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Obesity, metabolic syndrome impact breast cancer subtypes and mortality

In the Women's Health Initiative (WHI) randomized trial, a low-fat diet reduced breast cancer mortality, especially in women with more metabolic syndrome (MetS) components (obesity, high blood pressure, elevated blood sugar, and abnormal cholesterol).

13 May 2024

Researchers discover how gut microbes influence social behavior in mice

For people with autism, constipation, diarrhea, and abdominal pain often go along with the social struggles and repetitive behaviors that define the condition.

13 May 2024

Study shows clear benefit from COVID-19 vaccination for heart failure patients

Heart failure patients who are vaccinated against COVID-19 have an 82% greater likelihood of living longer than those who are not vaccinated, according to research presented today at Heart Failure 2024, a scientific congress of the European Society of Cardiology.

13 May 2024

Bats in China found to carry novel herpesviruses, hinting at cross-species transmission dangers

Researchers in Wuhan, China, have identified new strains ofβ and γ-herpesviruses in bats. These findings reveal potential cross-species transmission risks and emphasize the need for vigilant monitoring of bat populations to prevent zoonotic diseases.

13 May 2024

Enhanced weight loss outcomes with GLP-1 analogues and bupropion/naltrexone combination

A study explores the additive effects of combining GLP-1 analog with bupropion/naltrexone on weight loss, finding potential benefits even for those initially unresponsive to monotherapy.

13 May 2024

Study sheds light on challenges faced by caregivers of children with genetic conditions

When it comes to improving the lives of children with genetic conditions, medical research often focuses solely on the children. But there is an equally important population in need of research that a faculty member at the University of Colorado Department of Medicine is highlighting -; the caregivers.

10 May 2024

Can vitamin D3 supplementation reduce COVID-19 severity?

The effectiveness of Vitamin D3 supplementation in reducing intensive care unit admissions.

10 May 2024

A previously unknown post-COVID syndrome found

Pradipta Ghosh, M.D., sat down in her office at the University of California San Diego School of Medicine and considered a request from the other side of the world.

9 May 2024

AML patients at the extremes of older age derive benefit from VEN-HMA regimen

Standard of care treatment for acute myeloid leukemia (AML) is safe and effective for adults over 80, according to a study published in Blood Neoplasia. For roughly a quarter of patients, this treatment can durably prolong survival.

9 May 2024

Higher consumption of ultra-processed foods linked to elevated mortality risk

The relationship between ultra-processed food (UPF) intake and all-cause and cause-specific death.

9 May 2024

Novel bispecific antibodies show promise against evolving SARS-CoV-2 variants

Researchers developed bispecific antibodies targeting both the N-terminal and receptor binding domains of SARS-CoV-2, demonstrating significant neutralization across various Omicron variants, suggesting potential for new COVID-19 treatments.

9 May 2024

Heightened risk of adverse neonatal outcomes from prenatal exposure to both cannabis and nicotine

A recent JAMA Network Open study found that combined prenatal use of nicotine and cannabis significantly increases risks for adverse perinatal outcomes, such as higher rates of hypertensive disease, preterm delivery, and elevated infant mortality compared to using neither or only one substance.

9 May 2024

Underdiagnosed and common: Study highlights neuropathy's hidden toll

Neuropathy, the nerve damage that causes pain and numbness in the feet and hands and can eventually lead to falls, infection and even amputation, is very common and underdiagnosed, according to a study published in the May 8, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

8 May 2024

Brain-computer interface translates ALS patient's brain activity into spoken words

Researchers successfully used a brain-computer interface to synthesize speech directly from brain activity in an ALS patient, achieving 80% word recognition accuracy by listeners, showcasing the interface's potential for aiding communication in severe speech impairments.

8 May 2024

New tool more accurately predicts an individual's 10-year risk of cardiovascular diseases

Collaborative research, led from the University of Oxford and published today in Nature Medicine, has developed a new tool called QR4 that more accurately predicts an individual's 10-year risk of cardiovascular diseases, like heart disease and stroke, particularly identifying high-risk patients that current prediction tools miss.

8 May 2024

Molecular pathology of Schaaf-Yang syndrome: Insights into MAGEL2 gene mutations and truncated proteins

Mutations in the MAGEL2 gene, which cause Schaaf-Yan syndrome (SYS) —an ultra-rare disease that affects neuronal and cognitive development— generate truncated, non-functional proteins that tend to accumulate in the cell nucleus.

8 May 2024

APOE4 gene linked to early onset Alzheimer's, target for therapeutic intervention

A study published in Nature Medicine delineates how APOE4 homozygosity distinctly accelerates Alzheimer's disease pathology and biomarkers from the age of 55, suggesting a unique form of the disease and a potential focus for targeted therapies.

8 May 2024

New Quartet nanocage vaccine shows promise against coronavirus variants

Researchers have developed a novel vaccination approach using Quartet nanocages that display receptor-binding domains (RBDs) from different sarbecoviruses, showing enhanced immune responses and potential protection against diverse coronavirus strains including SARS-CoV-2 and its variants.

8 May 2024

Rutgers scientists create CRISPR-edited mice to study the neurobiology of Tourette disorder

In research that may be a step forward toward finding personalized treatments for Tourette disorder, scientists at Rutgers University–New Brunswick have bred mice that exhibit some of the same behaviors and brain abnormalities seen in humans with the disorder.

6 May 2024

Study identifies APOE4 homozygotes as high-risk group for Alzheimer's disease

Researchers from the Research Area on Neurological Diseases, Neuroscience, and Mental Health at the Sant Pau Research Institute, led by Dr. Juan Fortea, Director of the Memory Unit of the Neurology Service at the same hospital, have found that over 95% of individuals over 65 years old who have two copies of the APOE4 gene -APOE4 homozygotes- show biological characteristics of Alzheimer's pathology in the brain or biomarkers of this disease in cerebrospinal fluid and PET scans.

6 May 2024

Syndrome News and Research

Obesity, metabolic syndrome impact breast cancer subtypes and mortality

Researchers discover how gut microbes influence social behavior in mice

Study shows clear benefit from COVID-19 vaccination for heart failure patients

Bats in China found to carry novel herpesviruses, hinting at cross-species transmission dangers

Enhanced weight loss outcomes with GLP-1 analogues and bupropion/naltrexone combination

Study sheds light on challenges faced by caregivers of children with genetic conditions

Can vitamin D3 supplementation reduce COVID-19 severity?

A previously unknown post-COVID syndrome found

AML patients at the extremes of older age derive benefit from VEN-HMA regimen

Higher consumption of ultra-processed foods linked to elevated mortality risk

Novel bispecific antibodies show promise against evolving SARS-CoV-2 variants

Heightened risk of adverse neonatal outcomes from prenatal exposure to both cannabis and nicotine

Underdiagnosed and common: Study highlights neuropathy's hidden toll

Brain-computer interface translates ALS patient's brain activity into spoken words

New tool more accurately predicts an individual's 10-year risk of cardiovascular diseases

Molecular pathology of Schaaf-Yang syndrome: Insights into MAGEL2 gene mutations and truncated proteins

APOE4 gene linked to early onset Alzheimer's, target for therapeutic intervention

New Quartet nanocage vaccine shows promise against coronavirus variants

Rutgers scientists create CRISPR-edited mice to study the neurobiology of Tourette disorder

Study identifies APOE4 homozygotes as high-risk group for Alzheimer's disease

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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