Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Novel therapy harnesses stem cell-derived exosomes for diabetic wound healing

Researchers unveiled a novel therapy for diabetic wound healing. This research highlights the use of exosomal miR-4645-5p from hypoxic bone marrow mesenchymal stem cells (BMSCs) to significantly enhance wound healing by promoting keratinocyte autophagy.

20 Feb 2024

Researchers develop artificial cell environment to promote nerve regeneration

Injuries in the central nervous system heal poorly because cavities scar. Researchers hope to remedy this problem by filling the cavities in such a way that stem cells feel comfortable in them.

20 Feb 2024

Researchers develop new way to make vegan food more appetizing

Vegan food is often sidestepped due to its rubbery consistency. Food technology researchers at Lund University in Sweden have now developed a way to make vegan food more appetizing by using new combinations of raw materials.

16 Feb 2024

City of Hope cures oldest person of blood cancer and achieves HIV remission

City of Hope, one of the largest cancer research and treatment organizations in the United States, treated the oldest person to be cured of a blood cancer and then achieve remission for HIV after receiving a blood stem cell transplant from a donor with a rare genetic mutation.

15 Feb 2024

Breaking through new research barriers with iPSC technology

In this interview, we speak to Keith Olson and Coby Carlson from Fujifilm Cellular Dynamics about their iPSC technology.

From FUJIFILM Cellular Dynamics 15 Feb 2024

Researchers discover new mechanism of action between the nutrient adaptation of intestinal stem cells and aging

Researchers used an organ-wide approach to quantitatively analyze cell number, size, and identity regulation upon nutrient-induced tissue adaptation of the Drosophila midgut.

15 Feb 2024

New epigenetic clocks distinguish aging causes and effects

What causes us to age? New "clocks" developed by researchers may help point to the answers. Investigators from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, unveil a new form of epigenetic clock – a machine learning model designed to predict biological age from DNA structure.

14 Feb 2024

Study finds interleukin-24 enhances CAR-T cell therapy's effectiveness against cancer stem cells

The effect of Interleukin-24 (IL-24) on CSCs and CAR-T cell therapy.

14 Feb 2024

Magnesium's pivotal role in slowing aging's impact

Review highlights magnesium's critical role in mitigating aging hallmarks, including telomere attrition, genomic instability, epigenetic alterations, loss of proteostasis, mitochondrial dysfunction, cellular senescence, and stem cell exhaustion, suggesting that maintaining adequate magnesium levels could support healthy aging.

13 Feb 2024

Researchers uncover new mechanism of action between nutrient adaptation of intestinal stem cells and aging

The capacity of intestinal stem cells to maintain cellular balance in the gut decreases upon aging.

12 Feb 2024

Rucaparib and its major metabolite exhibit differential biological activity and synergy

Once they enter the body, drugs, apart from carrying out their therapeutic function, are biochemically transformed by the action of the metabolic machinery, a process that facilitates their expulsion.

9 Feb 2024

Study advances search for a blood test to identify disease-associated changes in the brain

Researchers in a Johns Hopkins Children's Center-led study that used genetic material from human blood and lab-grown brain cells say they have made progress in developing a blood test to identify disease-associated changes in the brain specifically linked to postpartum depression and other psychiatric and neurological disorders.

8 Feb 2024

Tiny device could help improve safety, effectiveness of cell therapy for spinal cord injury patients

A tiny device built by scientists at MIT and the Singapore-MIT Alliance for Research and Technology could be used to improve the safety and effectiveness of cell therapy treatments for patients suffering from spinal cord injuries.

7 Feb 2024

Burn injury disrupts the intestinal mucus barrier and alters gut microbiota, study reveals

On a study (doi:10.1093/burnst/tkad056) published in the journal Burns & Trauma, researchers employed a combination of techniques to analyze the effects of burn injury on the gut microbiota and mucus barrier in mice.

6 Feb 2024

Bioprinting breakthrough: Tech platform creates 3D neural tissues in which neurons and glia connect

Researchers produced 3D bioprinted human brain tissues, allowing for the creation of functioning neural networks that could simulate network activity in normal and pathological situations.

6 Feb 2024

Xist lncRNA identified as key trigger in female-biased autoimmune diseases

Researchers uncover that the Xist ribonucleoprotein complex, unique to females, is a key driver of sex-biased autoimmunity, offering new insights into autoimmune disorders' higher prevalence in women.

4 Feb 2024

CRISPR-Cas9 gene-editing tool repairs defective T cells to treat rare hereditary disease

Some hereditary genetic defects cause an exaggerated immune response that can be fatal. Using the CRISPR-Cas9 gene-editing tool, such defects can be corrected, thus normalizing the immune response, as researchers led by Klaus Rajewsky from the Max Delbrück Center now report in "Science Immunology."

2 Feb 2024

Stem Cells News and Research

Further Reading

Novel therapy harnesses stem cell-derived exosomes for diabetic wound healing

Researchers develop artificial cell environment to promote nerve regeneration

Researchers develop new way to make vegan food more appetizing

City of Hope cures oldest person of blood cancer and achieves HIV remission

Breaking through new research barriers with iPSC technology

Researchers discover new mechanism of action between the nutrient adaptation of intestinal stem cells and aging

New epigenetic clocks distinguish aging causes and effects

Study finds interleukin-24 enhances CAR-T cell therapy's effectiveness against cancer stem cells

Magnesium's pivotal role in slowing aging's impact

Researchers uncover new mechanism of action between nutrient adaptation of intestinal stem cells and aging

Rucaparib and its major metabolite exhibit differential biological activity and synergy

Study advances search for a blood test to identify disease-associated changes in the brain

Tiny device could help improve safety, effectiveness of cell therapy for spinal cord injury patients

Burn injury disrupts the intestinal mucus barrier and alters gut microbiota, study reveals

Bioprinting breakthrough: Tech platform creates 3D neural tissues in which neurons and glia connect

Xist lncRNA identified as key trigger in female-biased autoimmune diseases

CRISPR-Cas9 gene-editing tool repairs defective T cells to treat rare hereditary disease

Phase II clinical trial evaluates the safety and efficacy of a Muse cell-based product in patients with ALS

Is there an association between vitamin D, immunocompetence, and aging?

Researchers discover new class of compound that targets cancer stem cells

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