Non Small Cell Lung Cancer News and Research

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Non-Small Cell Lung Cancers are a group of lung cancers that are named for the kinds of cells found in the cancer and how the cells look under a microscope. The three main types of non-small cell lung cancer are squamous cell carcinoma, large cell carcinoma, and adenocarcinoma. Non-small cell lung cancer is the most common kind of lung cancer.

Genmab starts HuMax-EGFr combination study

Genmab A/S has announced it has initiated a Phase II study of HuMax-EGFr (zalutumumab) in combination with chemo-radiation to treat non small cell lung cancer (NSCLC).

15 Apr 2007

Massive gene screening points way to more effective chemotherapy

Using a technology that can quickly screen all 20,000-plus human genes for biological activity, scientists have isolated 87 genes that seem to affect how sensitive human cancer cells are to certain chemotherapy drugs.

12 Apr 2007

Thoracoscopic lobectomy can improve chemotherapy for lung cancer outcomes

Patients who undergo a minimally invasive lung cancer surgery called thoracoscopic lobectomy may derive more benefit from the chemotherapy that follows, according to Duke University Medical Center researchers.

10 Apr 2007

Pharmacyclics undergoes 'file over protest' for Xcytrin NDA

Pharmacyclics, Inc. has announced its request to the U.S. Food and Drug Administration (FDA) that its New Drug Application (NDA) for Xcytrin (motexafin gadolinium) Injection be filed over protest.

5 Apr 2007

Lack of Olig1 protein in lung tumors may increase risk of death

A study of human lung tumors indicates that lung cancer patients who lack a particular protein may do more poorly than those with normal levels of that same protein.

2 Apr 2007

RF ablation used to treat early-stage, inoperable cancer

Lung cancer patients who are not candidates for surgery now have another safe and effective treatment option: radiofrequency (RF) ablation, according to a new study published in the April issue of the journal Radiology.

31 Mar 2007

Stimuvax investigational lung cancer vaccine phase III study starts

Merck KGaA today announced that the first patient has been enrolled in its global Phase III clinical study, START (Stimulating Targeted Antigenic Responses To NSCLC), assessing the efficacy and safety of Stimuvax (BLP25 liposome vaccine) as a potential treatment for patients with unresectable stage III non-small cell lung cancer (NSCLC).

26 Feb 2007

Simple diagnostic test detects genetic signs of lung cancer in sputum

DNA coughed up along with phlegm could point to lung cancer, say researchers at the University of Maryland School of Medicine who are developing an inexpensive and non-invasive gene probe to help diagnose early stage lung cancer in current and former smokers.

18 Jan 2007

Successful lung cancer surgery not enough to break nicotine dependence in many smokers

A new study has found that close to half of 154 smokers who had surgery to remove early stage lung cancer picked up a cigarette again within 12 months of their potentially curative operation, and more than one-third were smoking at the one year mark. Sixty percent of patients who started smoking again did so within two months of surgery.

12 Dec 2006

Nanoparticles for two-photon photodynamic therapy in living cells

Photodynamic therapy (PDT) uses a combination of ultraviolet or visible light and a light-sensitive chemical, or photosensitizer, to kill cancer cells using reactive oxygen.

6 Nov 2006

New drug gives hope to lung cancer victims

More people die from lung cancer than any other type of cancer and the prognosis for the disease is poor.

28 Sep 2006

Protein test on lung cancer cells predicts who will benefit from chemo

European researchers say a test can predict whether chemotherapy will help patients with lung cancer live longer after surgery.

7 Sep 2006

Modern radiation therapy ups lung cancer survival

Modern three-dimensional radiation therapy has been proven to be more successful at curing lung cancer than older two-dimensional radiation therapy for some patients with early stage lung cancer, according to a new study.

31 Aug 2006

St. John's wort and polymeric nanoparticles to treat ovarian tumors using light

By combining a compound produced by the plant St. John's wort with polymeric nanoparticles, researchers at the University of Geneva in Switzerland have developed a promising method for treating ovarian tumors using light.

21 Aug 2006

Gene test for cancers could mean more effective, tailored-made treatment

Scientists in the United States have developed a test which is able to predict which lung cancer tumours are most likely to recur.

14 Aug 2006

Nexavar approved in Europe for treatment of advanced kidney cancer

Bayer Pharmaceuticals Corporation and Onyx Pharmaceuticals, Inc have announced that the European Commission has granted marketing authorization to Nexavar (sorafenib) tablets for the treatment of patients with advanced renal cell carcinoma.

24 Jul 2006

Simple blood test detects lung cancer before it's too late

Researchers in the United States have developed a blood test that is able to correctly predict non-small-cell lung cancer in patients years before any CT scan (computed tomography) can trace it.

17 Jul 2006

New hope for ways to overcome drug resistance in lung cancer

Scientists have suggested it may be possible to reverse drug resistance in lung cancer patients, thereby improving the effectiveness of chemotherapy, according to research published in the EMBO Journal.

13 Jul 2006

Bortezomib extends lung cancer survival

Adding the new molecularly targeted agent bortezomib to a standard chemotherapy regimen of gemcitabine and carboplatin prolongs survival in patients with advanced non-small cell lung cancer, according to results from a phase II trial.

9 Jun 2006

Sunitinib malate shows promise against advanced form of lung cancer

Results of a multi-center clinical study of a drug currently approved for treatment of kidney cancer indicate that it may also be effective for people with recurrent and advanced lung cancer.

5 Jun 2006