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New mechanism discovered to weaken pseudomonas aeruginosa virulence

The opportunistic bacterial pathogen Pseudomonas aeruginosa is dangerous due to its resistance to multiple antibiotics.

14 May 2024

Study reveals unintended consequences of antibiotic choice in sepsis treatment

In emergency rooms and intensive care units across the country, clinicians make split-second decisions about which antibiotics to give a patient when a life-threatening infection is suspected.

14 May 2024

Zika virus-specific synthetic molecule can differentiate between prior infections with different flaviviruses

A newly discovered Zika virus-specific synthetic molecule is capable of differentiating Zika-immune patient samples from samples of patients previously infected with the related dengue virus.

14 May 2024

What is the ‘immune self,’ and how can this concept benefit immunological research?

A perspective review discusses the concept of the 'immune self' and how adaptive immune responses are influenced by self-similarity. The study emphasizes advances and challenges in defining self-similarity and its impact on immunological research.

13 May 2024

Identification of pathogenicity-associated milRNAs in Fusarium oxysporum f. sp. cubense

Fusarium oxysporum f. sp. cubense (Foc) is a typical soil-borne fungus that causes Fusarium wilt by infecting the roots and blocking the vascular tissues of host banana, and threatens the global banana production.

10 May 2024

Surprising study suggests urbanization might reduce global infectious disease risk

A comprehensive meta-analysis reveals that biodiversity loss, climate change, and chemical pollution significantly increase global infectious disease risk, while urbanization may decrease it.

10 May 2024

UT Health San Antonio leads effort for developing oral vaccine against chlamydia

The study of a novel oral vaccine that could protect against chlamydia infection has been awarded approximately $11 million in National Institutes of Health funding over five years through a cooperative agreements research project grant, known as a U01 grant.

9 May 2024

Novel bispecific antibodies show promise against evolving SARS-CoV-2 variants

Researchers developed bispecific antibodies targeting both the N-terminal and receptor binding domains of SARS-CoV-2, demonstrating significant neutralization across various Omicron variants, suggesting potential for new COVID-19 treatments.

9 May 2024

New Quartet nanocage vaccine shows promise against coronavirus variants

Researchers have developed a novel vaccination approach using Quartet nanocages that display receptor-binding domains (RBDs) from different sarbecoviruses, showing enhanced immune responses and potential protection against diverse coronavirus strains including SARS-CoV-2 and its variants.

8 May 2024

Wayne State University researcher receives NIH grant to tackle diabetic eye infections

Fu-Shin Yu, Ph.D., professor of ophthalmology, visual and anatomical sciences in the Wayne State University School of Medicine, received an award from the National Eye Institute of the National Institutes of Health for his study aiming to reverse the adverse effects of diabetes on eyesight.

7 May 2024

Innovative methodologies for investigating intestinal mucus properties and response

As much as we might not want to think about it, mucus is everywhere in our bodies. It coats our airways and our digestive systems and serves as a first line of defense against pathogens, a habitat for our microbiomes, and a conveyor belt for our insides to keep everything moving smoothly.

7 May 2024

New vaccine technology provides protection against broad range of coronaviruses in mice

Researchers have developed a new vaccine technology that has been shown in mice to provide protection against a broad range of coronaviruses with potential for future disease outbreaks - including ones we don't even know about.

6 May 2024

Researchers review current evidence on Candida auris, an emerging multidrug-resistant yeast

Researchers discuss current evidence on Candida auris, an emerging multidrug-resistant yeast.

6 May 2024

Novel vaccine approach targets AML and other blood cancers

Acute myeloid leukemia (AML) is a type of blood cancer that forms in the soft marrow of the bones, typically attacking cells that would otherwise form the key component of the body's immunodefense system, white blood cells.

3 May 2024

Bird flu is bad for poultry and dairy cows. It’s not a dire threat for most of us — yet.

Headlines are flying after the Department of Agriculture confirmed that the H5N1 bird flu virus has infected dairy cows around the country.

3 May 2024

Research uncovers Blautia bacteria's crucial role in gut health and disease protection

A low-fiber “Western diet” causes damage to the protective mucus barrier in the gut, and such damage can increase the risk of inflammation and infection.

29 Apr 2024

Study rethinks immune system strategies to boost vaccine effectiveness

A recent Cell journal review explores key immunological assumptions to enhance our understanding of vaccine design, autoimmune responses, and immune system pathology, aiming to refine intervention strategies and theoretical frameworks in immunology.

28 Apr 2024

Putting genomic surveillance of pathogens at the forefront of future pandemic preparedness

The Covid-19 pandemic turned the world upside down. In fighting it, one of our most important weapons was genomic surveillance, based on whole genome sequencing, which collects all the genetic data of a given microorganism.

25 Apr 2024

Meta-analysis reveals drivers of antibiotic resistance in infants

A meta-analysis of genetic studies analyzing the microbiota (bacteria in the gut) of 1,275 infants from 10 countries finds that cesarean delivery and antibiotic use are driving the increase of antibiotic resistance genes load among infants, according to new research being presented at this year's ESCMID Global Congress (formerly ECCMID) in Barcelona, Spain (27-30 April).

24 Apr 2024

Innovative peptide-based hydrogel therapy for virus prevention

Vaccines remain the gold standard of protection against dangerous pathogens, but take considerable time and vast resources to develop.

23 Apr 2024

Pathogen News and Research

New mechanism discovered to weaken pseudomonas aeruginosa virulence

Study reveals unintended consequences of antibiotic choice in sepsis treatment

Zika virus-specific synthetic molecule can differentiate between prior infections with different flaviviruses

What is the ‘immune self,’ and how can this concept benefit immunological research?

Identification of pathogenicity-associated milRNAs in Fusarium oxysporum f. sp. cubense

Surprising study suggests urbanization might reduce global infectious disease risk

UT Health San Antonio leads effort for developing oral vaccine against chlamydia

Novel bispecific antibodies show promise against evolving SARS-CoV-2 variants

New Quartet nanocage vaccine shows promise against coronavirus variants

Wayne State University researcher receives NIH grant to tackle diabetic eye infections

Innovative methodologies for investigating intestinal mucus properties and response

New vaccine technology provides protection against broad range of coronaviruses in mice

Researchers review current evidence on Candida auris, an emerging multidrug-resistant yeast

Novel vaccine approach targets AML and other blood cancers

Bird flu is bad for poultry and dairy cows. It’s not a dire threat for most of us — yet.

Research uncovers Blautia bacteria's crucial role in gut health and disease protection

Study rethinks immune system strategies to boost vaccine effectiveness

Putting genomic surveillance of pathogens at the forefront of future pandemic preparedness

Meta-analysis reveals drivers of antibiotic resistance in infants

Innovative peptide-based hydrogel therapy for virus prevention

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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