Gene Editing News and Research

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Intranasal delivery of CRISPR/Cas9 therapeutics may help treat chronic anxiety

A study in mice reports a CRISPR/Cas9 gene-editing delivery system, capable of bypassing the blood-brain-barrier and modulating neuronal receptor pathways, to treat chronic anxiety.

20 Jun 2023

Researchers identify several steps in a cellular process responsible for triggering inflammatory responses

Cedars-Sinai investigators have identified several steps in a cellular process responsible for triggering one of the body's important inflammatory responses.

16 Jun 2023

ATTR amyloidosis cardiomyopathy can be reversed, study reports

Three men who had heart failure caused by the build-up of sticky, toxic proteins are now free of symptoms after their condition spontaneously reversed in an unprecedented case described by a team at UCL (University College London) and the Royal Free Hospital.

7 Jun 2023

Novel gene-editing strategy harnesses an unusual protective ability to eliminate HIV-1 infection

Genetic alterations that give rise to a rare, fatal disorder known as MOGS-CDG paradoxically also protect cells against infection by viruses.

19 May 2023

New CRISPR genome-editing technology helps scientists to explore many cancer-linked mutations

Genomic studies of cancer patients have revealed thousands of mutations linked to tumor development.

11 May 2023

Study identifies key genetic mechanism of drug resistance in the deadliest malaria parasites

An important genetic mechanism of drug resistance in one of the deadliest human malaria parasites has been identified in a new study published in Nature Microbiology.

11 May 2023

New approach for efficient engineering of cell and gene therapies

A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods.

28 Apr 2023

How inert, sleeping bacteria spring back to life

Solving a riddle that has confounded biologists since bacterial spores -; inert, sleeping bacteria -; were first described more than 150 years ago, researchers at Harvard Medical School have discovered a new kind of cellular sensor that allows spores to detect the presence of nutrients in their environment and quickly spring back to life.

27 Apr 2023

Using the gene-editing tool to model certain liver tumor subtypes

Mutations in our genes can lead to severe problems, like colon or liver cancer. But cancer is very complex.

10 Apr 2023

New finding in roundworms upends classical thinking about animal cell differentiation

Researchers have spotted how specific proteins within the chromosomes of roundworms enable their offspring to produce specialized cells generations later, a startling finding that upends classical thinking that hereditary information for cell differentiation is mostly ingrained within DNA and other genetic factors.

7 Apr 2023

‘Glow-in-the-dark’ proteins could make disease diagnosis quicker and easier

Despite recent advancements, many highly sensitive diagnostic tests for viral diseases still require complicated techniques to prepare a sample or interpret a result, making them impractical for point-of-care settings or areas with few resources.

15 Mar 2023

New genetic animal model may inform potential therapeutic options for Down syndrome

National Institutes of Health researchers compared a new genetic animal model of Down syndrome to the standard model and found the updated version to be more similar to the changes seen in humans.

14 Mar 2023

Common scientific method to analyze DNA in early human embryos fails to accurately reflect gene edits

A commonly used scientific method to analyze a tiny amount of DNA in early human embryos fails to accurately reflect gene edits, according to new research led by scientists at Oregon Health & Science University.

7 Mar 2023

OHSU researchers confirm first-ever nonhuman primate model of Usher syndrome

Those with Usher Syndrome -- the leading hereditary cause for simultaneous deafness and blindness, for which there is no treatment -- may have a new reason for hope now that researchers have confirmed the first-ever nonhuman primate model of their disease.

13 Feb 2023

Gene Editing News and Research

Intranasal delivery of CRISPR/Cas9 therapeutics may help treat chronic anxiety

Researchers identify several steps in a cellular process responsible for triggering inflammatory responses

ATTR amyloidosis cardiomyopathy can be reversed, study reports

Novel gene-editing strategy harnesses an unusual protective ability to eliminate HIV-1 infection

New CRISPR genome-editing technology helps scientists to explore many cancer-linked mutations

Study identifies key genetic mechanism of drug resistance in the deadliest malaria parasites

New approach for efficient engineering of cell and gene therapies

How inert, sleeping bacteria spring back to life

Using the gene-editing tool to model certain liver tumor subtypes

New finding in roundworms upends classical thinking about animal cell differentiation

‘Glow-in-the-dark’ proteins could make disease diagnosis quicker and easier

New genetic animal model may inform potential therapeutic options for Down syndrome

Common scientific method to analyze DNA in early human embryos fails to accurately reflect gene edits

OHSU researchers confirm first-ever nonhuman primate model of Usher syndrome

Highly effective detection of cancer biomarkers using CRISPR

New discovery about microglia heralds myriad possibilities for treating neurodegenerative diseases

AI tool promises to accelerate the development of gene therapies on a large scale

Protein discovery could lead to more effective treatments for lymphoma and lung cancer

Structure and function of a newly discovered CRISPR immune system revealed

Mutations responsible for common inherited heart condition corrected using CRISPR-Cas9 therapy

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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