Positron Emission Tomography News and Research

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UK's first-of-its-kind total-body PET imaging platform could enhance quality and speed of drug discovery

A partnership between Medicines Discovery Catapult (MDC), the Medical Research Council (MRC) and Innovate UK will deliver scientific breakthroughs with the launch of the UK's first-of-its-kind national total-body positron emission tomography (PET) imaging platform for drug discovery

9 Oct 2023

$10.2M NIH grant awarded to study risk factors for malignant arrhythmias in mitral valve prolapse

Researchers at the Icahn School of Medicine at Mount Sinai have been awarded a $10.2 million grant from the National Heart, Lung and Blood Institute of the National Institutes of Health to investigate risk factors for malignant arrhythmias in mitral valve prolapse.

26 Sep 2023

Scientists decode the marker protein that can be used to ‘‘see’’ neuroinflammation

Inflammation is the sign that our body is defending itself against an aggression. But when this response escalates, for example in the brain, it can lead to serious neurological or psychiatric diseases.

25 Sep 2023

Comparing two plasma p-tau217 assays for Alzheimer's detection and monitoring

Researchers compared two commercially available blood tests based on the biomarker p-tau217 for diagnosing Alzheimer's disease in 294 patients. Both tests demonstrated robust diagnostic capabilities, strongly correlating with established Alzheimer's biomarkers from PET scans.

24 Sep 2023

New genetic test reveals a person’s predisposition to happiness

Your happiness levels aren't only based on external events. Genome testing can reveal how happy and optimistic you are predisposed to be. A leading testing expert reveals how variations of a key gene, CNR1, may have a significant impact on your level of happiness.

15 Sep 2023

Controlling traditional cardiovascular risk factors can prevent Alzheimer's and other dementias

Cardiovascular disease and dementia frequently occur together in elderly people. Nevertheless, few longitudinal studies have examined how atherosclerosis and its associated risk factors affect brain health from middle age.

30 Aug 2023

Engineered ACE2 decoy shows promise as COVID-19 treatment

Researchers from Japan demonstrated that an engineered angiotensin-converting enzyme 2 (ACE2) receptor, which showed the potential to remarkably reduce the emergence of resistant virus strains, could successfully exert its therapeutic effect in primates, which may open avenues for the application of the technology for the treatment of humans.

30 Aug 2023

A review of the neurological imaging techniques in dementia diagnosis

Researchers reviewed existing data on the contribution of neuroimaging modalities such as magnetic resonance imaging.

28 Aug 2023

The most recent neuroimaging procedures and machine learning approaches for the prediction of Alzheimer’s progression

Researchers examined recent studies exploring neuroimaging modalities aided by advanced machine learning (ML) algorithms.

24 Aug 2023

Is there an association between sleep-disordered breathing and Alzheimer's disease?

Researchers evaluated the impact of sleep-disordered breathing (SDB) on neuroimaging biomarkers of Alzheimer's disease (AD).

21 Aug 2023

Phase I trial shows promise: Brain stimulation spurs upper-extremity recovery in stroke patients

Researchers performed an open-label phase I trial.

18 Aug 2023

Study detects biomarker changes nearly 30 years before symptom onset of Alzheimer’s disease

A new paper has shown how Alzheimer’s disease pathology comes into being over a period of almost three decades.

10 Aug 2023

Tau PET shows promise for early diagnosis and treatment of Alzheimer's disease

Alzheimer's disease, one of the most common neurodegenerative diseases, leads to progressive loss of memory and autonomy.

9 Aug 2023

What are some recent advancements in proteomics-driven pancreatic oncology research?

The application of proteomics-driven biomarkers for early detection, diagnosis, and treatment of pancreatic cancer.

9 Aug 2023

Trial evaluates purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder

Researchers investigated the safety and pharmacokinetics of JNJ-54175446 in a double-blind, multicenter, randomized controlled trial (RCT).

31 Jul 2023

The role of vasomotor reactivity in COVID-19 patients

Researchers searched and collated the most relevant published literature on cerebral hemodynamic changes in COVID-19 patients.

27 Jul 2023

The link between constipation and cognitive decline

Researchers report the worsening of cognition among chronically constipated individuals.

25 Jul 2023

Donanemab: A trailblazer for Alzheimer's disease treatment?

A recent study evaluated the efficacy and side effects of donanemab, an antibody that could possibly clear brain amyloid plaque in early symptomatic Alzheimer disease (AD).

20 Jul 2023

Sense of smell may hold clues to Lewy body pathology: new evidence emerges

Researchers evaluated the impact of Lewy body (LB) positivity (+) on clinical outcomes such as cognition and smell among cognitively.