Drug Trial News

RSS

Scalable synthetic biology revolutionizes targeted therapy with logic-gate proteins

Targeted drug delivery is a powerful and promising area of medicine. Therapies that pinpoint the exact areas of the body where they're needed - and nowhere they're not - can reduce the medicine dosage and avoid potentially harmful "off target" effects elsewhere in the body.

10 Oct 2025

New dual-target vaccine shows promise against typhoid and Salmonella

Researchers at the University of Maryland School of Medicine's Center for Vaccine Development and Global Health (CVD) have completed a successful Phase 1 clinical trial of a novel vaccine designed to protect against both typhoid fever and invasive non-typhoidal Salmonella--two major causes of illness and death among children in sub-Saharan Africa.

8 Oct 2025

New drug combination could delay the progression of advanced prostate cancer

A new drug combination could significantly delay the progression of a life-threatening form of prostate cancer in men with specific genetic mutations, finds a major international trial led by UCL researchers.

7 Oct 2025

New ASPIRE trial tests chemotherapy combination for advanced prostate cancer

The Alliance for Clinical Trials in Oncology has launched the ASPIRE trial-a large-scale, Phase III clinical study investigating whether adding chemotherapy to current standard treatments can extend survival for men living with advanced prostate cancer.

6 Oct 2025

FDA grants approval to begin Phase I clinical trials of heart tissue regeneration drug AD-NP1

The body's tissues can get injured in many ways, but while some injuries heal perfectly, others don't heal at all. A cut in the skin, for example, usually heals all on its own, while internal organs, such as the heart after a heart attack or the kidney after an acute injury, remain damaged, leading to diminished function.

6 Oct 2025

Antihypertensive and lipid-lowering drugs show efficacy against steatotic liver disease

Metabolic dysfunction-associated steatotic liver disease is the most common liver disease in the world, affecting about one third of the adult population. This disorder is characterized by the accumulation of fat in liver cells, which has severe liver consequences and is also associated with a high mortality rate from cardiovascular disease.

6 Oct 2025

World's first vaccine trial against elephant endotheliotropic herpesvirus proves safe and effective

The world's first vaccine trial against elephant endotheliotropic herpesvirus (EEHV) – a leading cause of death in young Asian elephants – is safe and triggers a strong virus-fighting immune response, according to an international team led by the University of Surrey, in collaboration with Chester Zoo and the Animal and Plant Health Agency.

3 Oct 2025

New study shows why HIV health recovery fails despite antiretroviral therapy

What if the presence of a well-known but misunderstood viral protein explains why some people living with HIV (PLWH) never recover their health, even with antiretroviral treatment?

3 Oct 2025

Early trial finds promise for avelumab and radiation in treating leptomeningeal disease

Researchers at Moffitt Cancer Center have reported encouraging results from a phase 1B clinical trial showing that the immunotherapy drug avelumab, when combined with whole brain radiotherapy, may provide a safe and effective treatment option for patients with leptomeningeal disease, one of the most aggressive and difficult-to-treat complications of advanced cancer.

30 Sep 2025

Sotatercept shows strong benefits for newly diagnosed pulmonary hypertension patients

Prescribing the biologic drug sotatercept alongside standard treatment for the most severe form of pulmonary hypertension significantly reduces the likelihood of worsening disease when added within the first year after diagnosis, according to a study published in the New England Journal of Medicine.

30 Sep 2025

2-in-1 budesonide-formoterol inhaler reduces children's asthma attacks by 45%

Findings from a trial comparing the real-world effectiveness of asthma inhalers could reshape how children with asthma are treated.

29 Sep 2025

Clinical trial disproves claims that antioxidant supplement boosts male fertility

A large Dutch randomized clinical trial (SUMMER) found that a widely marketed antioxidant supplement (Impryl) did not improve ongoing pregnancy rates in men seeking fertility care. Instead, pregnancy success was significantly lower in the critical 4–6 month treatment window, raising safety concerns.

28 Sep 2025

Ocrelizumab provides superior control of multiple sclerosis relapses compared to other therapies

New research presented at the 41st Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS 2025) demonstrates that ocrelizumab provides superior control of multiple sclerosis (MS) relapses compared with fingolimod, natalizumab, and alemtuzumab.

23 Sep 2025

Orforglipron pill improves heart and metabolic risk factors in trial

Patients taking an experimental oral GLP-1 drug lost significant weight and improved their heart and metabolic risk factors in a large, international, phase 3 clinical trial led by investigators at Weill Cornell Medicine, McMaster University, York University and other institutions.

22 Sep 2025

New dialysis filter shows promise for improving survival and health in kidney failure patients

Researchers at London Health Sciences Centre Research Institute (LHSCRI) and Western University's Schulich School of Medicine & Dentistry have launched a clinical trial that is evaluating a new type of dialysis filter called Elisio HX that may significantly improve outcomes for people living with kidney failure across Canada.

22 Sep 2025

Oral drug baricitinib shows promise in slowing early type 1 diabetes progression

In 2023, the groundbreaking Australian BANDIT (Baricitinib in New Onset Type 1 Diabetes) trial [1] reported that a daily pill of baricitinib, commonly prescribed for rheumatoid arthritis and alopecia, could safely preserve the body's own insulin production and slow the progression of type 1 diabetes (T1D) in people recently diagnosed with the condition.

19 Sep 2025

Verapamil shows potential for preserving beta-cell function in type 1 diabetes

New research (the Ver-A-T1D trial) presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) (Vienna, 15-19 September) shows that slow-release (SR) verapamil (360mg daily) could have a potential effect on beta-cell function in adults with newly diagnosed type 1 diabetes.

18 Sep 2025

New trial demonstrates efficacy of tirzepatide in children and adolescents with type 2 diabetes

New research shows that that the diabetes/obesity medication tirzepatide can cause clinically meaningful improvements in blood sugar control and weight loss in children and adolescents with type 2 diabetes aged 10-17 years whose diabetes and weight are inadequately controlled with an existing treatment regimen of metformin, insulin, or both.

18 Sep 2025

Daily orforglipron GLP-1 pill achieves over 11% weight loss in global obesity trial

In a phase 3 trial, once-daily oral orforglipron induced significant, dose-dependent weight loss over 72 weeks in adults with obesity but no diabetes. It also improved multiple cardiometabolic markers with a safety profile similar to other GLP-1 receptor agonists.

18 Sep 2025

Clinical trial reveals encouraging results for apitegromab in spinal muscular atrophy

A new clinical trial has revealed encouraging results for a muscle-targeting therapy aimed at improving motor function in children and adolescents with spinal muscular atrophy, according to a study published in The Lancet Neurology.

18 Sep 2025

1
2
3
4
...
1157
Next

Drug Trial News

Scalable synthetic biology revolutionizes targeted therapy with logic-gate proteins

New dual-target vaccine shows promise against typhoid and Salmonella

New drug combination could delay the progression of advanced prostate cancer

New ASPIRE trial tests chemotherapy combination for advanced prostate cancer

FDA grants approval to begin Phase I clinical trials of heart tissue regeneration drug AD-NP1

Antihypertensive and lipid-lowering drugs show efficacy against steatotic liver disease

World's first vaccine trial against elephant endotheliotropic herpesvirus proves safe and effective

New study shows why HIV health recovery fails despite antiretroviral therapy

Early trial finds promise for avelumab and radiation in treating leptomeningeal disease

Sotatercept shows strong benefits for newly diagnosed pulmonary hypertension patients

2-in-1 budesonide-formoterol inhaler reduces children's asthma attacks by 45%

Clinical trial disproves claims that antioxidant supplement boosts male fertility

Ocrelizumab provides superior control of multiple sclerosis relapses compared to other therapies

Orforglipron pill improves heart and metabolic risk factors in trial

New dialysis filter shows promise for improving survival and health in kidney failure patients

Oral drug baricitinib shows promise in slowing early type 1 diabetes progression

Verapamil shows potential for preserving beta-cell function in type 1 diabetes

New trial demonstrates efficacy of tirzepatide in children and adolescents with type 2 diabetes

Daily orforglipron GLP-1 pill achieves over 11% weight loss in global obesity trial

Clinical trial reveals encouraging results for apitegromab in spinal muscular atrophy

Reimagining light scattering for biotherapeutics

Empowering genomics research with cloud-based innovation

Quality, Patient Safety and Innovation Manager at Elsevier

Latest News