Gene News and Research

Latest Gene News and Research

New biomarker predicts immunotherapy response in gastrointestinal cancers

Despite significant progress in treating gastrointestinal (GI) cancers through surgical resection, chemotherapy, radiotherapy, and targeted therapy, the objective response rate (ORR) for immune checkpoint inhibitor (ICI) therapy remains low.

30 Apr 2024

Groundbreaking study reveals over 100 new genomic regions linked to blood pressure

National Institutes of Health researchers and collaborators have discovered over 100 new regions of the human genome, also known as genomic loci, that appear to influence a person's blood pressure.

30 Apr 2024

ZIP7: A novel target for treating degenerative diseases associated with misfolded proteins

Proteins are the workhorses of life. Organisms use them as building blocks, receptors, processors, couriers and catalysts.

30 Apr 2024

Deciphering the role of Th2-multipotent progenitor cells in chronic allergic inflammation

Currently, most therapies for allergic diseases require lifelong treatment. Allergic reactions, characterized by ongoing (type 2) inflammation in response to chronic antigen exposure, underlie many chronic diseases in humans, including asthma, atopic dermatitis, ulcerative colitis and more.

30 Apr 2024

Genetic propensity to higher arachidonic acid levels linked to lower bipolar disorder risk

A genetic propensity to higher circulating levels of lipids containing arachidonic acid, an omega-6 polyunsaturated fatty acid found in eggs, poultry, and seafood, has been found to be linked with a lower risk for bipolar disorder, according to a new study in Biological Psychiatry, published by Elsevier.

30 Apr 2024

AI-MARRVEL: A leap forward in diagnosing genetic diseases with over 98% precision

The knowledge-driven MARRVEL AI-based model (AIM) to identify Mendelian illnesses.

30 Apr 2024

New Kaposi sarcoma mouse model could be key to drug development

Researchers at UNC Lineberger Comprehensive Cancer Center, after decades of research efforts, have developed a mouse model of Kaposi sarcoma that could be key to the development of new drugs to treat the disease.

29 Apr 2024

Study reveals genetic divergence and drug resistance mechanisms in two critical superbugs

Infectious diseases caused by pathogenic strains of bacteria are a global cause of morbidity and mortality. Hospital-acquired infections caused by Klebsiella pneumonia and Pseudomonas aeruginosa were found vulnerable during the COVID-19 pandemic.

29 Apr 2024

Genetic associations of key genes in breast cancer pathogenesis

Breast cancer remains a significant global health concern, warranting further exploration into its genetic basis and potential therapeutic targets.

29 Apr 2024

Unlocking the mechanisms of pluripotent cell's fate determination

As embryos, all complex organisms are partially made up of pluripotent stem cells, a term for cells that have the capacity to differentiate into any kind of cell: nerve cells, muscle cells, blood cells, skin cells, and the like.

29 Apr 2024

Renewed classification of primary iron overload syndromes based on Hep25/FP system

The clinical introduction of hepcidin25 (Hep25) has led to a more detailed understanding of its relationship with ferroportin (FP) and divalent metal transporter1 in primary iron overload syndromes (PIOSs).

29 Apr 2024

Study reveals brown fat's built-in mechanism and potential obesity treatment

Brown fat, also known as brown adipose tissue (BAT), is a type of fat in our bodies that's different from the white fat around our belly and thighs that we are more familiar with.

29 Apr 2024

SCA4 genetic breakthrough: Unveiling the cause of a devastating neurological disease

Some families call it a trial of faith. Others just call it a curse. The progressive neurological disease known as spinocerebellar ataxia 4 (SCA4) is a rare condition, but its effects on patients and their families can be severe.

29 Apr 2024

UK study confirms healthy habits can extend lifespan, even with genetic predispositions

The associations between lifestyle, genetic factors, and human longevity.

29 Apr 2024

New blood test shows promise in early detection of ovarian cancer

A study reveals that glycoproteins in blood could be key biomarkers for early detection and staging of epithelial ovarian cancer, potentially allowing diagnosis through a simple blood test.

28 Apr 2024

New study reveals potential cellular mechanism behind cognitive decline in Alzheimer's

Researchers have developed a robust method for identifying rare brain neurons that re-enter the cell cycle, offering insights into their role in cognitive disorders such as Alzheimer's disease.

28 Apr 2024

Leveraging CRISPR/Cas technology to address antimicrobial resistance

In the second new research review on this subject, Assistant Prof. Ibrahim Bitar, Department of Microbiology, Faculty of Medicine and University Hospital in Plzen, Charles University in Prague, Plzen, Czech Republic, will give an overview of the molecular biology of CRISPR technology in explaining how it can used to tackle antimicrobial resistance.

26 Apr 2024

Study reveals how genetic changes in SCN2A gene impact autism and epilepsy

A genetic change or variant in a gene called SCN2A is a known cause of infantile seizures, autism spectrum disorder and intellectual disability, as well as a wide range of other moderate-to-profound impairments in mobility, communication, eating and vision.

26 Apr 2024

Ketone supplement boosts efficacy of prostate cancer immunotherapy

Adding a pre-ketone supplement -; a component of a high-fat, low-carb ketogenic diet -; to a type of cancer therapy in a laboratory setting was highly effective for treating prostate cancer, researchers from the University of Notre Dame found.

26 Apr 2024

Largest study of BRCA1 and BRCA2 carriers refines cancer risk estimates in Asian population

A team of clinician-scientists and scientists from the University of Nottingham (Malaysia campus), National Cancer Centre Singapore (NCCS), Cancer Research Malaysia, Nanyang Technological University, Singapore (NTU Singapore), University of Malaya, University of Cambridge, A*STAR's Genome Institute of Singapore (GIS) and other institutions, have conducted the largest study done to date of BRCA1 and BRCA2 (BReast CAncer Gene 1 and 2) carriers in an Asian population and refined breast and ovarian cancer risk estimates for this population.

26 Apr 2024

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Gene News and Research

Latest Gene News and Research

New biomarker predicts immunotherapy response in gastrointestinal cancers

Groundbreaking study reveals over 100 new genomic regions linked to blood pressure

ZIP7: A novel target for treating degenerative diseases associated with misfolded proteins

Deciphering the role of Th2-multipotent progenitor cells in chronic allergic inflammation

Genetic propensity to higher arachidonic acid levels linked to lower bipolar disorder risk

AI-MARRVEL: A leap forward in diagnosing genetic diseases with over 98% precision

New Kaposi sarcoma mouse model could be key to drug development

Study reveals genetic divergence and drug resistance mechanisms in two critical superbugs

Genetic associations of key genes in breast cancer pathogenesis

Unlocking the mechanisms of pluripotent cell's fate determination

Renewed classification of primary iron overload syndromes based on Hep25/FP system

Study reveals brown fat's built-in mechanism and potential obesity treatment

SCA4 genetic breakthrough: Unveiling the cause of a devastating neurological disease

UK study confirms healthy habits can extend lifespan, even with genetic predispositions

New blood test shows promise in early detection of ovarian cancer

New study reveals potential cellular mechanism behind cognitive decline in Alzheimer's

Leveraging CRISPR/Cas technology to address antimicrobial resistance

Study reveals how genetic changes in SCN2A gene impact autism and epilepsy

Ketone supplement boosts efficacy of prostate cancer immunotherapy

Largest study of BRCA1 and BRCA2 carriers refines cancer risk estimates in Asian population

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer