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Curcumin nanoparticles show promise in treating neurodegenerative diseases

Review demonstrates curcumin's neuroprotective effects in neurodegenerative diseases, enhancing its potential through innovative nanoparticle formulations. This advancement could significantly improve treatments for diseases like Parkinson's, Alzheimer's, and Multiple Sclerosis.

6 Jun 2024

Targeting synaptic lipid signaling: A novel approach to mental health treatment

Increased levels of bioactive lipids produced naturally in the body, which affect excitatory transmission between brain cells, promote mental disorders.

6 Jun 2024

JUN protein could slow prostate cancer growth, study finds

As prostate cancer progresses, it becomes increasingly aggressive and can metastasise. In this form, the tumor is difficult to treat, which is reflected in high mortality rates: Worldwide, the malignant disease of the prostate is the second most common cause of cancer death in men.

5 Jun 2024

Proteomic profiling reveals sexual dimorphism and immune system alterations in Werner syndrome

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 10, entitled, "Integrated liver and serum proteomics uncover sexual dimorphism and alteration of several immune response proteins in an aging Werner syndrome mouse model."

4 Jun 2024

Mouse study identifies sex differences at the cellular level for heart failure

Researchers investigated the impact of aldosterone infection in db/db mice on HFpEF, focusing on sex differences and alterations in intracellular calcium handling and cardiomyocyte electrophysiology.

4 Jun 2024

Omega-3 supplements show promise in battling osteoarthritis

A recent study in Nutrients reviewed the efficacy of omega-3 polyunsaturated fatty acids (PUFAs) in slowing the progression of osteoarthritis (OA) by reducing inflammation and supporting joint health.

2 Jun 2024

Single infusion of engineered T-cells achieves lasting asthma remission in mice

Researchers demostrate that durable asthma remission can be achieved with engineered and long-lived CAR T-cell treatment in mice.

31 May 2024

Study may facilitate the development of new personalized treatments for schizophrenia An International Study Publi...

An international study led by the Hospital del Mar Medical Research Institute, in collaboration with researchers from the Neuropsychopharmacology Group at the University of the Basque Country (UPV/EHU) and researchers from the CIBER of Mental Health (CIBERSAM), and published in Nature Communications, may facilitate the creation of new personalized treatments for people diagnosed with schizophrenia.

30 May 2024

Coupling bacteria-laden hydrogel and electronics for adaptive treatment of skin inflammation

Coupling skin bacteria-laden hydrogel and electronics, researchers have introduced the ABLE platform, a bioelectronics system that can deliver management and adaptive treatment of skin inflammation.

30 May 2024

Canagliflozin: A breakthrough in senolytic treatment for aging-related diseases

Aging-related physiological decline and the accumulation of senescent or aging cells in bodily tissues can trigger a number of diseases.

30 May 2024

Female and male heart failure may require distinct treatments

A new study from the UC Davis School of Medicine found striking differences at the cellular level between male and female mice with heart failure with preserved ejection fraction (HFpEF).

30 May 2024

New research highlights a promising approach to tackling for ALS

A recent collaborative research endeavor, published in the prestigious Cell Press journal Cell Reports Medicine, highlights a promising therapeutic avenue for amyotrophic lateral sclerosis (ALS).

29 May 2024

Study reveals new link between high temperature exposure and sphingolipid metabolism in obesity

In contemporary society, obesity has emerged as a worldwide chronic metabolic disorder, imposing substantial burdens on both individual health and healthcare systems.

29 May 2024

Study finds Plexin-B1 could be key to Alzheimer’s treatment, enhancing glial cell response

Researchers discovered that Plexin-B1 plays a crucial role in regulating peri-plaque glial nets in Alzheimer’s disease, potentially opening new avenues for treatment by targeting this protein.

29 May 2024

Phytochemicals show promise in treating neurological disorders by influencing the gut-brain axis

Researchers reviewed the potential therapeutic effects of phytochemicals on the gut-brain axis, finding they could influence brain function and reduce neurological symptoms by modulating gut microbiota.

26 May 2024

Non-hormonal sperm-specific approach offers a promising option for reversible male contraception

The world's population has increased by more than 2.6-fold in the last 60 years. The growing trend continues – projections indicate that the number of people living on our planet will grow to 9 billion by 2037 from 8 billion in 2022.

23 May 2024

Treating obesity using glucagon-like peptide-1-directed N-methyl-D-aspartate receptor inhibition

Bimodal drug that successfully cures obesity, hyperglycemia, and dyslipidemia in mouse models.

20 May 2024

Twendee X shows promise in reducing oxidative stress in systemic sclerosis

Autoimmune diseases occur when the body's immune system attacks healthy cells instead of protecting them.

17 May 2024

Johns Hopkins researchers identify key electrical activity behind congenital night blindness

In what they believe is a solution to a 30-year biological mystery, neuroscientists at Johns Hopkins Medicine say they have used genetically engineered mice to address how one mutation in the gene for the light-sensing protein rhodopsin results in congenital stationary night blindness.

17 May 2024

TRPS1 could serve as a new target for drugs against breast cancer

The mammary gland is a complex tissue comprising a variety of cell types. Their proper functioning is crucial for the health of the breast.

16 May 2024

Mouse Model News and Research

Curcumin nanoparticles show promise in treating neurodegenerative diseases

Targeting synaptic lipid signaling: A novel approach to mental health treatment

JUN protein could slow prostate cancer growth, study finds

Proteomic profiling reveals sexual dimorphism and immune system alterations in Werner syndrome

Mouse study identifies sex differences at the cellular level for heart failure

Omega-3 supplements show promise in battling osteoarthritis

Single infusion of engineered T-cells achieves lasting asthma remission in mice

Study may facilitate the development of new personalized treatments for schizophrenia An International Study Publi...

Coupling bacteria-laden hydrogel and electronics for adaptive treatment of skin inflammation

Canagliflozin: A breakthrough in senolytic treatment for aging-related diseases

Female and male heart failure may require distinct treatments

New research highlights a promising approach to tackling for ALS

Study reveals new link between high temperature exposure and sphingolipid metabolism in obesity

Study finds Plexin-B1 could be key to Alzheimer’s treatment, enhancing glial cell response

Phytochemicals show promise in treating neurological disorders by influencing the gut-brain axis

Non-hormonal sperm-specific approach offers a promising option for reversible male contraception

Treating obesity using glucagon-like peptide-1-directed N-methyl-D-aspartate receptor inhibition

Twendee X shows promise in reducing oxidative stress in systemic sclerosis

Johns Hopkins researchers identify key electrical activity behind congenital night blindness

TRPS1 could serve as a new target for drugs against breast cancer

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