Mitochondria News and Research

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Study provides better understanding of how to treat individuals affected by copper imbalances

Copper is an essential part of our lives. From copper pipes and wires - to important copper-containing proteins in the body, copper is necessary for healthy growth and neurological development.

2 May 2007

Ultra fast and ultra active: the strange life of the extraocular muscles

The eye, often called the window to the soul, may become a window to the mysteries of muscular dystrophy, a debilitating muscle disease that often leads to death in early adulthood.

2 May 2007

Small amounts of stem/progenitor cells from bone marrow enhance repair of damaged tissues

New studies in the laboratory of Dr. Darwin J. Prockop, Director of Tulane University's Center for Gene Therapy, are shedding light on the previously mysterious mechanism through which even relatively small amounts of stem/progenitor cells taken from a patient's own bone marrow enhance repair of damaged tissues.

30 Apr 2007

Important new discovery in metabolomics

St. Jude investigators have mapped out many of the dynamic genetic and biochemical changes that make up a cell's response to a shortage of a molecule called Coenzyme A (CoA), a key player in metabolism.

27 Apr 2007

Moonlighting enzyme linked to Friedreich's ataxia

Friedreich's ataxia is one of those diseases few have heard of unless you know someone with the condition.

25 Apr 2007

Potential therapeutic target for multiple sclerosis

Oregon Health & Science University neuroscientists are eyeing a protein as a potential therapeutic target for multiple sclerosis because de-activating it protects nerve fibers from damage.

24 Apr 2007

Naturally occurring compound found in many fruits and vegetables as well as red wine, selectively kills leukemia cells

These findings, which were published online March 20 in the Journal of Biological Chemistry and will be in press on May 4, offer hope for a more selective, less toxic therapy for leukemia.

24 Apr 2007

Researchers identify key gene that may be a marker of breast cancer metastasis

Despite the fact that they both infect the liver, the hepatitis A and hepatitis C viruses actually have very little in common.

19 Apr 2007

Researchers find hepatitis A and hepatitis C attack same protein to block immune defenses

Despite the fact that they both infect the liver, the hepatitis A and hepatitis C viruses actually have very little in common.

19 Apr 2007

Researchers discover how cells fine-tune oxygen use

Researchers at Johns Hopkins have discovered how cells fine-tune their oxygen use to make do with whatever amount is available at the moment.

7 Apr 2007

Research shows potential for treatment of diabetics in hypoglycemic coma

Brain damage that was thought to be caused by hypoglycemic coma actually occurs when glucose is administered to treat the coma, according to a study in rodents led by researchers at the San Francisco VA Medical Center.

5 Apr 2007

Revving up a crucial set of muscle genes improves muscular dystrophy symptoms in mice

Scientists at Dana-Farber Cancer Institute have shown in a laboratory study that revving up a crucial set of muscle genes counteracts the damage caused by a form of muscular dystrophy.

2 Apr 2007

Hearing-protection tablet helps soldiers defend against hearing loss

Soldiers exposed to the deafening din of battle have little defense against hearing loss, and are often reluctant to wear protective gear like ear plugs that could make them less able to react to danger.

31 Mar 2007

Researchers look at whether creatine slows progression of Parkinson's disease

Researchers at the University of Rochester Medical Center are leading one of the largest clinical trials ever for Parkinson's disease.

25 Mar 2007

Creatine may help Parkinson's patients by giving an energy boost to dying cells

Whether a supplement used by athletes to boost energy levels and build muscle can slow progression of Parkinson's disease is the focus of a North American study.

22 Mar 2007

Study shows PanK2 enzyme within mitochondria is triggered by the first step in fatty acid breakdown

Just as homes have smoke detectors, cells have an enzyme that responds to a buildup of fatty acids by triggering the production of a key molecule in the biochemical pathway that breaks them down, according to investigators at St. Jude Children's Research Hospital. This provides the cell energy while reducing the chance that excess fatty acids will accumulate.

15 Feb 2007

Power-boosting signal in muscle declines with age

As people age, they may have to exercise even harder to get the benefits afforded to younger folk. That's the suggestion of a report in the February issue of the journal Cell Metabolism, showing that a signal that gives muscles a kind of metabolic boost in response to exercise is blunted in older animals.

6 Feb 2007

Antipodean Pharma commences phase 2 trial in hepatitis C

Antipodean Pharmaceuticals has announced it has initiated a Phase 2 clinical trial of its lead compound MitoQ (mitoquinone) to investigate the drug's efficacy to reduce liver damage in patients with raised liver enzymes associated with the Hepatitis C virus (HCV).

5 Feb 2007

Nanoparticles from crab shells show promise for drug delivery

Nanoparticles made of chitosan, a naturally occuring polymer isolated from crab and shrimp shells, have shown promise as carriers of anticancer drugs, antitumor genes, and other novel therapeutic agents.

22 Jan 2007