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Single infusion of engineered T-cells achieves lasting asthma remission in mice

Researchers demostrate that durable asthma remission can be achieved with engineered and long-lived CAR T-cell treatment in mice.

31 May 2024

Notre Dame study identifies high-risk population for CAUTIs due to fibrinolytic deficiencies

Urinary catheters are required for nearly every surgical procedure. However, a major challenge for the health care industry is predicting who may develop catheter-associated urinary tract infections (CAUTIs) and when these infections may lead to death.

30 May 2024

Canagliflozin: A breakthrough in senolytic treatment for aging-related diseases

Aging-related physiological decline and the accumulation of senescent or aging cells in bodily tissues can trigger a number of diseases.

30 May 2024

Mast cells and PGE2: Key players in controlling asthma inflammation

Previous research indicates that mast cells, a type of immune cell found in the tissues throughout the body, cause inflammation during an asthma attack, inducing symptoms such as trouble breathing and narrowing of the airways.

30 May 2024

Existing drug alleviates symptoms of a rare genetic syndrome

A drug approved to treat certain autoimmune diseases and cancers successfully alleviated symptoms of a rare genetic syndrome called autoimmune polyendocrine syndrome type 1 (APS-1).

30 May 2024

Statins may block an inflammation pathway involved in the development of cancer

A new study led by investigators from Mass General Cancer Center, a founding member of the Mass General Brigham healthcare system, reveals that statins-;commonly used cholesterol-lowering drugs-;may block a particular pathway involved in the development of cancer that results from chronic inflammation.

30 May 2024

Surface-enhanced raman spectroscopy for precise diagnosis of infections

Every year, medical diagnostics are getting better and better thanks to the tremendous development of new methods that enable the precise detection of the many different molecules present in biological fluids during an infection.

29 May 2024

Proline-based nano cages offer targeted drug delivery, limit side effects of chemotherapy

A new method of drug delivery using proline, an amino acid found in chicken feathers and skin tissue, could be used to limit the side effects of chemotherapy and repair important enzymes, new research suggests.

29 May 2024

Study offers insight into early developmental risk factors for ADHD

Several early developmental factors are associated with an increased risk of ADHD during childhood and adolescence.

29 May 2024

Study finds Plexin-B1 could be key to Alzheimer’s treatment, enhancing glial cell response

Researchers discovered that Plexin-B1 plays a crucial role in regulating peri-plaque glial nets in Alzheimer’s disease, potentially opening new avenues for treatment by targeting this protein.

29 May 2024

Study highlights a dietary strategy for health improvement and weight management

A new study by researchers from Arizona State University and their colleagues highlights a dietary strategy for significant health improvement and weight management.

28 May 2024

Tattoos linked to higher risk of malignant lymphoma, study finds

A recent study in eClinicalMedicine links tattoo ink exposure to a 21% higher risk of malignant lymphoma, particularly B-cell subtypes. Tattoo ink and laser removal may play significant roles in lymphoma development.

28 May 2024

Semaglutide shows significant kidney benefits in non-diabetic obese patients with heart disease

A recent study in Nature Medicine shows semaglutide reduces kidney risks in non-diabetic obese patients with cardiovascular disease by 22%. The SELECT trial results highlight semaglutide's benefits for kidney function and overall cardiovascular health.

28 May 2024

Silibinin: An old molecule with new promise in cancer treatment

A new review paper was published in Oncotarget's Volume 15 on May 23, 2024, entitled, "The importance of integrated therapies on cancer: Silibinin, an old and new molecule."

28 May 2024

Research reveals loneliness as a complex interplay of social impairments, oxytocin, and illness

A recent review in the journal Neuroscience & Biobehavioral Reviews presents a multidimensional model of loneliness, exploring its impact on social interactions, the oxytocin system, and illness. The study emphasizes the need for multidisciplinary collaboration to understand and address loneliness effectively.

28 May 2024

New paper reveals the broad potential of TNIK as a therapeutic target for some aging-related diseases

A new paper in Trends in Pharmacological Sciences from researchers at generative artificial intelligence (AI)- and robotics-powered clinical stage drug discovery company Insilico Medicine ("Insilico") and ETH Zurich reveals the broad potential of TNIK as a therapeutic target for some of the most pervasive aging-related diseases, including fibrosis, cancer, obesity, and Alzheimer's.

28 May 2024

Simple vaginal swab could help detect early-stage gynecological cancers

A simple vaginal swab could reveal the presence of early-stage gynecological cancers, according to a new, wide-ranging study published in De Gruyter's Open Life Sciences.

28 May 2024

Understanding the link between EBV-infected B cells and multiple sclerosis

The Wistar Institute's Paul M. Lieberman, Ph.D., and lab team led by senior staff scientist and first author, Samantha Soldan, Ph.D., have demonstrated how B cells infected with the Epstein-Barr virus (EBV) can contribute to a pathogenic, inflammatory phenotype that contributes to multiple sclerosis (MS); the group has also shown how these problematic B cells can be selectively targeted in a way that reduces the damaging autoimmune response of multiple sclerosis.

28 May 2024

New point-of-care test revolutionizes toxoplasmosis screening

An inexpensive, accurate test that detects infections with the parasite Toxoplasma gondii can provide results within 30 minutes from a finger-prick in a doctor's office or within an hour from a small blood sample tested in a local medical laboratory.

28 May 2024

Study reveals pivotal role of the circadian clock in enhancing checkpoint inhibitor cancer therapy

A multidisciplinary research team at the University of California, Irvine has revealed that the circadian clock – the biological pacemaker that governs daily rhythms in physiological processes, including immune functions – can be leveraged to enhance the efficacy of checkpoint inhibitor cancer therapy.

28 May 2024

Inflammation News and Research

Single infusion of engineered T-cells achieves lasting asthma remission in mice

Notre Dame study identifies high-risk population for CAUTIs due to fibrinolytic deficiencies

Canagliflozin: A breakthrough in senolytic treatment for aging-related diseases

Mast cells and PGE2: Key players in controlling asthma inflammation

Existing drug alleviates symptoms of a rare genetic syndrome

Statins may block an inflammation pathway involved in the development of cancer

Surface-enhanced raman spectroscopy for precise diagnosis of infections

Proline-based nano cages offer targeted drug delivery, limit side effects of chemotherapy

Study offers insight into early developmental risk factors for ADHD

Study finds Plexin-B1 could be key to Alzheimer’s treatment, enhancing glial cell response

Study highlights a dietary strategy for health improvement and weight management

Tattoos linked to higher risk of malignant lymphoma, study finds

Semaglutide shows significant kidney benefits in non-diabetic obese patients with heart disease

Silibinin: An old molecule with new promise in cancer treatment

Research reveals loneliness as a complex interplay of social impairments, oxytocin, and illness

New paper reveals the broad potential of TNIK as a therapeutic target for some aging-related diseases

Simple vaginal swab could help detect early-stage gynecological cancers

Understanding the link between EBV-infected B cells and multiple sclerosis

New point-of-care test revolutionizes toxoplasmosis screening

Study reveals pivotal role of the circadian clock in enhancing checkpoint inhibitor cancer therapy

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