Telomere

A telomere is a region of repetitive DNA at the end of a chromosome, which protects the end of the chromosome from deterioration.

What are Telomeres?

Telomeres are crucial parts of the chromosome that act to protect them and ensure DNA replication is performed effectively.

Systemic Telomere Length and Aging

Latest Telomere News and Research

Study reveals new insight into how human telomeres function at the molecular level

The length of telomeres that protect the ends of our chromosomes should be tightly regulated. Those that are too long predispose to cancer, and those that are too short lose their protective ability, resulting in telomere disorders with serious health consequences.

4 Jun 2024

Young bone marrow transplants show promise in reversing Alzheimer's symptoms in mice

Researchers found that young bone marrow transplants rejuvenate aging immune cells, reducing Alzheimer's symptoms in mice models, suggesting a potential therapeutic approach for the disease.

4 Jun 2024

Family's rare telomere mutation reveals new insights into telomere flexibility and disease

Researchers discovered a rare telomere mutation (TTAGGT) in a family, revealing that human telomeres can tolerate non-canonical sequences, impacting telomere maintenance and disease.

4 Jun 2024

Life's Essential 8: key to reducing heart disease and mortality through epigenetics

Whether DNA methylation-based epigenetic age biomarkers mediate the associations between LE8 score and risks of CVD, CVD-specific mortality, and all-cause mortality.

31 May 2024

Enzyme implicated in telomere repair offers new avenues for cancer therapy

A new study led by University of Pittsburgh and UPMC Hillman Cancer Center researchers shows that an enzyme called PARP1 is involved in repair of telomeres, the lengths of DNA that protect the tips of chromosomes, and that impairing this process can lead to telomere shortening and genomic instability that can cause cancer.

7 May 2024

Study links early-life tobacco exposure to accelerated aging, urging preventive action

A recent study in Science Advances found that early-life tobacco exposure, including in-utero and early smoking initiation, accelerates biological aging, emphasizing the importance of reducing exposure to improve health outcomes.

6 May 2024

Does reproduction influence epigenetic aging in younger women?

The association between reproduction and biological aging based on epigenetic clocks.

25 Apr 2024

Protecting telomeres: ILF3 and the regulation of R-loop dynamics

Dysregulated R-loops can cause stalled replication forks and telomere instability. However, how R-loops are recognized and regulated, is still not well understood, particularly at telomeres.

22 Apr 2024

Penn State study examines how a person's telomeres are affected by caloric restriction

Penn State researchers may have uncovered another layer of complexity in the mystery of how diet impacts aging.

17 Apr 2024

Nanopore sequencing unveils novel telomere length patterns

We depend on our cells being able to divide and multiply, whether it's to replace sunburnt skin or replenish our blood supply and recover from injury.

12 Apr 2024

Regular late-life exercise has a beneficial impact on DNA damage and telomere dysfunction

Regular aerobic exercise later in life prevents genomic instability characterized by DNA damage and telomere dysfunction, according to a study from the Department of Internal Medicine at the University of Utah.

7 Apr 2024

Vitamin D shows promise in targeting aging's biological mechanisms, study finds

What is currently known about the potential effect of vitamin D (VitD) on modulating some hallmarks of aging.

26 Mar 2024

Link between gut microbiome and premature aging unveiled in chronic HIV patients

The Wistar Institute's associate professor Mohamed Abdel-Mohsen, Ph.D., has demonstrated, with his lab and collaborators, a connection between viral damage to the gut and premature biological aging.

22 Feb 2024

GV1001 exerts anti-aging effects in triple transgenic Alzheimer's mice

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 3, entitled, "GV1001 reduces neurodegeneration and prolongs lifespan in 3xTg-AD mouse model through anti-aging effects."

15 Feb 2024

Magnesium's pivotal role in slowing aging's impact

Review highlights magnesium's critical role in mitigating aging hallmarks, including telomere attrition, genomic instability, epigenetic alterations, loss of proteostasis, mitochondrial dysfunction, cellular senescence, and stem cell exhaustion, suggesting that maintaining adequate magnesium levels could support healthy aging.

13 Feb 2024

Telomere

Overview

Telomere Shortening

Systemic Telomere Length and Aging

Telomeres and Cancer

Feature Articles

Telomere Function

Telomere Lengthening

Telomere Measurement

Latest Telomere News and Research

Study reveals new insight into how human telomeres function at the molecular level

Young bone marrow transplants show promise in reversing Alzheimer's symptoms in mice

Family's rare telomere mutation reveals new insights into telomere flexibility and disease

Life's Essential 8: key to reducing heart disease and mortality through epigenetics

Enzyme implicated in telomere repair offers new avenues for cancer therapy

Study links early-life tobacco exposure to accelerated aging, urging preventive action

Does reproduction influence epigenetic aging in younger women?

Protecting telomeres: ILF3 and the regulation of R-loop dynamics

Penn State study examines how a person's telomeres are affected by caloric restriction

Nanopore sequencing unveils novel telomere length patterns

Regular late-life exercise has a beneficial impact on DNA damage and telomere dysfunction

Vitamin D shows promise in targeting aging's biological mechanisms, study finds

Link between gut microbiome and premature aging unveiled in chronic HIV patients

GV1001 exerts anti-aging effects in triple transgenic Alzheimer's mice

Magnesium's pivotal role in slowing aging's impact

Discovery on housekeeping genetic elements reveals a novel avenue in cancer therapy

Air pollution may affect male reproduction via oxidative stress, says study

Study uncovers vast genomic diversity in Aboriginal Australian communities

Vegan diet improves cardiovascular health in 8 weeks, twin study finds

Reversing biological age could increase longevity and lower dementia and stroke risk

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?