Vasculature News and Research

RSS

COVID-19 can affect the retina

Now, a new study published in the journal EClinicalMedicine shows that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronavirus disease (COVID-19), targets the retina.

22 Sep 2020

World’s smallest optical ultrasound detector developed

Researchers at Helmholtz Zentrum München and the Technical University of Munich (TUM) have developed the world's smallest ultrasound detector. It is based on miniaturized photonic circuits on top of a silicon chip.

16 Sep 2020

International trial of blood thinners for COVID-19 treatment begins

These trials, known as ACTIV-4 Antithrombotics, are part of the three planned adaptive trials in this area of clinical research, included in the Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) initiative. They are expected to yield new data on the safety and efficacy of these drugs in the treatment of active and convalescent COVID-19 treatment.

13 Sep 2020

Researchers aim to improve digital thermal imaging as a tool for monitoring cancer

Thermal imaging has been available for decades to detect temperature differences on the skin that could signal breast cancer without exposing patients to radiation, although the method is not as reliable as mammography.

8 Sep 2020

Cancer cells reshape, destroy or integrate into blood vessels to spread

In laboratory studies, Johns Hopkins Kimmel Cancer Center and Johns Hopkins University researchers observed a key step in how cancer cells may spread from a primary tumor to a distant site within the body, a process known as metastasis.

1 Sep 2020

Scientists combine 3D bioprinting and computer modeling to study cancer metastasis in blood vessels

Lawrence Livermore National Laboratory scientists have paired 3D-printed, living human brain vasculature with advanced computational flow simulations to better understand tumor cell attachment to blood vessels, the first step in secondary tumor formation during cancer metastasis.

26 Aug 2020

Large animals with ailing livers can grow new organ in lymph nodes from their own hepatocytes

Hepatocytes -- the chief functional cells of the liver -- are natural regenerators, and the lymph nodes serve as a nurturing place where they can multiply.

24 Aug 2020

Researchers develop 3D imaging technique to visualize damaged lung tissue after severe COVID-19

Physicists at the University of Göttingen, together with pathologists and lung specialists at the Medical University of Hannover, have developed a three-dimensional imaging technique that enables high resolution and three-dimensional representation of damaged lung tissue following severe Covid-19.

21 Aug 2020

COVID-19 causes significant dilation of lung blood vessels, indicates study

A new pilot study from the Icahn School of Medicine at Mount Sinai suggests that COVID-19 is causing significant dilation of the blood vessels of the lung, specifically the capillaries.

21 Aug 2020

Immunothrombotic dysregulation is key marker of disease severity in COVID-19

In severe cases of COVID-19, the infection can lead to obstruction of the blood vessels in the lung, heart and kidneys. Ludwig-Maximilians-Universitaet (LMU) in Munich researchers have now shown that activated immune cells and blood platelets play a major role in these pathologies.

7 Aug 2020

Neutrolis announces development of first-in-class therapy to target NETs in COVID-19 patients

Neutrolis, a biotechnology company developing therapeutics that target neutrophils, the most abundant immune cells in the body, today announced the development of NTR-441, a first-in-class DNASE1L3 enzyme analog that has the potential to rapidly and systemically clear neutrophil extracellular traps for severe cases of COVID-19.

5 Aug 2020

Two-step targeting strategy can increase clinical translation of nanoparticle-based therapies

Therapy-loaded nanoparticles may be directed to the brain by functionalization with ligands targeting BBB-associated proteins.

27 Jul 2020

Common hypertension drugs do not increase risk of severe, fatal COVID-19 infection

A new Northwestern Medicine study in mice found a widely used class of drugs to treat patients with hypertension, cardiovascular disease and diabetic kidney disease - many of whom are elderly -- does not increase the risk of developing a severe and potentially fatal COVID-19 infection, as previously feared.

22 Jul 2020

Obesity and metabolic syndrome increase risk for severe influenza, COVID-19

Metabolic syndrome increases the risk of severe disease from viral infection, according to a review of the literature performed by a team of researchers from St. Jude Graduate School of Biomedical Sciences and the University of Tennessee Health Science Center, both in Memphis.

15 Jul 2020

Markers of vascular damage in COVID-19

A new study by researchers at Yale University and published on the preprint server medRxiv reports on the plasma levels of biomolecules that reflect vascular damage in COVID-19.

2 Jul 2020

PrecisionLife scientists identify 68 genes linked to severe COVID-19 risk

PrecisionLife’s unique AI platform has found 68 genes associated with risk of developing severe COVID-19 after analysis of the genomes of 929 patients from the UK Biobank who had a severe response to SARS-CoV-2.

26 Jun 2020

Repurposing immunosuppressants to manage COVID-19

It might seem paradoxical to suggest immunosuppression could play a role in managing COVID-19. The seemingly logical therapeutic option for this disease would be an antiviral.

18 Jun 2020

Severity of COVID-19 linked to heparanase activity and heparan sulfate levels

Researchers at Radboud University Medical Center in the Netherlands reported an increase of heparanase activity and heparan sulfate levels in the plasma of patients with coronavirus disease (COVID-19), which was also associated with the severity of the condition – suggesting, in turn, potential treatment utility of low molecular weight heparins. The paper is currently available on the medRxiv* preprint server.

16 Jun 2020

Researchers receive federal funding to rapidly repurpose FDA-approved drugs for COVID-19

Researchers at the University of Maryland School of Medicine will be partnering on an agreement funded by the federal government's Defense Advanced Research Projects Agency (DARPA) to rapidly test hundreds of drugs, approved and marketed for other conditions, to see whether any can be repurposed to prevent or treat COVID-19.