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Bile acids: Balancing digestive health and liver toxicity

Bile acids are essential molecules the liver produces that play a critical role in digestion. They help us absorb fat-soluble vitamins and cholesterol from our food.

6 Jun 2024

Columbia scientists uncover true identity of gut's hardworking stem cells

Two independent studies by Columbia scientists suggest that research into the gut's stem cells over the past 15 years has been marred by a case of mistaken identity: Scientists have been studying the wrong cell.

6 Jun 2024

Injectable fish oil emulsion reduces brain damage in newborn rodents

An injectable emulsion containing two omega-3 fatty acids found in fish oil markedly reduced brain damage in newborn rodents after a disruption in the flow of oxygen to the brain near birth, a study by researchers at Columbia University Vagelos College of Physicians and Surgeons has found.

6 Jun 2024

Sedentary childhood linked to premature liver damage, study finds

An increase in sedentary time from childhood caused premature liver damage, a new study shows. However, light physical activity could reverse the risk.

6 Jun 2024

Proteomic fitness scores revolutionize disease prediction and personalized exercise plans

Research establishes a proteomic CRF score, linking it to improved prediction of mortality and multisystem disease risks, showing dynamic response to exercise training.

5 Jun 2024

Elevated TMAO levels linked to higher diabetes risk, study finds

A recent Nutrients study links elevated trimethylamine N-oxide (TMAO) levels with an increased risk of type 2 diabetes, highlighting the role of diet in diabetes prevention.

4 Jun 2024

Moderate choline intake lowers heart disease risk

A recent study from BMC Public Health found that moderate dietary choline intake is associated with a reduced risk of atherosclerotic cardiovascular disease (ASCVD) among US adults.

4 Jun 2024

5-Cog paradigm: A breakthrough in dementia diagnosis and care

The underdiagnosis of dementia, especially among Black and Hispanic patients, is a long-standing challenge in medicine.

4 Jun 2024

Novel combination treatment outperforms standard therapy in patients with EGFR NSCLC

The combination of the antibody amivantamab and lazertinib, a drug targeting EGFR, shows better clinical benefits compared to standard treatment in patients with advanced or metastatic non-small cell lung cancer with EGFR gene mutations who also present one of these poor prognosti markers: brain and/or liver metastases, p53 gene co-mutations, or the presence of circulating tumor DNA.

4 Jun 2024

Researchers discover age-related changes in the lipid metabolism of mice

Researchers at the RIKEN Center for Integrative Medical Sciences (IMS) have discovered numerous age-related changes in the lipid metabolism of mice, across both organs and sexes.

4 Jun 2024

Proteomic profiling reveals sexual dimorphism and immune system alterations in Werner syndrome

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 10, entitled, "Integrated liver and serum proteomics uncover sexual dimorphism and alteration of several immune response proteins in an aging Werner syndrome mouse model."

4 Jun 2024

New computational method developed for linking DNA marks to gene activity

Scientists at La Jolla Institute for Immunology (LJI) have developed a new computational method for linking molecular marks on our DNA to gene activity.

4 Jun 2024

Does eating chili pepper decrease or increase obesity risk?

Researchers in Frontiers in Nutrition investigate whether eating chili pepper decreases or increases the risk of obesity in U.S. adults.

3 Jun 2024

Vasomotor symptoms in menopausal women linked to greater risk for non-alcoholic fatty liver disease

Women experiencing moderate-to-severe vasomotor symptoms face a three times greater risk for metabolic-dysfunction-associated steatotic liver disease (MASLD) compared to those with mild symptom severity, according to research being presented Monday at ENDO 2024, the Endocrine Society's annual meeting in Boston, Mass.

3 Jun 2024

Long-term study reveals safety of metformin use during pregnancy

Metformin is safe to use during pregnancy to manage diabetes, with no long-term adverse effects on the children born and their mothers for at least 11 years after childbirth, according to research presented Sunday at ENDO 2024, the Endocrine Society's annual meeting in Boston, Mass.

3 Jun 2024

Two diabetes medications more beneficial in preventing major cardiovascular events

GLP-1 receptor agonists (GLP-1s) and SGLT-2 inhibitors lower the risk of major cardiovascular events like heart attacks and severe liver complications compared to other diabetes treatments, according to data being presented Sunday at ENDO 2024, the Endocrine Society's annual meeting in Boston, Mass.

3 Jun 2024

Childhood inactivity linked to increased risk of liver disease by young adulthood

Children who are sedentary for more than six waking hours a day have a significantly increased risk of severe fatty liver disease and liver cirrhosis by young adulthood, a new study finds.

3 Jun 2024

DefiniGEN and Atelerix collaborate to ship in vitro cell models internationally without the need for freezing or cryopreservation

DefiniGEN Ltd., and Atelerix Ltd., today announced they have successfully shipped in vitro liver models from the UK to a top tier pharma customer in the US. The agreement between the companies combines DefiniGEN’s mechanistically relevant iPSC hepatocytes (Opti-Heps) with Atelerix's hydrogel preservation technology, which prevents loss of function and enables even sensitive samples to remain stable at ambient temperatures for up to two weeks.

From Defini Gen 3 Jun 2024

Garlic proves potent in reducing blood sugar and cholesterol, study reveals

Study confirms garlic's significant benefits in lowering blood glucose and lipid levels, offering a natural remedy for metabolic disorders.

2 Jun 2024

Type 2 diabetes linked to higher cancer risk, especially with diabetic retinopathy, study finds

A recent study in BMC Medicine found that type 2 diabetes significantly increases the risk of various cancers, with the risk being even higher in patients with diabetic retinopathy (DR).

2 Jun 2024

Liver News and Research

Bile acids: Balancing digestive health and liver toxicity

Columbia scientists uncover true identity of gut's hardworking stem cells

Injectable fish oil emulsion reduces brain damage in newborn rodents

Sedentary childhood linked to premature liver damage, study finds

Proteomic fitness scores revolutionize disease prediction and personalized exercise plans

Elevated TMAO levels linked to higher diabetes risk, study finds

Moderate choline intake lowers heart disease risk

5-Cog paradigm: A breakthrough in dementia diagnosis and care

Novel combination treatment outperforms standard therapy in patients with EGFR NSCLC

Researchers discover age-related changes in the lipid metabolism of mice

Proteomic profiling reveals sexual dimorphism and immune system alterations in Werner syndrome

New computational method developed for linking DNA marks to gene activity

Does eating chili pepper decrease or increase obesity risk?

Vasomotor symptoms in menopausal women linked to greater risk for non-alcoholic fatty liver disease

Long-term study reveals safety of metformin use during pregnancy

Two diabetes medications more beneficial in preventing major cardiovascular events

Childhood inactivity linked to increased risk of liver disease by young adulthood

DefiniGEN and Atelerix collaborate to ship in vitro cell models internationally without the need for freezing or cryopreservation

Garlic proves potent in reducing blood sugar and cholesterol, study reveals

Type 2 diabetes linked to higher cancer risk, especially with diabetic retinopathy, study finds

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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