Congenital Heart Disease News and Research

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Study evaluates placental mesenchymal stem cell sheets for myocardial repair and regeneration

The placenta offers an abundant source of placenta-derived mesenchymal stem cells (pMSCs), which a new study has shown can readily form cell sheets that could be implanted in children with congenital heart defects and offer benefits for heart repair and regeneration compared to commonly used synthetic material-based scaffolds. Congenital heart disease is the leading cause of birth-defect-related illness and death.

9 Dec 2018

Miniature pacemakers aim to make heart procedures for infants less invasive, more efficient

At 2:15 p.m. C.T. on Sunday, Nov. 11, Rohan Kumthekar, M.D., a cardiology fellow working in Dr. Charles Berul's bioengineering lab at the Sheikh Zayed Institute for Pediatric Surgical Innovation, part of Children's National Health System, presents a prototype for a miniature pacemaker at the American Heart Association's Scientific Sessions 2018.

9 Nov 2018

AR may help cardiologists plan and perform complex medical interventions

Augmented reality, a technology that superimposes computer-generated information on a user's view of the real world, offers a new platform to help physicians better visualize complex medical data, particularly before and during medical procedures.

24 Oct 2018

Hispanic infants with congenital heart disease have worse outcomes, research finds

Hispanic infants with critical types of congenital heart disease have worse outcomes in their first year than do their non-Hispanic white counterparts, a difference largely driven by their mother's level of education and type of insurance coverage, according to new research in Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.

10 Oct 2018

Massively parallel single-nucleus RNA sequencing reveals insights into heart disease

Scientists using a powerful new technology that sequences RNA in 20,000 individual cell nuclei have uncovered new insights into biological events in heart disease.

9 Oct 2018

RNA sequencing method uncovers new insights into biological events in heart disease

Scientists using a powerful new technology that sequences RNA in 20,000 individual cell nuclei have uncovered new insights into biological events in heart disease.

5 Oct 2018

Researchers investigate ability of Masimo ORi to reduce time ICU patients experience hyperoxemia

Masimo announced today the findings of an abstract presented at the 2018 Congress of the French Society of Anesthesia and Resuscitation in Paris in which researchers at CHU Angers in France investigated the ability of Masimo ORi™ to help clinicians reduce the number of days ICU patients experience hyperoxemia while on mechanical ventilation.

1 Oct 2018

Mesoblast’s MPC therapy for children featured at symposium for congenital heart disease

Mesoblast Limited today announced that Mesoblast's proprietary allogeneic mesenchymal precursor cell heart failure product candidate MPC-150-IM for use in children with hypoplastic left heart syndrome was featured at the First Cardiac Regenerative Symposium for Congenital Heart Disease in Baltimore, Maryland on the weekend.

26 Sep 2018

Sleep apnea, congenital heart disease in hospitalized infants strongly associated with death

Infants often aren't screened for sleep apnea, but a new study suggests the disorder may be tied to an increased risk of death in infants with congenital heart disease.

17 Sep 2018

Kidneys of babies with congenital heart disease tend to be enlarged at birth

The hearts and brains of babies born with congenital heart disease are not the only organs affected by this common medical condition.

11 Sep 2018

Novel program offers new options for adult congenital heart patients

Experts at the Vanderbilt Heart and Vascular Institute are forging new ground in the development of a first-of-its-kind program aimed at adults with congenital heart disease.

29 Aug 2018

New rapid imaging protocol quickly and cheaply detects heart ailments for people in Peru

A newly developed rapid imaging protocol quickly and cheaply diagnosed heart ailments in patients in Peru, according to new research in Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.

29 Aug 2018

New study finds that pregnancy is safe for most women with heart disease

Is it safe for women with heart disease to become pregnant? Usually, according to ten-year results from the ROPAC registry reported in a late breaking science session today at ESC Congress 2018.

28 Aug 2018

Researchers investigate ability of Masimo Ori to show oxygenation trends during moderate hyperoxia

Masimo announced today the findings of a study recently published in Anesthesia & Analgesia in which researchers at the University of Groningen, the Netherlands, and Ghent University, Belgium, investigated the ability of Masimo ORi to show trends in oxygenation in the moderate hyperoxic region.

27 Aug 2018

Pregnant women with heart disease must give birth at 40 weeks gestation

Pregnant women with heart disease should give birth at no later than 40 weeks gestation. That is one of the recommendations in the 2018 European Society of Cardiology Guidelines for the management of cardiovascular diseases during pregnancy published online today in European Heart Journal, and on the ESC website.

25 Aug 2018

Scientists solve 60-year-old mystery of how thalidomide caused birth defects

More than 60 years after the drug thalidomide caused birth defects in thousands of children whose mothers took the drug while pregnant, scientists at Dana-Farber Cancer Institute have solved a mystery that has lingered ever since the dangers of the drug first became apparent: how did the drug produce such severe fetal harm?

2 Aug 2018

Scientists win NIH grant to study discrete subaortic stenosis

Scientists at Rice University, Texas Children's Hospital and Baylor College of Medicine have won a prestigious National Institutes of Health grant to study the dynamic processes and cellular players linked to discrete subaortic stenosis, a congenital heart disease.

27 Jun 2018

Researchers demonstrate feasibility of implanting micropacemaker in pericardial sac around the heart

Investigators at Children's Hospital Los Angeles and the University of Southern California have demonstrated the feasibility of implanting a micropacemaker system in the pericardial sac surrounding the heart -- a breakthrough that may open up new cardiac pacing options for children and adults.

26 Jun 2018

Study combines gene editing and stem cell technologies to predict person’s risk for heart disease

Scientists may now be able to predict whether carrying a specific genetic variant increases a person's risk for disease using gene editing and stem cell technologies, according to new research in the American Heart Association's journal Circulation.

18 Jun 2018

Gene editing technology predicts heart disease risk

Scientists could now use gene editing and stem cell technologies to predict whether carrying a specific gene variant increases the risk of heart disease.