in vivo News and Research

RSS

Study examines efficacy of 3D printing, computer modeling to predict paravalvular leak in TAVR

A new study examines the effectiveness of 3D printing technology and computer modeling to predict paravalvular leak in patients undergoing transcatheter aortic valve replacement (TAVR). A common risk of TAVR is an ill-fitting valve which can lead to PVL.

27 Apr 2018

Researchers use CRISPR/Cas9 technique to turn off gene that regulates cholesterol levels in adult mice

Biomedical engineers at Duke University have used a CRISPR/Cas9 genetic engineering technique to turn off a gene that regulates cholesterol levels in adult mice, leading to reduced blood cholesterol levels and gene repression lasting for six months after a single treatment.

27 Apr 2018

Zika virus can be used for treating aggressive human central nervous system tumors, shows study

A Brazilian study published April 26 in the journal Cancer Research shows for the first time in vivo that Zika virus can be used as a tool to treat aggressive human central nervous system (CNS) tumors.

27 Apr 2018

Researchers target telomerase for killing NRAS-mutant melanoma cells

Targeting telomerase was effective at killing NRAS-mutant melanoma cells, and the impact was further enhanced when the strategy was paired with an inhibitor of mitochondrial function, according to study results by The Wistar Institute published in Oncogene.

26 Apr 2018

Bacteria enhance antifungal drug resistance in early childhood caries

Early childhood caries, a form of severe tooth decay affecting toddlers and preschoolers, can set children up for a lifetime of dental and health problems. The problem can be significant enough that surgery is the only effective way to treat it.

25 Apr 2018

Scientists clarify casual role of oxidative stress in metabolically abnormal and healthy obesities

Scientists at Osaka University clarified that deletion of adipose oxidative stress (Fat ROS) decreased lipid accumulation in the liver, clinically improving insulin resistance and inducing metabolically healthy obesity.

25 Apr 2018

Researchers discover genetic catalysts that accelerate evolution of antibiotic resistance in bacteria

Researchers at Oxford University have shown that it is possible to identify genetic catalysts that accelerate the evolution of antibiotic resistance in bacteria - and that this knowledge could be used to design treatments to stifle the development of resistance.

24 Apr 2018

Scientists illustrate role of novel chromosomal mutations in fosfomycin resistance

Researchers identified novel chromosomal mutations and described their role in the development of resistance of Escherichia coli (E. coli) to broad-spectrum antibiotic fosfomycin, according to research presented at the 28th European Congress of Clinical Microbiology and Infectious Diseases.

23 Apr 2018

New microscope reveals how cells behave in 3D and real time inside living organisms

Astronomers developed a "guide star" adaptive optics technique to obtain the most crystal-clear and precise telescopic images of distant galaxies, stars and planets. Now a team of scientists, led by Nobel laureate Eric Betzig, PhD, are borrowing the very same trick.

20 Apr 2018

Aziyo Biologics, BIOTRONIK enter into US co-distribution agreement

Aziyo Biologics, Inc., a fully integrated regenerative medicine company, today announced that it has entered into a US co-distribution agreement for its CanGaroo Bio Envelope with BIOTRONIK, Inc., a global leader in cardio- and endovascular medical technology.

19 Apr 2018

New computational framework accurately predicts drug-drug and drug-food interactions

A Korean research team from KAIST developed a computational framework, DeepDDI, that accurately predicts and generates 86 types of drug-drug and drug-food interactions as outputs of human-readable sentences, which allows in-depth understanding of the drug-drug and drug-food interactions.

18 Apr 2018

Researchers develop new method to study activity of inflammatory cells

The process that the body sets in motion in the event of inflammation is complex, but also impressive. The main role here is played by immune cells migrating from the blood into the tissue to fight the inflammation.

17 Apr 2018

New faster, streamlined method for bowel cancer detection and treatment

Researchers at the South Australian Health and Medical Research Institute (SAHMRI) and the University of Adelaide have discovered a faster, more cost-effective way to determine which DNA mutations cause human bowel cancer.

17 Apr 2018

Glucose metabolism is key to neural network development, finds study

A new study has found that glucose metabolism is critical for the development of neural networks in the brain.

13 Apr 2018

KU Cancer Center to present evidence supporting anti-cancer drug at AACR 2018

The University of Kansas Cancer Center will present preclinical evidence supporting Ciclopirox Prodrug (CPX-POM), an anti-cancer agent currently in Phase I clinical trials, at the American Association for Cancer Research 2018 Annual Meeting in Chicago. Ciclopirox Prodrug was discovered by researchers at The University of Kansas Cancer Center and KU's Institute for Advancing Medical Innovation.

12 Apr 2018

Researchers develop thin, flexible polymers to record activity more deeply in the brain

Science has yet to unravel a complete understanding of the brain and all its intricate workings. It's not for lack of effort.

11 Apr 2018

New collection of transgenic flies could accelerate biomedical discovery

For more than 100 years, the humble fruit fly has been used to understand fundamental biological processes and has been a crucial tool for rapid preclinical gene discovery for myriads of human diseases.

6 Apr 2018

Researchers discover potential new therapeutic target for Ewing sarcoma

The sarcoma research group of the Bellvitge Biomedical Research Institute, led by Dr. Òscar Martínez-Tirado, has identified a potential new therapeutic target for Ewing sarcoma, the second most frequent bone cancer in children and adolescents, and a tumor known by its aggressiveness and tendency to metastasize.

5 Apr 2018

Research reveals role of colon signaling pathway in development of IBD

The intestine encounters more foreign substances, and potential toxins, than other parts of the body, so it is not surprising that a healthy gut is maintained by the tight control of immune responses.

30 Mar 2018

Researchers measure whether transcranial direct current stimulation generates EFs in deep brain areas

A defining characteristic of stroke is the loss of motor control due to structural damage in specific brain areas. In fact, motor impairments (or deficits) are the number one complication after stroke.

27 Mar 2018

in vivo News and Research

Study examines efficacy of 3D printing, computer modeling to predict paravalvular leak in TAVR

Researchers use CRISPR/Cas9 technique to turn off gene that regulates cholesterol levels in adult mice

Zika virus can be used for treating aggressive human central nervous system tumors, shows study

Researchers target telomerase for killing NRAS-mutant melanoma cells

Bacteria enhance antifungal drug resistance in early childhood caries

Scientists clarify casual role of oxidative stress in metabolically abnormal and healthy obesities

Researchers discover genetic catalysts that accelerate evolution of antibiotic resistance in bacteria

Scientists illustrate role of novel chromosomal mutations in fosfomycin resistance

New microscope reveals how cells behave in 3D and real time inside living organisms

Aziyo Biologics, BIOTRONIK enter into US co-distribution agreement

New computational framework accurately predicts drug-drug and drug-food interactions

Researchers develop new method to study activity of inflammatory cells

New faster, streamlined method for bowel cancer detection and treatment

Glucose metabolism is key to neural network development, finds study

KU Cancer Center to present evidence supporting anti-cancer drug at AACR 2018

Researchers develop thin, flexible polymers to record activity more deeply in the brain

New collection of transgenic flies could accelerate biomedical discovery

Researchers discover potential new therapeutic target for Ewing sarcoma

Research reveals role of colon signaling pathway in development of IBD

Researchers measure whether transcranial direct current stimulation generates EFs in deep brain areas

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Latest News