can predict a person's disease risk using sleep data

A poor night's sleep portends a bleary-eyed next day, but it could also hint at diseases that will strike years down the road.

6 Jan 2026

Finger-prick blood tests enable remote detection of Alzheimer’s biomarkers

A groundbreaking international study has demonstrated that Alzheimer's disease biomarkers can be accurately detected using simple finger-prick blood samples that can be collected at home and mailed to laboratories without refrigeration or prior processing.

5 Jan 2026