Gene News and Research

Latest Gene News and Research

Study examines association between neighborhood disadvantage and DNA methylation in brain tissue

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, "The association between neighborhood deprivation and DNA methylation in an autopsy cohort."

9 May 2024

Understanding aging through stochastic changes in cells

Aging clocks can measure the biological age of humans with high precision. Biological age can be influenced by environmental factors such as smoking or diet, thus deviating from the chronological age that is calculated using the date of birth.

9 May 2024

New modular epigenome editing platform sheds light on gene regulation mechanisms

Understanding how genes are regulated at the molecular level is a central challenge in modern biology.

9 May 2024

Researchers enhance CAR-T cells to target solid tumors

Researchers at the National Cancer Institute-designated Montefiore Einstein Comprehensive Cancer Center (MECCC) have shown that a breakthrough therapy for treating blood cancers can be adapted to treat solid tumors-;an advance that could transform cancer treatment.

8 May 2024

Research offers new insight into the causes of spina bifida

A group of researchers at the University of California San Diego School of Medicine led an investigation that offers new insight into the causes of spina bifida, the most common structural disorder of the human nervous system.

8 May 2024

New clinical guideline released for effectively managing individuals with hypertrophic cardiomyopathy

The American College of Cardiology (ACC) and the American Heart Association (AHA) today released a new clinical guideline for effectively managing individuals diagnosed with hypertrophic cardiomyopathy (HCM).

8 May 2024

Molecular pathology of Schaaf-Yang syndrome: Insights into MAGEL2 gene mutations and truncated proteins

Mutations in the MAGEL2 gene, which cause Schaaf-Yan syndrome (SYS) —an ultra-rare disease that affects neuronal and cognitive development— generate truncated, non-functional proteins that tend to accumulate in the cell nucleus.

8 May 2024

Clinical trial shows CRISPR gene editing has exciting potential to treat a rare form of blindness

A recent study published in The New England Journal of Medicine investigated the potential use of gene editing to correct a congenital retinal degeneration called CEP290 that causes early-onset vision loss.

8 May 2024

Intermittent fasting halts liver disease progression and reduces cancer risk

Fatty liver disease often leads to chronic liver inflammation and can even result in liver cancer. Scientists from the German Cancer Research Center (DKFZ) and the University of Tübingen have now shown in mice that intermittent fasting on a 5:2 schedule can halt this development.

8 May 2024

Gene linked to intellectual disability can regulate learning and memory

A gene previously linked to intellectual disability has been found to regulate learning and memory in mice.

8 May 2024

APOE4 gene linked to early onset Alzheimer's, target for therapeutic intervention

A study published in Nature Medicine delineates how APOE4 homozygosity distinctly accelerates Alzheimer's disease pathology and biomarkers from the age of 55, suggesting a unique form of the disease and a potential focus for targeted therapies.

8 May 2024

AI-driven model identifies potent cancer-killing immune cells for personalized immunotherapy

Using artificial intelligence, Ludwig Cancer Research scientists have developed a powerful predictive model for identifying the most potent cancer killing immune cells for use in cancer immunotherapies.

7 May 2024

New PET imaging agent shows promise in visualizing lesions in clear cell renal cell cancer patients

A novel investigational PET imaging agent can rapidly and accurately visualize lesions in clear cell renal cell cancer (ccRCC) patients according to new research published in the May issue of The Journal of Nuclear Medicine.

7 May 2024

Exploring associations between NMR-measured biomarkers and accelerated aging in cardiac catheterization patients

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, "Associations among NMR-measured inflammatory and metabolic biomarkers and accelerated aging in cardiac catheterization patients."

7 May 2024

Unraveling the complex pathology of gastric cancer: TP53 loss and extrinsic risk factors

GC ranks as the fifth most common and fourth deadliest cancer worldwide, presenting significant health challenges, particularly in China where it is most prevalent and accounts for nearly half of newly diagnosed and death cases.

7 May 2024

New study highlights sharp rise in exposures to synthetic cannabis products among youth

A sharp rise in exposures to synthetic cannabis products among youth -; some leading to hospitalization -; highlights the need for increased education around the dangers of exposure and increased focus on safe storage and packaging, according to pediatricians and researchers at Nationwide Children's Hospital and the Central Ohio Poison Center.

7 May 2024

Broken String Biosciences and the Francis Crick Institute collaborate to advance ALS research

Partnership to expand applications of DNA break-mapping technology and advance understanding of genomic instability in development of the neurodegenerative disease amyotrophic lateral sclerosis.

From Broken String Biosciences 7 May 2024

Vitamin D receptor polymorphism found to influence COVID-19 severity

Researchers compared SNPs in the vitamin D receptor (VDR) gene between mild and severe COVID-19 patients.

7 May 2024

Neural circuits revealed as key regulators in body's immune response, study finds

A recent study in Nature reveals how specific neural circuits within the body-brain axis regulate immune responses, highlighting potential new therapeutic approaches for immune disorders.

6 May 2024

Rutgers scientists create CRISPR-edited mice to study the neurobiology of Tourette disorder

In research that may be a step forward toward finding personalized treatments for Tourette disorder, scientists at Rutgers University–New Brunswick have bred mice that exhibit some of the same behaviors and brain abnormalities seen in humans with the disorder.

6 May 2024

Gene News and Research

Latest Gene News and Research

Study examines association between neighborhood disadvantage and DNA methylation in brain tissue

Understanding aging through stochastic changes in cells

New modular epigenome editing platform sheds light on gene regulation mechanisms

Researchers enhance CAR-T cells to target solid tumors

Research offers new insight into the causes of spina bifida

New clinical guideline released for effectively managing individuals with hypertrophic cardiomyopathy

Molecular pathology of Schaaf-Yang syndrome: Insights into MAGEL2 gene mutations and truncated proteins

Clinical trial shows CRISPR gene editing has exciting potential to treat a rare form of blindness

Intermittent fasting halts liver disease progression and reduces cancer risk

Gene linked to intellectual disability can regulate learning and memory

APOE4 gene linked to early onset Alzheimer's, target for therapeutic intervention

AI-driven model identifies potent cancer-killing immune cells for personalized immunotherapy

New PET imaging agent shows promise in visualizing lesions in clear cell renal cell cancer patients

Exploring associations between NMR-measured biomarkers and accelerated aging in cardiac catheterization patients

Unraveling the complex pathology of gastric cancer: TP53 loss and extrinsic risk factors

New study highlights sharp rise in exposures to synthetic cannabis products among youth

Broken String Biosciences and the Francis Crick Institute collaborate to advance ALS research

Vitamin D receptor polymorphism found to influence COVID-19 severity

Neural circuits revealed as key regulators in body's immune response, study finds

Rutgers scientists create CRISPR-edited mice to study the neurobiology of Tourette disorder

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut