The statement 'Nevertheless, viral detection was markedly lower at four months, thus suggesting a slow but adequate viral clearance.' was not made by the study authors, nor is it supported by their findings. Declining viral titers after the acute--aka unregulated--phase are to be expected even in instances where the infection is chronic. If anything, the perturbation of cholesterol metabolism and downregulation of Complement described in vascular tissue samples are suggestive of niche modulation by an ongoing infection.