Clinical Trial News and Research

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Women who have diets rich in oils containing alpha-linolenic appear to have a lower risk of dying from heart disease

Women who reported eating diets rich in oils containing alpha-linolenic acid (ALA) seemed to have a lower risk of dying from heart disease and sudden cardiac death than women whose diets are low in the plant-derived fatty acid, researchers reported at the American Heart Association’s Scientific Sessions 2004.

9 Nov 2004

New valve repair device that could replace major heart surgery

The Hospital of the University of Pennsylvania (HUP) is participating in a nationwide clinical trial of a new valve repair device that could replace major heart surgery in some patients.

8 Nov 2004

Major bone trial to test high dose corticosteroid steroid tablets

Researchers in Aberdeen are about to launch a major multi-centre clinical trial to test whether a new drug could prevent bone thinning in adults taking moderate to high dose corticosteroid "steroid" tablets, such as prednisolone.

8 Nov 2004

Link between immune protein and longer survival in melanoma patients

Immune responses to prevent or delay the spread of melanoma, a deadly form of skin cancer, are more likely to prolong survival in patients if their immune cells carry a special kind of marker on the surface, according to a team of researchers at the University of Virginia Health System.

5 Nov 2004

Trial of new type of drug that attacks amyloid

Neuroscientists at the Farber Institute for Neurosciences at Thomas Jefferson University in Philadelphia will begin a clinical trial testing a new type of drug that attacks amyloid, the protein substance that accumulates in the brains of Alzheimer’s disease patients.

4 Nov 2004

Psoriasis trial enters final stage

Solbec Pharmaceuticals Ltd today announced the successful completion of the first two stages of the Phase I clinical trial of its lead compound, CoramsineTM (SBP002), for the treatment of psoriasis.

4 Nov 2004

European approval for Taxotere (docetaxel) in prostate cancer

Aventis, part of the sanofi-aventis Group announced today that the European Commission has approved Taxotere (docetaxel) Injection Concentrate for use in combination with prednisone as a treatment for men with androgen-independent (hormone- refractory) metastatic prostate cancer.

4 Nov 2004

Wyeth shows new Phase III data about its investigational antibiotic, tigecycline

Wyeth Pharmaceuticals recently presented exciting new Phase III data about its investigational antibiotic, tigecycline, based on a clinical trial in patients with complicated intra-abdominal infections (cIAI).

4 Nov 2004

Peripheral blood transplants from donors may be more harmful than bone marrow transplants in pediatric leukemia patients

A new study has shown for the first time that transplantation of peripheral blood stem cells (PBSC) from sibling donors may be more harmful than bone marrow in pediatric leukemia patients.

3 Nov 2004

Analysis shows Remicade reduces pain associated with Crohn's disease

According to a new sub-analysis from the ACCENT I (A Crohn's disease Clinical trial Evaluating infliximab in a New long-term Treatment regimen) trial patients who received a three-dose induction regimen of Remicade experienced a significantly greater reduction in pain as assessed by four different pain questions after ten weeks, compared with patients who received a single dose of Remicade.

2 Nov 2004

Maxim Pharmaceuticals to withdraw NDA for advanced malignant melanoma

Maxim Pharmaceuticals has announced that based upon the negative outcome of it's confirmatory Phase 3 clinical trial (M0104) studying Ceplene(TM) (histamine dihydrochloride) in combination with Interleukin-2 (IL-2) in advanced malignant melanoma patients with liver metastases, it plans to close the treatment protocol approved by the FDA earlier this year.

2 Nov 2004

High-dose statin therapy for aggressive cholesterol-lowering outperforms typical care

Patients treated with high doses of atorvastatin had about a one percent lower annual rate of heart attacks than similar patients receiving usual care, according to a new study in the Nov. 2, 2004 issue of the Journal of the American College of Cardiology.

2 Nov 2004

Possible treatment for the fatal lung disease idiopathic pulmonary fibrosis

They found that the anti-cancer drug imatinib mesylate — commercially known as Gleevec and produced by Novartis Pharmaceuticals — can target a gene critical to controlling the disease process. Previously, there had been no treatment and patients usually did not survive beyond three years of diagnosis. Now the treatment is undergoing clinical trials at Mayo Clinic.

2 Nov 2004

Clinical trial of investigational oxygen-carrying blood substitute for use at the scene of injury

Loyola University Health System begins today the national clinical trial using PolyHeme®, an investigational oxygen-carrying blood substitute designed to increase survival of critically injured and bleeding trauma patients at the scene of injury.

1 Nov 2004

Improved risk classification for patients with acute lymphoblastic leukemia offers hope for eliminating irradiation

Improved risk classification for patients with acute lymphoblastic leukemia (ALL), coupled with more intensive intrathecal chemotherapy for high risk patients and the use of a drug called dexamethasone, could one day permit physicians to omit irradiation as a part of routine treatment.

1 Nov 2004

New approaches for the treatment of chronic hepatitis C

Data from two ongoing studies testing new approaches for the treatment of chronic hepatitis C was presented at the annual meeting of the American Association for the Study of Liver Diseases (AASLD) this afternoon.

1 Nov 2004

New treatment option for patients who have moderately active ulcerative colitis

Results of a study presented today by a Mayo Clinic physician at the 69th Annual Scientific Meeting of the American College of Gastroenterology (ACG) in Orlando, Fla., offer a new treatment option for patients who have moderately active ulcerative colitis.

1 Nov 2004

Brain imaging technology shows how the adult dyslexic brain can change

New findings from researchers at Georgetown University Medical Center in collaboration with Wake Forest University School of Medicine have shown that there is hope for individuals suffering a life-long history of reading problems.

1 Nov 2004

Alimta approved as first treatment for Mesothelioma, a deadly cancer caused by asbestos

Lilly UK announced today that Alimta( (pemetrexed) will be available shortly for the treatment of people diagnosed with mesothelioma, a cancer of the lining of the lungs for which there is no known cure. Pemetrexed is the first licenced treatment for malignant pleural mesothelioma, in combination with cisplatin.

1 Nov 2004

Brief psychological interventions are effective in relieving traumatic stress symptoms in family members

Family therapy and other psychological treatments may help reduce symptoms of post-traumatic stress among teenaged survivors of childhood cancer--as well as among their parents.

28 Oct 2004

Clinical Trial News and Research

Women who have diets rich in oils containing alpha-linolenic appear to have a lower risk of dying from heart disease

New valve repair device that could replace major heart surgery

Major bone trial to test high dose corticosteroid steroid tablets

Link between immune protein and longer survival in melanoma patients

Trial of new type of drug that attacks amyloid

Psoriasis trial enters final stage

European approval for Taxotere (docetaxel) in prostate cancer

Wyeth shows new Phase III data about its investigational antibiotic, tigecycline

Peripheral blood transplants from donors may be more harmful than bone marrow transplants in pediatric leukemia patients

Analysis shows Remicade reduces pain associated with Crohn's disease

Maxim Pharmaceuticals to withdraw NDA for advanced malignant melanoma

High-dose statin therapy for aggressive cholesterol-lowering outperforms typical care

Possible treatment for the fatal lung disease idiopathic pulmonary fibrosis

Clinical trial of investigational oxygen-carrying blood substitute for use at the scene of injury

Improved risk classification for patients with acute lymphoblastic leukemia offers hope for eliminating irradiation

New approaches for the treatment of chronic hepatitis C

New treatment option for patients who have moderately active ulcerative colitis

Brain imaging technology shows how the adult dyslexic brain can change

Alimta approved as first treatment for Mesothelioma, a deadly cancer caused by asbestos

Brief psychological interventions are effective in relieving traumatic stress symptoms in family members

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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