Gene Expression News and Research

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Gene Expression is the process by which a gene gets turned on in a cell to make RNA and proteins. Gene expression may be measured by looking at the RNA, or the protein made from the RNA, or what the protein does in a cell.

Single infusion of engineered T-cells achieves lasting asthma remission in mice

Researchers demostrate that durable asthma remission can be achieved with engineered and long-lived CAR T-cell treatment in mice.

31 May 2024

Researchers uncover two classes of genetic causes for pediatric chordoma

Little is known about the genetics and biology of chordoma, a rare and aggressive bone tumor. Chordomas occur in approximately one in a million people in the U.S. a year and only five percent of these are in children.

30 May 2024

Mast cells and PGE2: Key players in controlling asthma inflammation

Previous research indicates that mast cells, a type of immune cell found in the tissues throughout the body, cause inflammation during an asthma attack, inducing symptoms such as trouble breathing and narrowing of the airways.

30 May 2024

hnRNPM's protective role in protein synthesis precision uncovered

Researchers at Baylor College of Medicine and collaborating institutions have discovered that a protein called hnRNPM helps protect the integrity of the process cells use to make proteins.

30 May 2024

Exercise-induced exerkines: Secret weapon in disease prevention and therapy

A recent review in Signal Transduction and Targeted Therapy highlights the role of exercise-induced molecules, exerkines, in disease prevention and treatment, emphasizing their molecular mechanisms and therapeutic potential.

29 May 2024

Heart-healthy habits keep you biologically young, study shows

A new study in the Journal of the American Heart Association reveals that heart-healthy lifestyle factors are linked to younger biological age and lower cardiovascular disease risk through DNA methylation.

29 May 2024

Study reveals new link between high temperature exposure and sphingolipid metabolism in obesity

In contemporary society, obesity has emerged as a worldwide chronic metabolic disorder, imposing substantial burdens on both individual health and healthcare systems.

29 May 2024

Heart healthy behaviors may slow biological aging, research shows

The benefit of better heart health may be associated with the positive impact of heart healthy lifestyle factors on biological aging (the age of the body and its cells), according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

29 May 2024

Study finds Plexin-B1 could be key to Alzheimer’s treatment, enhancing glial cell response

Researchers discovered that Plexin-B1 plays a crucial role in regulating peri-plaque glial nets in Alzheimer’s disease, potentially opening new avenues for treatment by targeting this protein.

29 May 2024

MUSC researchers unravel the mystery of cancer recurrence

MUSC Hollings Cancer Center researchers have unlocked a discovery that could help to explain why cancer can recur in patients who have undergone chemotherapy or radiotherapy.

28 May 2024

Understanding the link between EBV-infected B cells and multiple sclerosis

The Wistar Institute's Paul M. Lieberman, Ph.D., and lab team led by senior staff scientist and first author, Samantha Soldan, Ph.D., have demonstrated how B cells infected with the Epstein-Barr virus (EBV) can contribute to a pathogenic, inflammatory phenotype that contributes to multiple sclerosis (MS); the group has also shown how these problematic B cells can be selectively targeted in a way that reduces the damaging autoimmune response of multiple sclerosis.

28 May 2024

Heart failure triggers multimorbidity by altering stem cells, study reveals

Researchers identified that heart failure (HF) promotes multimorbidity by altering hematopoietic stem cells (HSCs) to produce pro-inflammatory macrophages, increasing vulnerability in multiple organs. The study highlights the role of suppressed TGF-β signaling in these alterations, contributing to chronic inflammation and subsequent health issues.

28 May 2024

Study sheds new light on the intricate molecular mechanisms underlying schizophrenia

Schizophrenia is a complex disease with variable presentations, and the diverse nature of this mental health disorder has made understanding the mechanisms that cause the disease, and subsequently developing effective treatments, especially challenging.

24 May 2024

Comprehensive study provides new understandings of genomic influences on neuropsychiatric disease

A new analysis has revealed detailed information about genetic variation in brain cells that could open new avenues for the targeted treatment of diseases such as schizophrenia and Alzheimer's disease.

23 May 2024

Mouse study finds PFAS exposure in fathers disrupts offspring's gene expression

Research reveals that preconception exposure to PFAS in male mice alters sperm methylation and affects gene expression in the liver and fat of their offspring.

23 May 2024

Gene cluster expression analysis for personalized lung cancer therapy

About 30% of lung cancer patients are accessible to targeted therapy or immunotherapy based on the current criteria.

23 May 2024

New chemical modification improves effectiveness and safety of ASO therapy for CNS diseases

Diseases that affect the brain and spinal cord can be particularly devastating, and finding new and more effective ways to treat these conditions is an important goal for researchers and clinicians alike.

23 May 2024

Researchers discover advances in predicting kidney failure in type 1 diabetes patients

In a paper published today in Science Translational Medicine, researchers from City of Hope, one of the largest cancer research and treatment organizations in the United States and a leading research center for diabetes and other life-threatening illnesses, report that they have discovered advances in predicting kidney failure in type 1 diabetes (T1D) patients.

22 May 2024

Improved animal model captures full picture of periodontal disease progression

Periodontal disease, represented by periodontitis, is the leading cause of tooth loss and affects close to one in five adults worldwide.

22 May 2024

Groundbreaking study advances human in vitro gametogenesis for infertility treatment

Infertility affects approximately 1 in 6 people in their lifetime worldwide according to the World Health Organization (WHO).

21 May 2024

Gene Expression News and Research

Further Reading

Single infusion of engineered T-cells achieves lasting asthma remission in mice

Researchers uncover two classes of genetic causes for pediatric chordoma

Mast cells and PGE2: Key players in controlling asthma inflammation

hnRNPM's protective role in protein synthesis precision uncovered

Exercise-induced exerkines: Secret weapon in disease prevention and therapy

Heart-healthy habits keep you biologically young, study shows

Study reveals new link between high temperature exposure and sphingolipid metabolism in obesity

Heart healthy behaviors may slow biological aging, research shows

Study finds Plexin-B1 could be key to Alzheimer’s treatment, enhancing glial cell response

MUSC researchers unravel the mystery of cancer recurrence

Understanding the link between EBV-infected B cells and multiple sclerosis

Heart failure triggers multimorbidity by altering stem cells, study reveals

Study sheds new light on the intricate molecular mechanisms underlying schizophrenia

Comprehensive study provides new understandings of genomic influences on neuropsychiatric disease

Mouse study finds PFAS exposure in fathers disrupts offspring's gene expression

Gene cluster expression analysis for personalized lung cancer therapy

New chemical modification improves effectiveness and safety of ASO therapy for CNS diseases

Researchers discover advances in predicting kidney failure in type 1 diabetes patients

Improved animal model captures full picture of periodontal disease progression

Groundbreaking study advances human in vitro gametogenesis for infertility treatment

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