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Biotechnology startup receives FDA clearance for synthetic bone graft substitute

A biotechnology startup enabled by UC Davis, Molecular Matrix Inc., has received Food and Drug Administration clearance for a carbohydrate-based polymer that can help injured bones heal and regrow.

27 Jan 2018

Repurposed drug effectively protects against Zika virus in mouse models

In both cell cultures and mouse models, a drug used to treat Hepatitis C effectively protected and rescued neural cells infected by the Zika virus -- and blocked transmission of the virus to mouse fetuses.

25 Jan 2018

Fluorescence imaging can track vitamin C in the body

Vitamin C is best known as a nutrient. In high enough doses, however, vitamin C also shows potential against many cancers, according to recent studies. To successfully develop vitamin C (chemically named ascorbic acid) as a medication, it is crucial to probe its concentration in the body, thus ensuring safe and effective doses.

24 Jan 2018

Discovery may advance stem cell therapies, gene-targeting treatments for neurological diseases

New research from Sanford Burnham Prebys Medical Discovery Institute is among the first to describe how an mRNA modification impacts the life of neural stem cells.

24 Jan 2018

Scientists imitate the Human Blood-retinal barrier on a microfluidic chip

For years scientists have sought to minimise Animal testing and speed up clinical trials. One alternative is the use of in vitro assays using live cells, but its effectiveness is limited, since it is difficult to reproduce interaction and interconnection between cells.

24 Jan 2018

Enzyme inhibitor and chemotherapy combination regresses glioblastoma

In animal experiments, a human-derived glioblastoma significantly regressed when treated with the combination of an experimental enzyme inhibitor and the standard glioblastoma chemotherapy drug, temozolomide.

24 Jan 2018

BIST researchers develop new retinal prosthesis to address visual degeneration

A healthy retina contains photoreceptor cells that convert light changes into nerve impulses, which are then carried along the optic nerve to the brain, where they are decoded into images. Diseases such as retinitis pigmentosa cause the photoreceptor cells to stop functioning, while the rest of the eye remains healthy.

24 Jan 2018

Research shows how Zika virus damages placenta to cause malformations in babies

Though the Zika virus is widely known for a recent outbreak that caused children to be born with microencephaly, or having a small head, and other malformations, scientists have struggled to explain how the virus affects a baby as it grows in the womb.

19 Jan 2018

Researchers unravel key molecular mechanism of autoimmune and inflammatory diseases

An international team of researchers led by prof. Savvas Savvides has unraveled a crucial aspect of the molecular basis of autoimmune and inflammatory diseases such as psoriasis, rheumatoid arthritis and Crohn's disease.

18 Jan 2018

Findings reveal conventional cancer therapy as double-edged sword

Researchers have discovered that killing cancer cells can actually have the unintended effect of fueling the proliferation of residual, living cancer cells, ultimately leading to aggressive tumor progression.

18 Jan 2018

Maximize resolution in deep imaging for neuroscience research with Olympus TruResolution objectives

Two new Olympus TruResolution objectives for multiphoton laser scanning microscopes deliver an industry-first automatic spherical aberration compensation function that also compensates for Z-shifts when operating the correction collar. This function automatically finds the best collar setting based on measured image contrast for clear, bright imaging.

From Evident Corporation - Life Sciences 18 Jan 2018

Researchers identify new anti-inflammatory drug target

A new study suggests that parmodulins may provide anti-inflammatory and anti-thrombotic protection to endothelial cells, without interfering with clotting.

16 Jan 2018

Novel antifungal shows promise to stave off drug-resistant superbugs

Microscopic yeast have been wreaking havoc in hospitals around the world- creeping into catheters, ventilator tubes, and IV lines- and causing deadly invasive infection.

11 Jan 2018

Radiation therapy algorithm could lessen side effects, maintain effectiveness of treatment

Researchers at North Carolina State University have developed a mathematical model for computing radiation therapy treatments that could substantially reduce patient side effects while delivering the same results as conventional radiation therapy.

5 Jan 2018

Macrophage nanosponges offer promising solution for effectively managing sepsis

A team of researchers at the University of California San Diego has developed macrophage "nanosponges" that can safely absorb and remove molecules from the bloodstream that are known to trigger sepsis.

4 Jan 2018

Researchers grow hairy skin using mouse stem cells

Indiana University School of Medicine researchers have cultured the first lab-grown skin tissue complete with hair follicles.

3 Jan 2018

Bioengineers reveal how to recreate complex folded shapes from living tissue

Many of the complex folded shapes that form mammalian tissues can be recreated with very simple instructions, UC San Francisco bioengineers report December 28 in the journal Developmental Cell.

30 Dec 2017

FDA-approved drug to treat high blood pressure increases life span in worms

UT Southwestern Medical Center researchers find that an FDA-approved drug to treat high blood pressure seems to extend lifespan in worms via a cell signaling pathway that may mimic caloric restriction.

21 Dec 2017

Nanomedicine platform can guide doctors to remove tumors and kill malignant cells

Oregon State University scientists have developed a nanomedicine platform for cancer that can help doctors know which tissue to cut out as well as kill any malignant cells that can't be surgically removed.

21 Dec 2017

Study finds combination therapy as effective strategy to treat ovarian cancers

Researchers at The Wistar Institute have found that combining PARP inhibitors, recently approved for the treatment of BRCA-mutant ovarian cancer, with another small molecule inhibitor was effective to treat ovarian cancers without BRCA1 and BRCA2 gene mutations.

19 Dec 2017