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Obesity linked to prostate cancer risk: New study uncovers inherited dangers from fathers

Obesity contributes to prostate cancer risk and can be inherited from obese fathers, as shown in a review of over 280 studies examining obesity's impact on carcinogenesis and heritability.

23 Nov 2023

Isolation measures during pandemic drove faster, more transmissible SARS-CoV-2 variants, study reveals

A Nature Communications study finds that isolation practices during the COVID-19 pandemic influenced the evolution of SARS-CoV-2, leading to variants with earlier, higher peak viral loads but shorter infection durations, suggesting a shift towards increased transmissibility.

23 Nov 2023

Research reveals how isolation measures influence SARS-CoV-2's evolutionary trajectory

Researchers used previously reported empirical clinical data analysis and multi-level mathematical modeling to forecast changes in SARS-CoV-2 dynamics during infection and evolution.

23 Nov 2023

Fecal microbiota transplantation boosts survival in metastatic colorectal cancer treatment

A recent study in eClinicalMedicine found that fecal microbiota transplantation, combined with fruquintinib and tislelizumab, significantly improved survival rates in patients with microsatellite stable metastatic colorectal cancer, showing manageable safety and notable increases in progression-free and overall survival.

15 Nov 2023

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Study reveals that senolytics can reduce aging in human brain organoids and mitigate COVID-19 neuropathology, suggesting their potential as a therapeutic strategy against brain aging and coronavirus-related neurological complications.

15 Nov 2023

Engineering approach reveals surprising macrophage phenotype with best tumor-targeting ability

Macrophages, a type of white blood cell that can destroy invading pathogens, have an innate ability to infiltrate tumor cells, making them a potentially important tool in treatments that use transplanted cells to fight disease, known as cell therapy.

15 Nov 2023

New diagnostic workflow improves detection of 5q-spinal muscular atrophy

5q-spinal muscular atrophy (5q-SMA) is one of the more common types of spinal muscular atrophy (SMA) affecting around one in ten thousand individuals worldwide.

15 Nov 2023

New lipidic peptide IK14004 shows promise in treating cancer and reducing autoimmune complications

A lipidic peptide, named IK14004.

15 Nov 2023

Intestinal MCT1 plays a crucial role in sex-dependent metabolic regulation

Monocarboxylate transporter 1 (MCT1) plays a crucial role in the transport of lactate, pyruvate, ketone bodies, and short-chain fatty acids (SCFA), as well as MCT1-targeted drugs in various tissues.

14 Nov 2023

Study reveals mechanisms underlying non-suppressible HIV viremia

Human immunodeficiency virus (HIV) works by entering specific immune cells and replicating inside them.

14 Nov 2023

AI-powered method could revolutionize cancer treatment by interpreting tumor tissue data

Researchers at Karolinska Institutet and SciLifeLab in Sweden have combined artificial intelligence (AI) techniques used in satellite imaging and community ecology to interpret large amounts of data from tumor tissue.

13 Nov 2023

Pioneering study finds predictive biomarker in lung adenocarcinoma

The potential of the transcriptome of tumor-adjacent normal lung tissue in predicting the prognosis of lung cancer.

13 Nov 2023

Research redefines rheumatoid arthritis: Over 314,000 cells analyzed for precise treatment strategies

A new paper recently published in Nature, reported the examination of synovial tissue from the joints of nearly 80 people with RA, in combination with RNA sequencing and surface protein analyses.

10 Nov 2023

How glucose restriction makes lung cancer cells more aggressive

One of the hallmarks of cancer cell development is its dependence on sugar, especially glucose, to grow and divide.

7 Nov 2023

Study validates first-in-class AI-driven digital pathology colorectal cancer diagnostic tool

In a peer-reviewed study published today in Nature Communications, a team of scientists from French-American techbio Owkin and pathology labs in France present a blind validation of MSIntuit CRC, a first-in-class AI-driven digital pathology diagnostic developed by Owkin, as a pre-screening tool aimed at optimizing the precision of diagnosis and treatment of colorectal cancer.

7 Nov 2023

Study links gut bacteria single-nucleotide polymorphisms to BMI

Researchers investigated the potential implications of single-nucleotide variations in gut-residing bacterial species (microbiome) on human health.

7 Nov 2023

Yabing Chen receives NIH grants to advance vascular disease research

Yabing Chen, Ph.D., has been awarded two National Institutes of Health grants totaling more than $5 million to further her research into vascular diseases ranging from hardening of the arteries to dementia.

6 Nov 2023

Is sleep apnea the missing link between high blood pressure and Alzheimer's?

Researchers explore the links between non-dipper hypertension, obstructive sleep apnea (OSA), and Alzheimer's disease (AD). They find that OSA may cause non-dipper hypertension, a condition that exacerbates AD symptoms, but also note that treating OSA can mitigate hypertension and potentially slow AD progression.

29 Oct 2023

UTHSC researcher part of team studying obesity-cancer connection

A University of Tennessee Health Science Center (UTHSC) researcher is a member of a prestigious team that has just received a highly competitive Endeavor Award totaling $3 million from The Mark Foundation for Cancer Research.

26 Oct 2023

New software tool provides a way for safer design of genome editing

A team of researchers has developed a software tool called DANGER (Deleterious and ANticipatable Guides Evaluated by RNA-sequencing) analysis that provides a way for the safer design of genome editing in all organisms with a transcriptome.

24 Oct 2023

Phenotype News and Research

Obesity linked to prostate cancer risk: New study uncovers inherited dangers from fathers

Isolation measures during pandemic drove faster, more transmissible SARS-CoV-2 variants, study reveals

Research reveals how isolation measures influence SARS-CoV-2's evolutionary trajectory

Fecal microbiota transplantation boosts survival in metastatic colorectal cancer treatment

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Engineering approach reveals surprising macrophage phenotype with best tumor-targeting ability

New diagnostic workflow improves detection of 5q-spinal muscular atrophy

New lipidic peptide IK14004 shows promise in treating cancer and reducing autoimmune complications

Intestinal MCT1 plays a crucial role in sex-dependent metabolic regulation

Study reveals mechanisms underlying non-suppressible HIV viremia

AI-powered method could revolutionize cancer treatment by interpreting tumor tissue data

Pioneering study finds predictive biomarker in lung adenocarcinoma

Research redefines rheumatoid arthritis: Over 314,000 cells analyzed for precise treatment strategies

How glucose restriction makes lung cancer cells more aggressive

Study validates first-in-class AI-driven digital pathology colorectal cancer diagnostic tool

Study links gut bacteria single-nucleotide polymorphisms to BMI

Yabing Chen receives NIH grants to advance vascular disease research

Is sleep apnea the missing link between high blood pressure and Alzheimer's?

UTHSC researcher part of team studying obesity-cancer connection

New software tool provides a way for safer design of genome editing

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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