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Genetic insights unveil promising therapeutic targets for critical COVID-19

Genetic insights unveil promising therapeutic targets for critical COVID-19

Critical COVID-19 illness reveals genetic associations with immunomodulatory therapies, as identified in a comprehensive analysis of 24,202 cases. This study uncovers novel genome-wide significant associations, highlighting potential druggable targets for inflammatory signaling, immunometabolism, and viral replication, offering insights into therapeutic implications.

21 May 2023

Going nuts for heart health: Mixed nuts consumption shows promising effects on cardiovascular risk factors

Going nuts for heart health: Mixed nuts consumption shows promising effects on cardiovascular risk factors

Researchers investigated the effect of daily consumption of mixed nuts on cardiovascular disease biomarkers in overweight and obese adults.

18 May 2023

New study finds elevated inflammatory cytokines and lymphocytes linked to rare cases of myocarditis after COVID-19 vaccination

New study finds elevated inflammatory cytokines and lymphocytes linked to rare cases of myocarditis after COVID-19 vaccination

Researchers investigated a cohort of patients who developed myocarditis after SARS-CoV-2 mRNA vaccination.

10 May 2023

Boosting gut health with short-chain fatty acids

Boosting gut health with short-chain fatty acids

Research paper provides an overview of short-chain fatty acids (SCFAs) and their role in regulating gut homeostasis. It also discusses SCFA-producing bacteria and potential therapeutic approaches to boost SCFA levels in the gut to treat related diseases.

9 May 2023

Breast cancer tumors disrupt the development of an immune response to favor their own growth

Breast cancer tumors disrupt the development of an immune response to favor their own growth

Researchers at Baylor College of Medicine and collaborating institutions have identified a strategy cancerous tumors use to remotely disrupt the development of an immune response that could stop their growth.

5 May 2023

New approach addresses the challenge of directly connecting genetic variants to human traits, health

New approach addresses the challenge of directly connecting genetic variants to human traits, health

A major challenge in human genetics is understanding which parts of the genome drive specific traits or contribute to disease risk. This challenge is even greater for genetic variants found in the 98% of the genome that does not encode proteins.

5 May 2023

Unlocking the puzzle: How ACE2 shapes macrophage responses in COVID-19

Unlocking the puzzle: How ACE2 shapes macrophage responses in COVID-19

A new study investigates whether SARS-CoV-2 can enter and replicate in macrophages and whether ACE2 is involved in these mechanisms.

4 May 2023

Study identifies immune signature to predict severe COVID-19 in cardiovascular patients

Study identifies immune signature to predict severe COVID-19 in cardiovascular patients

Research investigates whether the severity of SARS-CoV-2 infection can be predicted by analyzing the immunophenotype in the blood of cardiovascular disease (CVD) patients.

1 May 2023

Researchers develop a backpack-based myeloid cell therapy for MS patients

Researchers develop a backpack-based myeloid cell therapy for MS patients

Multiple sclerosis (MS) is a devastating autoimmune disease that destroys the protective myelin covering around nerves, disrupting communication between the brain and body, and causing patients' ability to move and function to progressively decline.

21 Apr 2023

Is there a correlation between acute and chronic red wine intake and health?

Is there a correlation between acute and chronic red wine intake and health?

Researchers examined the correlations between acute and chronic red wine (RW) intake and health.

18 Apr 2023

How nanomedicine is revolutionizing care for cardiovascular disease

How nanomedicine is revolutionizing care for cardiovascular disease

Researchers review recent advancements in nanomedicine treatment options for cardiovascular disease.

6 Apr 2023

Study suggests psychosocial factors, not acute infections, contribute to long-COVID in young adults

Study suggests psychosocial factors, not acute infections, contribute to long-COVID in young adults

Researchers investigated the prevalence of post-coronavirus disease 2019 condition in adolescents and young adults

4 Apr 2023

Red blood cell hitch-hiking facilitates SARS-CoV-2 multi-organ spread

Red blood cell hitch-hiking facilitates SARS-CoV-2 multi-organ spread

Researchers assessed the infectious capacity of severe acute respiratory syndrome coronavirus 2 in plasma and red blood cells.

3 Apr 2023

Black sea urchin extract shows promise in combating atherosclerosis

Black sea urchin extract shows promise in combating atherosclerosis

A team of Italian scientists has identified potential anti-inflammatory and vasculoprotective effects of red cell extracts of the Black Sea urchin Arbacia lixula. The study has been published in the journal Nutrients.

30 Mar 2023

How do viral infections cause autoimmune diseases?

How do viral infections cause autoimmune diseases?

Researchers describe the pathological mechanisms of virus-induced autoimmune diseases.

28 Mar 2023

Myeloid cells can harbor HIV in people taking antiretroviral therapy

Myeloid cells can harbor HIV in people taking antiretroviral therapy

A subset of white blood cells, known as myeloid cells, can harbor HIV in people who have been virally suppressed for years on antiretroviral therapy, according to findings from a small study supported by the National Institutes of Health.

27 Mar 2023

Monocytes may be a stable reservoir of HIV in patients taking antiretroviral therapy

Monocytes may be a stable reservoir of HIV in patients taking antiretroviral therapy

To develop treatments that may one day entirely rid the body of HIV infection, scientists have long sought to identify all of the places that the virus can hide its genetic code.

27 Mar 2023

How does diet affect inflammation?

How does diet affect inflammation?

In a recent study published in the journal Nutrients, researchers in Italy suggest there is evidence that dietary factors may directly affect the immune system and play a role in chronic systemic inflammation.

26 Mar 2023

Curcumin reduces inflammatory responses in post-COVID vaccinated adults

Curcumin reduces inflammatory responses in post-COVID vaccinated adults

A new study published in the Nutrients Journal highlights the impact of curcumin supplementation on the immune response following the immunization of Coronavirus disease 2019 (COVID-19) survivors with a primary series of monovalent COVID-19 vaccines.

26 Mar 2023

A high-throughput CAMP assay for the evaluation of the vitamin D-dependent antimicrobial response

A high-throughput CAMP assay for the evaluation of the vitamin D-dependent antimicrobial response

A recent developed a novel and high-throughput assay to evaluate cathelicidin antimicrobial peptide.

16 Mar 2023

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