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Study shows synergistic effects of time-restricted eating and high-intensity functional training on health

Combining time-restricted eating with high-intensity functional training may improve body composition and cardiometabolic parameters more than either alone, according to a study published May 1, 2024 in the open-access journal PLOS ONE by Ranya Ameur and Rami Maaloul from the University of Sfax, Tunisia, and colleagues.

2 May 2024

New drug candidate reverses obesity in mice by transforming liver metabolism

A mitochondrial transcription inhibitor (IMT) shifted metabolism in high-fat diet mice toward fatty acid oxidation, leading to weight loss, reduced liver fat, and improved glucose tolerance.

1 May 2024

Research offers hope to millions of people with complex regional pain syndrome

Complex Regional Pain Syndrome (CRPS) is a chronic and debilitating pain disorder, typically considered lifelong with limited treatment options.

30 Apr 2024

Unlocking the mechanisms of pluripotent cell's fate determination

As embryos, all complex organisms are partially made up of pluripotent stem cells, a term for cells that have the capacity to differentiate into any kind of cell: nerve cells, muscle cells, blood cells, skin cells, and the like.

29 Apr 2024

Japanese researchers test cardiac spheroids for heart regeneration in monkeys

Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function.

26 Apr 2024

Low vitamin D tied to belly fat and weak muscles in women

Low vitamin D in women is linked to more belly fat and lower muscle mass. The study suggests using waist-to-height ratio and muscle mass index to assess health risks.

25 Apr 2024

New system personalizes chemotherapy doses for cancer patients

When cancer patients undergo chemotherapy, the dose of most drugs is calculated based on the patient's body surface area. This is estimated by plugging the patient's height and weight into an equation, dating to 1916, that was formulated from data on just nine patients.

24 Apr 2024

Timelapse breakthrough: Scientists capture secrets of early embryonic cell division

The beginning of life is shrouded in mystery. While the intricate dynamics of mitosis is well-studied in the so-called somatic cells – the cells that have a specialized function, like skin and muscle cells – they remain elusive in the first cells of our bodies, the embryonic cells.

24 Apr 2024

Study unveils novel bladder cancer diagnostic model based on key mitochondrial genes

A novel diagnostic model using machine learning (ML).

24 Apr 2024

FDA approval of Anktiva heralds a new era in the treatment of BCG-unresponsive non–muscle-invasive bladder cancer

The U.S. Food and Drug Administration (FDA) has approved the immunotherapy-boosting drug N-803, which is marketed under the brand name Anktiva, to be used in combination with the immunotherapy Bacillus Calmette-Guerin (BCG) for the treatment of patients with BCG-unresponsive non–muscle-invasive bladder cancer.

23 Apr 2024

Unlocking the potential of insects as sustainable protein sources

Could insects be a viable alternative source of protein in our diets? Researchers from the University of Surrey need your help to get to the bottom of this much-debated question.

23 Apr 2024

New models improve heart disease risk prediction, especially for women

When it comes to matters of the heart, cardiovascular disease in women is underdiagnosed compared to men. A popular scoring system used to estimate how likely a person is to develop a cardiovascular disease within the next 10 years is the Framingham Risk Score. It is based on factors including age, sex, cholesterol levels, and blood pressure.

23 Apr 2024

Aster DM Healthcare reveals top foods to combat PCOS symptoms

Google searches related to Polycystic Ovary Syndrome (PCOS) reached an all-time high in April 2024 globally, indicating a growing concern and interest in understanding and managing this condition.

23 Apr 2024

Does diabetes increase the risk of long COVID?

A recent study in eClinicalMedicine assesses whether individuals with diabetes are more susceptible to developing long COVID, analyzing a UK cohort to explore the prolonged impact of SARS-CoV-2 infection in this population.

22 Apr 2024

Waist circumference-to-height ratio strongly predicts fecal incontinence

Fecal incontinence (FI), or involuntary loss of bowel control, significantly impacts quality of life and mental health for millions of adults in the U.S.

22 Apr 2024

Young mouse plasma found to reverse aging in older mice

Researchers demonstrate that small extracellular vesicles (sEVs) from young mice plasma can reverse aging effects in older mice by enhancing mitochondrial function and energy metabolism.

22 Apr 2024

Optimize postprandial glycemic control with tailored exercise prescriptions

Researchers elucidate various exercise parameters influence post-meal glucose responses in healthy and diabetic individuals.

18 Apr 2024

Universities collaborate on $15 million project investigating inflammation's role in cardiac and brain diseases

Research teams from Northwestern University Chicago Campus, University of Michigan and University of Pittsburgh will lead a $15 million project dedicated to studying inflammation's role in cardiac and brain diseases.

17 Apr 2024

Deeper sedation with propofol may improve detection of serrated polyps during colonoscopy

In patients undergoing colonoscopy to screen for colorectal cancer, deeper sedation using the anesthetic drug propofol may improve detection of "serrated" polyps -; a type of precancerous lesion that can be difficult to detect, reports a study in the Online First edition of Anesthesiology, the peer-reviewed journal of the American Society of Anesthesiologists.

17 Apr 2024

Vitamin D deficiency persists despite easy access, review suggests need for tailored supplements

Researchers in a study published in the journal Nutrients delve into the pervasive issue of vitamin D deficiency and its link to various health conditions, advocating for precision nutrition and personalized supplementation to enhance vitamin D intake and effectiveness.

17 Apr 2024