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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Salk researchers unveil SWI/SNF variants' role in macrophage immune responses

Bacteria, parasites, viruses-;the immune system tackles them all. At the front line of the human immune response are cells called macrophages, which are responsible for correctly identifying intruders and then directing how the entire immune system responds.

5 Jun 2024

Emerging strains of resistant ringworm pose new public health threats in the U.S.

Healthcare providers should watch out for new and highly contagious forms of ringworm or jock itch, which are emerging as a potential public health threat, according to a pair of reports.

5 Jun 2024

Study uncovers genetic clues to the cause of restless leg syndrome

Scientists have discovered genetic clues to the cause of restless leg syndrome, a condition common among older adults.

5 Jun 2024

Fertility warning: SARS-CoV-2 can linger in sperm for months after infection

Researchers at the University of São Paulo (USP) in Brazil have shown for the first time that SARS-CoV-2, the virus that causes COVID-19, can remain in the sperm of patients for up to 90 days after hospital discharge and up to 110 days after the initial infection, reducing semen quality.

4 Jun 2024

Study reveals new insight into how human telomeres function at the molecular level

The length of telomeres that protect the ends of our chromosomes should be tightly regulated. Those that are too long predispose to cancer, and those that are too short lose their protective ability, resulting in telomere disorders with serious health consequences.

4 Jun 2024

Wistar scientists develop Persistent Multivalent T Cell Engager for advanced kidney cancer

Advanced clear cell renal cell carcinoma (ccRCC) is a deadly form of kidney cancer with few treatment options; even with new immunotherapies, only around one in 10 patients ultimately survive.

4 Jun 2024

Study sheds light on the disease development of Facioscapulohumeral Muscular Dystrophy

A recent study has found that the SMCHD1 protein plays a key role in controlling how genes are processed, which affects the progression of Facioscapulohumeral Muscular Dystrophy (FSHD).

4 Jun 2024

Novel combination treatment outperforms standard therapy in patients with EGFR NSCLC

The combination of the antibody amivantamab and lazertinib, a drug targeting EGFR, shows better clinical benefits compared to standard treatment in patients with advanced or metastatic non-small cell lung cancer with EGFR gene mutations who also present one of these poor prognosti markers: brain and/or liver metastases, p53 gene co-mutations, or the presence of circulating tumor DNA.

4 Jun 2024

Proteomic profiling reveals sexual dimorphism and immune system alterations in Werner syndrome

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 10, entitled, "Integrated liver and serum proteomics uncover sexual dimorphism and alteration of several immune response proteins in an aging Werner syndrome mouse model."

4 Jun 2024

New computational method developed for linking DNA marks to gene activity

Scientists at La Jolla Institute for Immunology (LJI) have developed a new computational method for linking molecular marks on our DNA to gene activity.

4 Jun 2024

Family's rare telomere mutation reveals new insights into telomere flexibility and disease

Researchers discovered a rare telomere mutation (TTAGGT) in a family, revealing that human telomeres can tolerate non-canonical sequences, impacting telomere maintenance and disease.

4 Jun 2024

Foam technology revolutionizes gene therapy, boosting efficiency and safety

Liquid foam gene delivery significantly enhances transfection efficiency and safety, offering a cost-effective alternative to conventional methods.

3 Jun 2024

Intermittent fasting with protein pacing trumps calorie restriction in gut health and weight loss

A recent study in Nature Communications found that intermittent fasting with protein pacing (IF-P) is more effective than continuous calorie restriction (CR) in improving gut microbiota and metabolomic profiles, leading to greater weight and fat loss.

2 Jun 2024

Polygenic risk score shows potential to predict survival outcomes in breast cancer patients

Data from a large prospective cohort study reveal that a polygenic risk score has the potential to predict survival outcomes in patients with breast cancer.

31 May 2024

Non-coding gene mutation linked to monogenic neurodevelopmental disorders

Researchers at the Icahn School of Medicine at Mount Sinai and others have identified a neurodevelopmental disorder, caused by mutations in a single gene, that affects tens of thousands of people worldwide.

31 May 2024

Life's Essential 8: key to reducing heart disease and mortality through epigenetics

Whether DNA methylation-based epigenetic age biomarkers mediate the associations between LE8 score and risks of CVD, CVD-specific mortality, and all-cause mortality.

31 May 2024

Researchers uncover two classes of genetic causes for pediatric chordoma

Little is known about the genetics and biology of chordoma, a rare and aggressive bone tumor. Chordomas occur in approximately one in a million people in the U.S. a year and only five percent of these are in children.

30 May 2024

Thailand grapples with colorectal cancer epidemic

According to research led by Prof. Varut Lohsiriwat, Professor of Surgery, Division of General Surgery (Section of Colorectal Surgery) of Siriraj Hospital, at Mahidol University, CRC is the third most common cancer in Thailand, accounting for 11% of the cancer burden. It is the only malignancy with an increased incidence in both genders in the country.

30 May 2024

Study reveals key to closing Black-White COVID-19 vaccination gap

Early in the Covid-19 pandemic, Black Americans were more hesitant to take the Covid-19 vaccine than were White Americans. As the pandemic went on, however, the disparity in vaccination rates between Black and White adults declined.

30 May 2024

Miniaturized CRISPR protein opens door for gene therapy with adeno-associated virus

Researchers have developed a novel version of a key CRISPR gene-editing protein that shows efficient editing activity and is small enough to be packaged within a non-pathogenic virus that can deliver it to target cells.

30 May 2024

DNA News and Research

Further Reading

Salk researchers unveil SWI/SNF variants' role in macrophage immune responses

Emerging strains of resistant ringworm pose new public health threats in the U.S.

Study uncovers genetic clues to the cause of restless leg syndrome

Fertility warning: SARS-CoV-2 can linger in sperm for months after infection

Study reveals new insight into how human telomeres function at the molecular level

Wistar scientists develop Persistent Multivalent T Cell Engager for advanced kidney cancer

Study sheds light on the disease development of Facioscapulohumeral Muscular Dystrophy

Novel combination treatment outperforms standard therapy in patients with EGFR NSCLC

Proteomic profiling reveals sexual dimorphism and immune system alterations in Werner syndrome

New computational method developed for linking DNA marks to gene activity

Family's rare telomere mutation reveals new insights into telomere flexibility and disease

Foam technology revolutionizes gene therapy, boosting efficiency and safety

Intermittent fasting with protein pacing trumps calorie restriction in gut health and weight loss

Polygenic risk score shows potential to predict survival outcomes in breast cancer patients

Non-coding gene mutation linked to monogenic neurodevelopmental disorders

Life's Essential 8: key to reducing heart disease and mortality through epigenetics

Researchers uncover two classes of genetic causes for pediatric chordoma

Thailand grapples with colorectal cancer epidemic

Study reveals key to closing Black-White COVID-19 vaccination gap

Miniaturized CRISPR protein opens door for gene therapy with adeno-associated virus

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