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Researchers examine the immune response of a hypervaccinated individual

Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum Erlangen have examined a man who has received more than 200 vaccinations against Covid-19. They learned of his case via newspaper reports.

5 Mar 2024

Nomogram could be a game-changer for predicting alcohol-related liver cancer risk

Liver cancer, unfortunately, is the sixth most common cancer and the third most frequent cause of cancer-related death globally.

5 Mar 2024

Identifying antiviral protein IFN-γ as a potential biomarker for Long COVID

SARS-CoV-2 triggers the production of the antiviral protein IFN-γ, which is associated with fatigue, muscle ache and depression. New research shows that in Long COVID patients, IFN-y production persists until symptoms improve, highlighting a potential biomarker and a target for therapies.

24 Feb 2024

Machine learning model to determine associations between metabolic syndrome and lactation

Machine learning models to investigate the relationship of lactation with metabolic syndrome risk.

22 Feb 2024

Study highlights an immunological mechanism underlying Long COVID

SARS-CoV-2 triggers the production of the antiviral protein IFN-γ, which is associated with fatigue, muscle ache and depression.

21 Feb 2024

Virginia Tech receives grant for improving rural wastewater pathogen detection

Testing wastewater to assess the spread of the COVID-19 virus became common and well-publicized during the pandemic, but it has been focused mostly on urban areas.

16 Feb 2024

Risk of non-alcoholic fatty liver disease for cardiovascular disease and all cause death in patients with type 2 diabetes mellitus

Researchers investigated the link between non-alcoholic fatty liver disease in individuals with type 2 diabetes mellitus (T2DM) and all-cause death and cardiovascular disease.

16 Feb 2024

Chula researchers develop wireless hepatitis B test kit for rapid diagnosis

Chula researchers have developed a remarkable wireless hepatitis B virus test kit to screen for infection and collect data for an online database that's fast and complete in one step. Industrial production is targeted for use throughout the country.

15 Feb 2024

Identifying immunotherapy resistance in liver cancer linked to steatotic disease

A research team of Canadian and French scientists, led by INRS professor Maya Saleh, has been investigating immunotherapy resistance in certain patients with hepatocellular carcinoma (HCC) associated with steatotic liver disease.

14 Feb 2024

Drug repurposing study finds lonafarnib effective against RSV

A study in Nature Communications identifies lonafarnib from the ReFRAME drug-repurposing library as a potent inhibitor of the RSV fusion protein, showing promise in reducing RSV infection in vitro and in vivo.

11 Feb 2024

COVID-19 may increase risk of pregnancy complications through placental DNA changes

DNA changes consistent with life-threatening pregnancy complications have been found in the placentas of pregnant women infected by COVID-19, according to University of Queensland researchers.

8 Feb 2024

Paxlovid enhances treatment options for COVID-19 patients

The design, synthesis, and mechanism of action of Paxlovid.

6 Feb 2024

New points-to-consider in the diagnosis, treatment of systemic hyperinflammatory syndromes

Hemophagocytic lymphohistiocytosis (HLH) and macrophage activation syndrome (MAS) are life-threatening systemic hyperinflammatory syndromes.

5 Feb 2024

Phase II clinical trial evaluates the safety and efficacy of a Muse cell-based product in patients with ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive loss of motor functions, which eventually leads to death within 5 years of its onset.

1 Feb 2024

Study: Up to 10% of dementia cases in veterans may be caused by liver disease

As many as 10% of older U.S. veterans diagnosed with dementia may suffer instead from reversible cognitive decline caused by advanced liver disease, according to an analysis from the Virginia Commonwealth University's School of Medicine and the Richmond VA Medical Center.

31 Jan 2024

Researchers detect genetic traces of hepatitis E viruses in wastewater

Researchers have identified genetic traces of hepatitis E viruses in almost 73 percent of wastewater samples from North-Rhine Westphalia.

31 Jan 2024

New DNA-based vaccine can induce strong antibody response against SARS-CoV-2

Using a virus-like delivery particle made from DNA, researchers from MIT and the Ragon Institute of MGH, MIT, and Harvard have created a vaccine that can induce a strong antibody response against SARS-CoV-2.

30 Jan 2024

3D-printed liver model paves way for new MASH treatments

Metabolic dysfunction- associated steatohepatitis, or MASH, is an inflammatory, liver-scarring disease that has reached epidemic proportions, with an estimated 1.5% to 6.5% of U.S. adults afflicted by the condition, and roughly 24% of adults having nonalcoholic fatty liver disease (NAFLD).

23 Jan 2024

Study provides valuable insights into the evolutionary dynamics of hepatitis E virus

A combination therapy with multiple drugs is more effective than just one active compound. To begin with, at least.