Clinical Trial News and Research

RSS

AI-enabled ECG system significantly reduces hospital mortality rates by identifying at-risk patients

A study in Nature Medicine evaluated an AI-enabled electrocardiogram (ECG) system's ability to identify hospitalized patients at risk of death, demonstrating its effectiveness in reducing mortality by enhancing the rapid response systems (RRS) through real-time alerts and risk stratification.

30 Apr 2024

Garvan Institute and Illumina collaborate to transform the treatment of complex diseases

Illumina, a global genomics and human health company, has partnered with the Garvan Institute of Medical Research's TenK10K project to help transform the treatment of complex diseases, starting with autoimmune diseases, with a joint investment of $27 million AUD.

30 Apr 2024

New monoclonal antibody vaccine slashes malaria risk in children

A recent study demonstrates that the monoclonal antibody-based vaccine L9LS is safe for children aged 6 to 10 and significantly reduces the risk of malaria infection and clinical symptoms by 70% and 77%, respectively.

30 Apr 2024

Deciphering the role of Th2-multipotent progenitor cells in chronic allergic inflammation

Currently, most therapies for allergic diseases require lifelong treatment. Allergic reactions, characterized by ongoing (type 2) inflammation in response to chronic antigen exposure, underlie many chronic diseases in humans, including asthma, atopic dermatitis, ulcerative colitis and more.

30 Apr 2024

Measles and rubella vaccine delivered via microarray patch shows promising results

The phase 1/2 randomized trial compared results from the measles and rubella vaccine delivered by a microarray patch, a small sticking plaster-like device with an array of microscopic projections that painlessly penetrate the skin and deliver the vaccine, or by conventional injection with a needle and syringe.

29 Apr 2024

STRONG STAR Consortium awarded $17M for traumatic brain injury and psychological health research

In a recent round of grant awards, the STRONG STAR Consortium based at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) was selected by the U.S. Department of Defense for a total of $17 million in funding to launch eight new research projects focused on traumatic brain injury and psychological health.

29 Apr 2024

Georgetown study raises concerns over aspirin's role in breast cancer treatment

A new study examining the role of aspirin in breast cancer treatment reveals critical issues related to health equity and aging that have broad implications for cancer and other disease intervention trials, say researchers from Georgetown University's Lombardi Comprehensive Cancer Center.

29 Apr 2024

Assessing newborn nursing mechanics with modified pacifier technology and AI algorithms

A modified pacifier and AI algorithms to analyze the data it produces could determine if newborns are learning the proper mechanics of nursing, a recent study shows.

29 Apr 2024

Study reveals how genetic changes in SCN2A gene impact autism and epilepsy

A genetic change or variant in a gene called SCN2A is a known cause of infantile seizures, autism spectrum disorder and intellectual disability, as well as a wide range of other moderate-to-profound impairments in mobility, communication, eating and vision.

26 Apr 2024

Single dose of malaria monoclonal antibody 77% effective in children, trial in Mali shows

One injected dose of an experimental malaria monoclonal antibody was 77% effective against malaria disease in children in Mali during the country's six-month malaria season, according to the results of a mid-stage clinical trial.

26 Apr 2024

Japanese researchers test cardiac spheroids for heart regeneration in monkeys

Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function.

26 Apr 2024

First UK real-world study shows promise for sacituzumab govitecan in metastatic breast cancer

The real-world safety and efficacy of sacituzumab govitecan (SG) against metastatic triple-negative breast cancer.

26 Apr 2024

AI in healthcare shows promise in trials but needs real-world testing to ensure effectiveness

A comprehensive study published in The Lancet Digital Health analyzed the efficacy and challenges of AI in clinical settings, revealing a critical need for real-world testing and diverse research methodologies to ensure AI's reliable integration into healthcare.

25 Apr 2024

Insilico Medicine's AI-designed drug ISM3412 receives FDA IND approval

Clinical stage artificial intelligence (AI)-driven drug discovery company Insilico Medicine announces that it has received approval from the U.S. Food and Drug Administration for its Investigational New Drug application for ISM3412, a small molecule inhibitor of MAT2A for the potential treatment of MTAP deleted cancers designed with Insilico's generative AI platform.

25 Apr 2024

Genetic variants linked to Parkinson's risk from pesticide exposure

A new UCLA Health study found certain genetic variants could help explain how long-term pesticide exposure could increase the risk of Parkinson's disease.

25 Apr 2024

Reduction of prenatal depression associated with higher full-term birth rates

The effect of lowering prenatal mother depression on gestational duration.

25 Apr 2024

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

In a landmark study, an international consortium led by researchers at Children's Hospital of Philadelphia (CHOP) published the final results of a key clinical trial of the gene therapy CASGEVY (exagamglogene autotemcel) for the treatment of sickle cell disease in patients 12 years and older with recurrent vaso-occlusive crises (VOCs).

24 Apr 2024

Novel immunotherapy shows promise for high-risk sarcomas: HEROS 2.0 trial results published

Researchers at Texas Children’s Cancer Center and the Center for Cell and Gene Therapy at Baylor College of Medicine, Texas Children’s Hospital and Houston Methodist published results of a phase I clinical trial of a novel immunotherapy for high-risk sarcomas in the journal Nature Cancer.

24 Apr 2024

Study links poor heart health in Black women to midlife cognitive decline

A new study has found that Black women with poor cardiovascular health may face an elevated risk of early signs of cognitive decline in midlife.

24 Apr 2024

Better cardiovascular health among middle-aged Black women linked to less decline in cognition

Better heart health was linked to less decline in mental processing speed and cognition among middle-aged Black women, although not among middle-aged white women, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

24 Apr 2024

1
2
3
4
...
1055
Next

Clinical Trial News and Research

AI-enabled ECG system significantly reduces hospital mortality rates by identifying at-risk patients

Garvan Institute and Illumina collaborate to transform the treatment of complex diseases

New monoclonal antibody vaccine slashes malaria risk in children

Deciphering the role of Th2-multipotent progenitor cells in chronic allergic inflammation

Measles and rubella vaccine delivered via microarray patch shows promising results

STRONG STAR Consortium awarded $17M for traumatic brain injury and psychological health research

Georgetown study raises concerns over aspirin's role in breast cancer treatment

Assessing newborn nursing mechanics with modified pacifier technology and AI algorithms

Study reveals how genetic changes in SCN2A gene impact autism and epilepsy

Single dose of malaria monoclonal antibody 77% effective in children, trial in Mali shows

Japanese researchers test cardiac spheroids for heart regeneration in monkeys

First UK real-world study shows promise for sacituzumab govitecan in metastatic breast cancer

AI in healthcare shows promise in trials but needs real-world testing to ensure effectiveness

Insilico Medicine's AI-designed drug ISM3412 receives FDA IND approval

Genetic variants linked to Parkinson's risk from pesticide exposure

Reduction of prenatal depression associated with higher full-term birth rates

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

Novel immunotherapy shows promise for high-risk sarcomas: HEROS 2.0 trial results published

Study links poor heart health in Black women to midlife cognitive decline

Better cardiovascular health among middle-aged Black women linked to less decline in cognition

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest Life Science News