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Lactate is essential to buffering the effects of a carbohydrate meal, study shows

As a student competing in track and field at his Parlier high school, Robert Leija was obsessed with how to improve his performance and, in particular, prevent the buildup of lactic acid in his muscles during training.

15 May 2024

Genetic link identified between inflammatory bowel disease and Parkinson's disease

The researchers found, as expected from prior studies that LRRK2 is associated with IBD-PD and discovered new associations as well.

15 May 2024

Enhanc3D Genomics appoints Hazel Jones as Chief Executive Officer

Enhanc3D Genomics, a company developing disruptive technologies to unlock the 3D genome for use in novel target identification and unique patient stratification, today announced the appointment of Hazel Jones as Chief Executive Officer, after a successful six-month tenure as interim CEO and COO.

From Enhanc3D Genomics 15 May 2024

Optibrium partners with FMC Corporation to transform agrochemical discovery

Optibrium, a leading developer of software and AI solutions for drug discovery, has signed a license agreement for its AI-powered discovery platform, Cerella™, with FMC Corporation (FMC), a global leader in crop protection.

From Optibrium Ltd. 15 May 2024

New study identifies 17 genes driving clonal hematopoiesis in aging blood cells

Scientists have discovered 17 additional genes that drive the abnormal overgrowth of mutated blood cells as we age. The findings, published today (14 May) in Nature Genetics, provide a more complete view of the genetic factors behind clonal hematopoiesis – a process associated with ageing and linked to increased risks of blood cancers.

15 May 2024

Metabolomics study finds biomarkers predicting autism in newborns

A study in Communications Biology utilized metabolomics in newborns to identify markers that might predict autism spectrum disorder (ASD), finding distinct metabolic profiles in children with ASD compared to typically developing children.

14 May 2024

Sleep and anesthesia hinder brain toxin clearance, study reveals

Researchers found that brain clearance is reduced during both sleep and anesthesia, contradicting the belief that these states enhance toxin removal.

14 May 2024

St. Jude researchers unveil mechanisms to block PXR and enhance drug potency

Deaths from cancer or infections can occur when available treatments are ineffective. Once turned on, pregnane X receptor (PXR) activates the expression of genes encoding enzymes that metabolize external chemicals, including drugs.

14 May 2024

Innovative 'mini-brains' could revolutionize Alzheimer's diagnosis and treatment

Using an innovative new method, a University of Saskatchewan (USask) researcher is building tiny pseudo-organs from stem cells to help diagnose and treat Alzheimer's.

14 May 2024

New mechanism discovered to weaken pseudomonas aeruginosa virulence

The opportunistic bacterial pathogen Pseudomonas aeruginosa is dangerous due to its resistance to multiple antibiotics.

14 May 2024

Research unveils the dual subdomain structure of the centromere

Researchers from the Kops group in collaboration with researchers from the University of Edinburgh, made a surprising new discovery in the structure of the centromere, a structure that is involved in ensuring that chromosomes are segregated properly when a cell divides.

14 May 2024

Scientists unlock mystery behind a deadly strain of cholera bacteria

A deadly strain of cholera bacteria that emerged in Indonesia back in 1961 continues to spread widely to this day, claiming thousands of lives around the world every year, sickening millions -; and, with its persistence, baffling scientists.

14 May 2024

Unraveling the genetic connection between IBD and Parkinson's disease

Researchers at the Icahn School of Medicine at Mount Sinai have made a significant discovery, identifying genetic connections between inflammatory bowel disease (IBD) and Parkinson's disease (PD).

14 May 2024

Study sheds light on the crucial role of glutamate tRNA fragments in brain aging and Alzheimer's disease

A significant research paper published in the journal Cell Metabolism by the team of Prof. LIU Qiang at the University of Science and Technology of China reveals the critical role of glutamate tRNA fragments in brain aging and Alzheimer's disease.

14 May 2024

Experimental gene therapy shows promise for treating herpes infections

Researchers at Fred Hutch Cancer Center have found in pre-clinical studies that an experimental gene therapy for genital and oral herpes removed 90% or more of the infection and suppressed how much virus can be released from an infected individual, which suggests that the therapy would also reduce the spread of the virus.

13 May 2024

Genetic analysis suggests the sudden emergence of threatening viruses

Suddenly they appear and - like the SARS-CoV-2 coronavirus - can trigger major epidemics: Viruses that nobody had on their radar.

13 May 2024

Research explores the effects of nuclear magnetic resonance on internal clock of cells

A research collaboration between the Faculty of Biochemistry and Molecular Medicine at the University of Oulu, Finland, the University of Innsbruck, Austria, and Florida Tech, USA, explored the effects of nuclear magnetic resonance on the internal clock of cells at different times of day and under oxygen deprivation.

13 May 2024

Protein mechanics key to cell nucleus entry, study finds

Researchers at the Francis Crick Institute and King's College London have discovered that how soft or rigid proteins are in certain regions can dictate how fast or slow they enter the nucleus.

13 May 2024

Research unlocks the role of macrophages in cancer relapse

Researchers from the Cancer Science Institute of Singapore at the National University of Singapore (NUS), have achieved breakthroughs in understanding relapse after chemotherapy for a type of cancer known as diffuse large B-cell lymphoma (DLBCL).

13 May 2024

ArgusEye closes €2.8 million funding to accelerate bioprocessing

ArgusEye, a provider of innovative sensor solutions for real-time monitoring of biological systems, today announced the close of its funding, raising €2.8 million EUR (~£2.4 million GBP) bringing the total raised by the Company to €3.45 million EUR (~£3 million GPB).

From ArgusEye AB 13 May 2024