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Study reveals how genetic changes in SCN2A gene impact autism and epilepsy

A genetic change or variant in a gene called SCN2A is a known cause of infantile seizures, autism spectrum disorder and intellectual disability, as well as a wide range of other moderate-to-profound impairments in mobility, communication, eating and vision.

26 Apr 2024

Ketone supplement boosts efficacy of prostate cancer immunotherapy

Adding a pre-ketone supplement -; a component of a high-fat, low-carb ketogenic diet -; to a type of cancer therapy in a laboratory setting was highly effective for treating prostate cancer, researchers from the University of Notre Dame found.

26 Apr 2024

Novel SYBR green-based RT-qPCRs developed for lone star virus detection

Announcing a new article publication for Zoonoses journal. Lone Star virus (LSV) is a newly characterized arbovirus with pathogenic potential.

26 Apr 2024

WHO data reveals extensive antibiotic overuse during COVID-19 pandemic

New evidence from the World Health Organization shows the extensive overuse of antibiotics during COVID-19 pandemic worldwide, which may have exacerbated "silent" spread of antimicrobial resistance (AMR).

26 Apr 2024

Achieving and maintaining ISO 27001 and BS 10012 certifications

In this interview, Dr. Fu Wei, Director of Quality Management Department at BGI Genomics talks to AZoMedical about achieving and maintaining ISO 27001 and BS 10012 certifications.

From BGI Genomics 26 Apr 2024

Putting genomic surveillance of pathogens at the forefront of future pandemic preparedness

The Covid-19 pandemic turned the world upside down. In fighting it, one of our most important weapons was genomic surveillance, based on whole genome sequencing, which collects all the genetic data of a given microorganism.

25 Apr 2024

Bivalent COVID-19 vaccine boosts immunity but needs to be updated

A major bivalent COVID-19 vaccine induces production of neutralizing antibodies against the coronavirus that circulated at the start of the pandemic as well as subvariants of omicron, albeit less abundantly, according to a Brazilian study reported in the Journal of Medical Virology.

25 Apr 2024

Machine learning system offers new hope for diagnosis of rare genetic disorders

Diagnosing rare Mendelian disorders is a labor-intensive task, even for experienced geneticists. Investigators at Baylor College of Medicine are trying to make the process more efficient using artificial intelligence.

25 Apr 2024

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Whether human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could heal luminal ulcers in Crohn’s disease.

25 Apr 2024

CASGEVY gene therapy eliminates vaso-occlusive crises in sickle cell patients

In a landmark study, an international consortium led by researchers at Children's Hospital of Philadelphia (CHOP) published the final results of a key clinical trial of the gene therapy CASGEVY (exagamglogene autotemcel) for the treatment of sickle cell disease in patients 12 years and older with recurrent vaso-occlusive crises (VOCs).

24 Apr 2024

Prostaglandin E2: The culprit behind tumor immune evasion

Tumors actively prevent the formation of immune responses by so-called cytotoxic T cells, which are essential in combating cancer. Researchers at the Technical University of Munich (TUM) and the Ludwig-Maximilians-Universität München (LMU) Hospital have now uncovered for the first time how this exactly happens.

24 Apr 2024

Brain dynamics and BMI linked to dieting success, study finds

Research reveals that individuals with higher BMI and extensive brain modifications during diet decisions tend to have lower success in diet modification, suggesting the impact of neural plasticity and BMI on diet adherence.

23 Apr 2024

Emulsifiers in processed foods may be linked to increased risk of type 2 diabetes

In Europe and North America, 30 to 60% of dietary energy intake in adults comes from ultra-processed foods.

23 Apr 2024

$4.8 million grant supports research on TDP-43 misfolding in neurodegenerative diseases

A new $4.8 million grant will support researchers from Indiana University School of Medicine and the Medical Research Council Laboratory of Molecular Biology to study how human neurodegenerative diseases are affected by the misfolding of the protein TDP-43.

23 Apr 2024

Study identifies molecular pathway in liver cancer development

As a malignant disease of the liver cells, hepatocellular carcinoma (HCC) is one of the main causes of cancer-related deaths.

23 Apr 2024

Researchers aim to use AI for early screening and prognosis of Dry Eye Disease

Dry Eye Disease (DED) is one of the more common eye diseases, affecting up to 30% of the world's population.

23 Apr 2024

US study links extended sitting and lack of coffee to higher death rates

The independent and combined effects of daily sedentary times and coffee consumption on cardiovascular disease.

23 Apr 2024

Study discovers hidden mechanism behind rapid COVID variants

The SARS-CoV-2 virus that causes COVID has the unsettling ability of often generating variants of itself. Other viruses also mutate, but as SARS-CoV-2 quickly spread throughout the entire human population during the pandemic, killing millions, the virus' dynamic evolution posed a serious problem: it repeatedly challenged our bodies' immune response fighting the virus and hindered the process of getting updated vaccines ready.

23 Apr 2024

New technique tracks drug use through smartphones

A simple and convenient method to collect drug use data from the surface of a smartphone is revealed for the first time in a new study published in De Gruyter's Clinical Chemistry and Laboratory Medicine. By helping clinicians understand what drugs people are taking in certain contexts, the research could protect public health and improve the treatment of patients suspected of overdosing.

23 Apr 2024

Study shows meth users have lower empathy and higher aggression, ecstasy users show normal empathy but more impulsive aggression

A study in the European Neuropsychopharmacology journal finds that methamphetamine users show lower empathy and higher aggression, whereas ecstasy (MDMA) users exhibit increased impulsive aggression but normal empathy levels.

23 Apr 2024