Gastrointestinal Tract News and Research

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Newly discovered adhesion GPCR mayo controls midgut development in Drosophila

Adhesion GPCRs belong to the large family of G protein-coupled receptors (GPCRs). There are about 700 variants in humans, which are responsible for sensory impressions, hormonal cycles, controlling the cardiovascular system and more.

15 Mar 2024

Ultra-processed foods: The new silent killer

From fizzy drinks to cereals and packaged snacks to processed meat, ultra-processed foods are packed with additives.

14 Mar 2024

New sprayable gel promises safer endoscopic surgeries

More than 20 million Americans undergo colonoscopy screenings every year, and in many of those cases, doctors end up removing polyps that are 2 cm or larger and require additional care.

12 Mar 2024

Boosting curcumin's absorption and effectiveness for disease prevention and therapy

The potential of nano-formulations to boost the bioavailability and bioactivity of curcumin.

12 Mar 2024

UH College of Pharmacy secures CPRIT funding to fight familial adenomatous polyposis

The University of Houston College of Pharmacy is included in a $68.5 million funding package from the Cancer Prevention and Research Institute of Texas (CPRIT).

11 Mar 2024

Innovative BioSUM device detects post-surgical leaks via pH changes

A new device tested in pigs enables monitoring and early detection of pH changes in deep tissues due to post-operative leaks following gastrointestinal surgery.

7 Mar 2024

Microbial signatures linked to immunotherapy response across cancers

The microbiome can identify those who benefit from combination immunotherapy across multiple different cancers, including rare gynecological cancers, biliary tract cancers and melanoma.

1 Mar 2024

Novel genetic mechanisms of tetracycline resistance in gut bacteria discovered

Antibiotic resistance is a significant and growing medical problem worldwide. Researchers at the Marine Biological Laboratory (MBL) and collaborators have found a novel genetic arrangement that may help a common bacterium in the human gut, Bacteroides fragilis, protect itself from tetracycline, a widely used antibiotic.

1 Mar 2024

Chronic underhydration linked to major health risks, study finds

Chronic underhydration has been linked to severe long-term health issues, including heart disease, diabetes, and kidney dysfunction, underscoring the need for increased hydration awareness and intervention strategies.

27 Feb 2024

Fenugreek seeds: A superfood for health and wellness, says new review

Research highlights the dietary significance and potential applications of fenugreek seeds, emphasizing their role in disease prevention, chronic condition management, and providing nutritional value, including their ability to reduce blood sugar and cholesterol levels.

27 Feb 2024

Gut bacteria may be responsible for sight loss in certain inherited eye diseases

Sight loss in certain inherited eye diseases may be caused by gut bacteria, and is potentially treatable by antimicrobials, finds a new study in mice co-led by a UCL and Moorfields researcher.

26 Feb 2024

Study links ultra-processed foods to gut health risks

A review in Nature Reviews Gastroenterology & Hepatology synthesizes evidence on the negative impacts of ultra-processed foods and food additives on gut health, linking them to chronic diseases and alterations in the gut microbiome.

25 Feb 2024

Researchers identify new therapeutic for patients with a rare autoimmune disease EGPA

An international team, including researchers from McMaster University and St. Joseph's Healthcare Hamilton, has identified a new therapeutic for patients with a rare autoimmune disease called eosinophilic granulomatosis with polyangiitis (EGPA).

24 Feb 2024

Unlocking sulfasalazine's mechanism of action in IBD-SpA patients

Although it is one of the oldest medications used to treat patients with inflammatory bowel disease (IBD) and an effective treatment for an associated arthritis condition called spondyloarthritis (SpA), sulfasalazine's mechanism of action has been unclear.

20 Feb 2024

Ultra-processed foods: A growing threat to public health

From fizzy drinks to cereals and packaged snacks to processed meat, ultra-processed foods are packed with additives.

20 Feb 2024

Tiny imaging device could advance gastrointestinal cancer detection

Gastrointestinal cancers (GCs) are among the most common forms of cancer and account for as much as one-third of all cancer deaths worldwide.

6 Feb 2024

Exercise shapes our gut health, study finds

Accelerometer-based study reveals physical activity levels significantly influence gut microbiota composition, linking moderate and vigorous exercise to beneficial microbial diversity and function.

3 Feb 2024

Comparing perioperative differences: Sleeve gastrectomy vs. Roux-en-Y gastric bypass

Study compares laparoscopic sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) in obese patients, finding both procedures have low, comparable perioperative risks and complications, challenging the criteria for selecting between the two surgeries.

1 Feb 2024