Amputation News and Research

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Groundbreaking therapy may provide a new treatment modality for biofilm infections in foot ulcers

A new £1.7m project to explore using plasma jets and antimicrobial dressings to treat debilitating - and potentially deadly - wound infections launches today.

1 Feb 2021

Multimodal pain regimen minimizes opioid exposure, relieves acute pain in trauma patients

A multimodal pain regimen (MMPR) designed to minimize opioid exposure and relieve acute pain associated with traumatic injury kept patient self-reported pain scores low while also reducing the daily and total amount of opioid drugs given to trauma patients.

21 Jan 2021

Mid-term clinical trial results of two cell therapies for critical limb ischemia show similar outcomes

Mid-term results of the first clinical trial designed specifically to evaluate the safety and effectiveness of two cell therapies that are showing early promise in treating angiitis-induced critical limb ischemia were released today in STEM CELLS Translational Medicine.

5 Jan 2021

FDA approves first implant system for adults who have above-the-knee amputations

The U.S. Food and Drug Administration today approved the Osseoanchored Prostheses for the Rehabilitation of Amputees (OPRA) Implant System, the first implant system marketed in the U.S. for adults who have transfemoral—or above-the-knee—amputations and who have or are anticipated to have rehabilitation problems with, or cannot use, a conventional socket prosthesis.

18 Dec 2020

Study: Paclitaxel-coated devices do not increase mortality for patients with peripheral artery disease

An interim analysis from the Swedish Drug-Elution Trial in Peripheral Arterial Disease (SWEDEPAD) has now been presented.

10 Dec 2020

Sensory stimulation improves perception of phantom limbs, leads to better muscle movement

A significant amount of research and development has gone into creating sophisticated prosthetic limbs and learning how to effectively control them.

8 Dec 2020

Thromboembolism in COVID-19 patients associated with higher risk of mortality

While respiratory issues continue to be the most common symptom of a COVID-19 infection, new research indicates the disease could also be associated with hypercoagulability, or increased tendency of the blood to clot.

23 Nov 2020

Experts highlight latest advancements in neurogenic classification and pain management

There have been significant advances in knowledge regarding the pathology, etiology, assessment, and treatment of several significant neurogenic pain disorders regularly encountered by neurorehabilitation professionals in both inpatient and outpatient care.

18 Nov 2020

Newer Type 2 diabetes medications could reduce kidney, heart disease risks

Two newer groups of medications prescribed primarily for Type 2 diabetes treatment (SGLT2 inhibitors and GLP-1 receptor agonists) could significantly reduce risks associated with chronic kidney disease (CKD) and heart disease.

28 Sep 2020

Enzyme insight could lead to new treatment approach for diabetic patients

Research led by the Centenary Institute has discovered that the lack of an enzyme in the liver called sphingosine kinase 2 results in pronounced insulin resistance and glucose intolerance, both symptoms of early stage type 2 diabetes.

15 Sep 2020

Combination of gout and diabetes carries increased risk of amputation

Diabetes mellitus and gout are ranked among the most common metabolic disorders in Western industrialised countries: According to figures published by the World Health Organization (WHO), around 60 million Europeans suffer from diabetes (2) and 18 million Europeans suffer from gout (3).

13 Aug 2020

Study shows lasting benefits of bone-anchored leg prostheses

After above-knee amputation, there is the option of a prosthesis that is placed directly in the thigh bone (osseointegration).

6 Aug 2020

Leading expert is sounding the alarm on newly-identified symptom of coronavirus

A VascularNurse Consultant and senior lecturer at the University of Huddersfield is sounding the alarm on a newly-identified symptom of the coronavirus, dubbed COVID-toes, after witnessing a sharp increase in the amount of patients being referred to vascular clinics, with similar symptoms to arterial disease but, who then test positive for COVID-19.

31 Jul 2020

Researchers show usefulness of potential 'phage cocktail' therapy on wound infections

Australian researchers have shown how viruses can be used to save lives, developing the potential use of bacteriophages in bandages to treat life-threatening golden staph infections which may not respond to traditional antibiotics.

30 Jul 2020

Study shows promise of a major breakthrough in healing chronic diabetic ulcers

A new study released today in STEM CELLS Translational Medicine shows promise of a major breakthrough in healing chronic foot ulcers resulting from diabetes.

28 Jul 2020

Medieval remedy can help treat modern day infections

Antibiotic resistance is an increasing battle for scientists to overcome, as more antimicrobials are urgently needed to treat biofilm-associated infections.

28 Jul 2020

Indiana University School of Medicine leads the first study of Diabetic Foot Consortium

Indiana University School of Medicine is leading the first study of the national Diabetic Foot Consortium sponsored by the National Institutes of Health (NIH) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

25 Jul 2020

First-ever multicenter network to study diabetic foot ulcers

Funded by the National Institutes of Health, six U.S. research institutions are launching the first-ever multicenter network to study diabetic foot ulcers, a common and burdensome complication of diabetes and the leading cause of lower limb amputations in the United States.

25 Jul 2020

Bacteriophages may play a key role in treating prosthetic joint infections

Bacteriophages, or phages, may play a significant role in treating complex bacterial infections in prosthetic joints, according to new Mayo Clinic research.

24 Jul 2020

Study may lead to new diagnostic and treatment strategies for fighting bone cancer

Osteosarcoma (OS) is the most common form of aggressive bone cancer. A MedUni Vienna study, led by geneticist Erwin Wagner, has uncovered new insights into the disease mechanisms of OS, paving the way for potential new diagnostic and treatment strategies for fighting the bone disease

21 Jul 2020