in vivo News and Research

RSS

Cell-penetrating 'nanodrills' could be new platform for intracellular drug delivery

Researchers at Oregon State University and Oregon Health & Science University have created new nanomaterials able to cross cell membranes, establishing a novel platform for the intracellular delivery of molecular drugs and other cargo.

27 Mar 2018

Scientists use CRISPR to develop a genome surveillance tool

Scientists have converted CRISPR/Cas9 into a genome surveillance tool, in an effort to develop a more effective way of fighting disease.

27 Mar 2018

Changing schedules of targeted therapy for melanoma could improve outcomes

Skin melanoma, a particularly insidious cancer, accounts for the vast majority skin cancer deaths and is one of the most common cancers in people under 30.

26 Mar 2018

Scientists create synthesized antibiotic capable of treating superbugs

A "game changing" new antibiotic which is capable of killing superbugs has been successfully synthesized and used to treat an infection for the first time -- and could lead to the first new class of antibiotic drug in 30 years.

23 Mar 2018

Research offers new understanding about cause of Parkinson's disease

Until very recently, Parkinson's had been thought a disease that starts in the brain, destroying motion centers and resulting in tremors and loss of movement.

21 Mar 2018

Targeting aberrantly active telomerase to treat therapy-resistant melanoma

A study conducted at The Wistar Institute in collaboration with The University of Texas Southwestern Medical Center has demonstrated the efficacy of targeting aberrantly active telomerase to treat therapy-resistant melanoma.

21 Mar 2018

Researchers succeed in integrating artificial organelles into cells of living organism

For the first time, an interdisciplinary team from the University of Basel has succeeded in integrating artificial organelles into the cells of living zebrafish embryos.

20 Mar 2018

American Gene Technologies receives second immuno-oncology patent

American Gene Technologies International Inc., a leading gene and cell therapy company, today announced receipt of a second immuno-oncology patent on the stimulation of gamma delta T cells for treating solid tumors in epithelial cancers.

20 Mar 2018

Speeding up wound healing using nanofiber dressings

Scientists have developed two new types of wound dressing that dramatically increase healing rates and improve tissue regeneration.

19 Mar 2018

Blood flow defies the laws of fluid dynamics

Researchers have developed a 3D simulation of blood cells travelling through realistic microvascular networks that has predicted several novel phenomena.

16 Mar 2018

Study reveals mechanisms underlying maintenance of memory during sleep hours

During the hours of sleep the memory performs a cleaning shift. A study led by a Spanish scientist at the University of Cambridge reveals that when we sleep, the neural connections that collect important information are strengthened and those created from irrelevant data are weakened until they get lost.

15 Mar 2018

Innovnano and FCT-NOVA team up to produce synthetic bone material

Innovnano, an expert manufacturer of structural zirconia ceramics, has entered into an R&D project with Universidade NOVA de Lisboa to produce zirconia-based ceramic orthopedic implants by 3D printing.

14 Mar 2018

Toothpastes alone cannot protect against dental erosion and hypersensitivity

The rising prevalence of dental erosion and dentin hypersensitivity has led to the emergence of more and more toothpastes on the market that claim to treat these problems. While no such toothpaste existed 20 years ago, today, many brands with different attributes are being offered.

14 Mar 2018

Korean scientists track growth, migration of cells under hypoxic conditions using xCELLigence RTCA

Tracking the growth and migration of cells under hypoxic conditions in vitro can be challenging because measurements must be made in a manner that does not perturb the atmospheric composition of the closed system.

13 Mar 2018

ACEA Biosciences develops novel assay for rapid identification of endocrine-disrupting chemicals

Endocrine-disrupting chemicals are substances that interfere with the ability of endogenous hormones to regulate homeostasis via their cognate nuclear receptors.

13 Mar 2018

Slow-release injectable gel boosts toxicity of cancer-fighting immunotherapy drugs

An immunotherapy drug embedded in a slow-release hydrogel invented at Rice University in collaboration with the University of Texas Health Science Center at Houston appears to be highly effective at killing cancer cells.

7 Mar 2018

Corin unveils new Trinity Dual Mobility System for hip replacement at AAOS Annual Meeting

Corin, a global orthopedic manufacturer and leader in functional implant positioning, today announced the launch of the Trinity Dual Mobility System featuring new implant technology designed to improve range of motion and reduce the risk for instability and dislocation after primary or revision hip replacement.

7 Mar 2018

New study shows advantages of DNA barcoding technique for identifying nanoparticles

The first direct comparison of in vitro and in vivo screening techniques for identifying nanoparticles that may be used to transport therapeutic molecules into cells shows that testing in lab dishes isn't much help in predicting which nanoparticles will successfully enter the cells of living animals.

5 Mar 2018

Research reveals how mutant p53 enhances tumor metastasis

Scientists at The Wistar Institute have found a novel mechanism through which mutant p53 enhances metastasis by controlling tumor metabolism. The research, published online in Genes & Development, also revealed how this process is influenced by a naturally occurring p53 gene variant.

26 Feb 2018

Schizophrenia may be related to neurodevelopment changes, study says

Schizophrenia may be related to neurodevelopment changes, including brain's inability to create the appropriate vascular system, according to new study resulted from a partnership between the D'Or Institute for Research and Education, the University of Chile and the Federal University of Rio de Janeiro.

22 Feb 2018