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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Natural compounds in gut microbiome show promise for inflammation treatment

Researchers at the University of Toronto have found naturally occurring compounds in the gut that can be harnessed to reduce inflammation and other symptoms of digestive issues.

3 May 2024

Father's gut health in mice linked to offspring's well-being, study finds

Study shows that disruptions in the gut microbiota of male mice can negatively affect offspring health, leading to growth issues and increased mortality. However, restoring the father's microbiota before conception may prevent these problems.

2 May 2024

Central and peripheral clock synchronization vital for optimal tissue function

Discovered in the 1970s, circadian clocks are essential for the regulation of biological time in most cells in the human body.

2 May 2024

Gut microbiome study challenges established cancer biomarkers, identifies new bacterial links to colorectal cancer

Study identified that several specific bacterial species were significantly associated with colorectal cancer, challenging previous assumptions about established biomarkers once adjusted for important covariates.

1 May 2024

Study reveals survival benefit from genome-matched cancer treatments in rural Maine

In 2016, The Jackson Laboratory (JAX), a National Cancer Institute-designated Cancer Center and at the forefront of cancer research, launched the Maine Cancer Genomics Initiative (MCGI) to bring the latest progress in cancer care to rural Maine patients.

1 May 2024

Cancer-like cells found in clogged arteries aggravate atherosclerosis

Columbia University researchers have found cells inside clogged arteries share similarities with cancer and aggravate atherosclerosis, raising the possibility that anticancer drugs could be used to treat atherosclerosis and prevent heart attacks.

1 May 2024

Electric pulses boost gene therapy uptake in liver cells

In an effort to improve delivery of costly medical treatments, a team of researchers in electrical engineering at the University of Wisconsin–Madison has developed a stimulating method that could make the human body more receptive to certain gene therapies.

30 Apr 2024

Gut bacteria and urinary infections linked, offering new angles for treatment

A study in eClinicalMedicine explores the relationship between gut microbiota, urinary tract colonization, and recurrent urinary tract infections (rUTI), suggesting the cross-habitation of uropathogenic E. coli as a significant mechanism in rUTI recurrence.

30 Apr 2024

New biomarker predicts immunotherapy response in gastrointestinal cancers

Despite significant progress in treating gastrointestinal (GI) cancers through surgical resection, chemotherapy, radiotherapy, and targeted therapy, the objective response rate (ORR) for immune checkpoint inhibitor (ICI) therapy remains low.

30 Apr 2024

New approach to inhibit strep’s DNA-cleaving enzymes

An entirely new approach to inhibiting DNA-cleaving enzymes works through the aggregation of an otherwise non-toxic molecule.

30 Apr 2024

RNA editing using CRISPRs shows promise for genetic disease treatment

A team at Montana State University published research this week that shows how RNA, the close chemical cousin to DNA, can be edited using CRISPRs.

29 Apr 2024

SCA4 genetic breakthrough: Unveiling the cause of a devastating neurological disease

Some families call it a trial of faith. Others just call it a curse. The progressive neurological disease known as spinocerebellar ataxia 4 (SCA4) is a rare condition, but its effects on patients and their families can be severe.

29 Apr 2024

New study reveals potential cellular mechanism behind cognitive decline in Alzheimer's

Researchers have developed a robust method for identifying rare brain neurons that re-enter the cell cycle, offering insights into their role in cognitive disorders such as Alzheimer's disease.

28 Apr 2024

Leveraging CRISPR/Cas technology to address antimicrobial resistance

In the second new research review on this subject, Assistant Prof. Ibrahim Bitar, Department of Microbiology, Faculty of Medicine and University Hospital in Plzen, Charles University in Prague, Plzen, Czech Republic, will give an overview of the molecular biology of CRISPR technology in explaining how it can used to tackle antimicrobial resistance.

26 Apr 2024

Ohio State study reveals bacterial defense mechanism against phages

One of the many secrets to bacteria's success is their ability to defend themselves from viruses, called phages, that infect bacteria and use their cellular machinery to make copies of themselves.

26 Apr 2024

Machine learning-powered robot streamlines genetic research process

University of Minnesota Twin Cities researchers have constructed a robot that uses machine learning to fully automate a complicated microinjection process used in genetic research.

26 Apr 2024

New national center at Penn State aims to advance understanding of complex biological systems

A $20 million grant from the U.S. National Science Foundation (NSF) will support the establishment and operation of the National Synthesis Center for Emergence in the Molecular and Cellular Sciences (NCEMS) at Penn State.

25 Apr 2024

Insilico Medicine's AI-designed drug ISM3412 receives FDA IND approval

Clinical stage artificial intelligence (AI)-driven drug discovery company Insilico Medicine announces that it has received approval from the U.S. Food and Drug Administration for its Investigational New Drug application for ISM3412, a small molecule inhibitor of MAT2A for the potential treatment of MTAP deleted cancers designed with Insilico's generative AI platform.

25 Apr 2024

Does reproduction influence epigenetic aging in younger women?

The association between reproduction and biological aging based on epigenetic clocks.

25 Apr 2024

Genetics studies have a diversity problem that researchers struggle to fix

When he recently walked into the dental clinic at the Medical University of South Carolina donning a bright-blue pullover with "In Our DNA SC" embroidered prominently on the front, Lee Moultrie said, two Black women stopped him to ask questions.

25 Apr 2024