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Music therapy is beneficial for patients with sickle cell disease

A new study from University Hospitals (UH) Connor Whole Health found patients with Sickle Cell Disease (SCD) who participated in music therapy learned new self-management skills and improved their ability to cope with pain.

18 Feb 2022

Drugs that increase fetal hemoglobin levels may help people with sickle cell disease

Sickle cell anemia is an inherited blood disorder where red blood cells become sickle/crescent shaped. It causes frequent infections, swelling in the hands and legs, pain, severe tiredness and delayed growth or puberty.

18 Feb 2022

Gut enzymes open a gateway to create universal blood-type donor organs

A study published in Science Translational Medicine performed at the Latner Thoracic Surgery Research Laboratories and UHN's Ajmera Transplant Centre has proved that it is possible to convert blood type safely in donor organs intended for transplantation.

16 Feb 2022

Study identifies a link between mortality of newborns on ECMO and red blood cell transfusion volume

Newborns in respiratory failure who require the life-sustaining support of ECMO also require transfusion of red blood cells. But a new study indicates that the higher volume of these oxygen-carrying blood cells the babies receive, the higher their mortality rate.

14 Feb 2022

Mechanical blood clot removal helps nearly half of stroke survivors to achieve good outcomes

Mechanical removal of blood clots reduced post-stroke disability in nearly half of "all-comer" real-world stroke patients in an international study, according to preliminary late-breaking science presented today at the American Stroke Association's International Stroke Conference 2022.

11 Feb 2022

The serious risks COVID-19 may pose during pregnancy

Researchers report on the potential for serious maternal illness or death during or following a pregnancy complicated by COVID-19.

9 Feb 2022

Study reveals role of a protein in healthy functioning of blood stem cells

A protein that masterminds the way DNA is wrapped within chromosomes has a major role in the healthy functioning of blood stem cells, which produce all blood cells in the body, according to a new study from researchers at Weill Cornell Medicine.

28 Jan 2022

Common member of the gut microbiome found to have specific preference for blood group A antigens

Researchers have discovered that a common member of the human gut microbiome has a specific preference for blood group A antigens.

10 Jan 2022

Engineering hairy cellulose nanocrystals to capture chemotherapy drugs

Millions of people around the globe are affected by cancer each year; more than 39% of men and women are diagnosed with cancer during their lifetime.

7 Jan 2022

New engineered nanomaterials help capture chemotherapy drugs to avoid tissue damage

Standard chemotherapies may efficiently kill cancer cells, but they also pose significant risks to healthy cells, resulting in secondary illness and a diminished quality of life for patients. To prevent the previously unavoidable damage, researchers, led by Penn State, have developed a new class of nanomaterials engineered to capture chemotherapy drugs before they interact with healthy tissue.

6 Jan 2022

Novel therapy found to be safe and well-tolerated in patients with bone marrow cancer

Mount Sinai physician-scientists have found that a novel therapy for the bone marrow cancer myelofibrosis is safe and well-tolerated and is associated with modest improvements in patients in a Phase 1b clinical trial.

12 Dec 2021

Circulating microbubbles for measuring oxygen levels

Blood carries vital oxygen through our circulation system to muscles and organs. Acoustic tools can create small bubbles in our blood, capable of changing in response to oxygen and signifying oxygen levels.

29 Nov 2021

Study uncovers mechanism for insensitivity to key antimalarial drug in new pathogen variant

Malaria is one of the most dangerous infectious diseases. The causative pathogens are microorganisms of the genus Plasmodium.

29 Nov 2021

Examining the effects of malaria parasites on global health

News-Medical speaks to Professor Kevin Baird about his lifelong research into malaria and how another malaria parasite, P. Vivax, is taking a toll on global health.

22 Nov 2021

Study reveals a previously unrecognized cause of vascular injury in type 2 diabetes

Altered function of the red blood cells leads to vascular damage in type 2 diabetes. Results from a new study in cells from patients with type 2 diabetes and mice show that this effect is caused by low levels of an important molecule in the red blood cells.

9 Nov 2021

Oral drug works just as well as conventional therapy for anemia in patients with kidney disease

Anemia is a common and sometimes debilitating problem among patients with chronic kidney disease (CKD). Anemia can occur when the kidneys become damaged, limiting the production of erythropoietin (EPO) -; a hormone that signals to the body to make red blood cells.

7 Nov 2021

Unexpected antibody discovery provides new insight into how the body responds to malaria infection

Malaria, a pathogen transmitted into blood by mosquitoes in tropical climates, is typically thought of as a blood and liver infection.

3 Nov 2021

Lehigh’s undergraduate students receive NIH Award for new sickle cell diagnostic device

Their tickets were booked. Their schedules were set. The students were finally going to test their product on real people. But in July, Sierra Leone's COVID-19 level spiked almost overnight, and Lehigh's Sickle Cell Anemia Diagnostic Device team lost yet another opportunity to conduct fieldwork.

1 Nov 2021

Red blood cells play a much larger role in the immune system than previously thought

New research has revealed that red blood cells function as critical immune sensors by binding cell-free DNA, called nucleic acid, present in the body's circulation during sepsis and COVID-19, and that this DNA-binding capability triggers their removal from circulation, driving inflammation and anemia during severe illness and playing a much larger role in the immune system than previously thought.

20 Oct 2021

Single-genome sequencing reveals malaria parasite genetics and evolution

Understanding how malaria parasites evolve after a human is bitten by an infected mosquito is very difficult. There can be billions of individual parasites in a patient's bloodstream and traditional genetic sequencing techniques can't identify the raw material for evolution: new mutations.

12 Oct 2021