Neurodegenerative Diseases News and Research

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Leaky blood vessels open up nerve cells to toxic assault In Lou Gehrig's disease

Leaky blood vessels that lose their ability to protect the spinal cord from toxins may play a role in the development of amyotrophic lateral sclerosis, better known as ALS or Lou Gehrig's disease, according to research published in the April issue of Nature Neuroscience.

7 Apr 2008

New blood test gives early diagnosis of neurodegenerative diseases

A new blood test that can give an early diagnosis of neurodegenerative disease and distinguish between Parkinson's and Alzheimer's disease could be launched this summer, reports Marina Murphy in SCI's Chemistry & Industry magazine.

7 Apr 2008

Discovery of novel gene responsible for Lou Gehrig's disease

A team of Canadian and French researchers has identified a novel gene responsible for a significant fraction of ALS (sporadic amyotrophic lateral sclerosis) cases.

1 Apr 2008

Insulin-like growth factor found to have new role in development of brain's smell center

A human hormone known to stimulate the growth of cells throughout the body has a new role - helping to set up the proper nerve connections in the odor center of the brain, according to University of California, Berkeley, scientists.

28 Mar 2008

Worm defecation holds clues to widespread cell-to-cell communication process

The focus of two recent Nobel prizes, a species of roundworm has made possible another advance in the understanding of how cells talk to one another, according to a study published online Feb. 21 in the journal Current Biology.

22 Feb 2008

Genetic defect causes immune deficiency and balance disorder

A genetic defect that causes a severe immune deficiency in humans may also produce balance disorders, according to a new study by researchers at the University of Iowa, The Jackson Laboratory and East Carolina University.

21 Feb 2008

Prion infection of neurons increases the free cholesterol content in cell membranes

A new study published in the online open access journal BMC Biology suggests that disturbances in membrane cholesterol may be the mechanism by which prions cause neurodegeneration and could point to a role for cholesterol in other neurodegenerative diseases.

12 Feb 2008

New insight into how iron gets deposited in the brain to cause some forms of Parkinson's and Alzheimer's

Researchers at the University of Warwick and the Indian Institute of Technology Kanpur have discovered that the mechanism that we rely on to transport iron safely through our blood stream can, in certain circumstances, collapse into a state which grows long worm-like "fibrils" banded by lines of iron rust.

11 Feb 2008

RNA-associated introns guide nerve-cell channel production

Researchers at the University of Pennsylvania School of Medicine have discovered that introns, or junk DNA to some, associated with RNA are an important molecular guide to making nerve-cell electrical channels.

7 Feb 2008

New understanding of cancer initiation

Researchers at the University of Nebraska Medical Center (UNMC) in Omaha have assisted in a significant discovery - the understanding of a common mechanism of cancer initiation - that could result in better cancer assessment, prevention and detection.

7 Feb 2008

Structure of important neurotransmitter regulator solved

Researchers from Virginia Tech and the Brookhaven National Laboratory have solved the structure of an enzyme that is critical in the regulation of the neurotransmitter system in the human brain.

4 Feb 2008

Fruit for Alzheimer's

...

4 Feb 2008

Neurogenesis plays an important role in the acquisition and storage of spatial memory

Boosted by physical and mental exercise, neural stem cells continue to sprout new neurons throughout life, but the exact function of these newcomers has been the topic of much debate.

4 Feb 2008

Unexpected protein-protein interaction suggests new ALS drug target

Discovery of an unexpected protein-protein interaction has led University of Iowa scientists and colleagues to identify a drug that slows the progression of Amyotrophic Lateral Sclerosis (ALS) in mice and nearly doubles the animals' lifespan.

25 Jan 2008

New MIT tool probes brain circuits

Researchers at the Picower Institute for Learning and Memory at MIT report in the Jan. 24 online edition of Science that they have created a way to see, for the first time, the effect of blocking and unblocking a single neural circuit in a living animal.

25 Jan 2008

Alzheimer's molecule is a smart speed bump on the nerve-cell transport highway

Researchers at the University of Pennsylvania School of Medicine discovered that proteins carrying chemical cargo in nerve cells react differently when exposed to the tau protein, which plays an important role in Alzheimer's disease.

18 Jan 2008

New clue found to the cause of Parkinson's disease

A glitch in the mechanism by which cells recycle damaged components may trigger Parkinson's disease, according to a study by scientists at the Albert Einstein College of Medicine of Yeshiva University.

3 Jan 2008

Overexcited neurons not good for cell health

Neurotransmitters have consequences. They initiate events that are critical to a healthy life, giving us the ability to move, to talk, to breathe, to think. But that's if the neurotransmitters are getting it right and sending proper signals downstream to muscle cells, neurons or other cells.

18 Dec 2007

Aging gracefully requires taking out the trash

Suppressing a cellular cleanup-mechanism known as autophagy can accelerate the accumulation of protein aggregates that leads to neural degeneration.

17 Dec 2007

Immune system may target some brain synapses

A baby's brain has a lot of work to do, growing more neurons and connections.

14 Dec 2007

Neurodegenerative Diseases News and Research

Leaky blood vessels open up nerve cells to toxic assault In Lou Gehrig's disease

New blood test gives early diagnosis of neurodegenerative diseases

Discovery of novel gene responsible for Lou Gehrig's disease

Insulin-like growth factor found to have new role in development of brain's smell center

Worm defecation holds clues to widespread cell-to-cell communication process

Genetic defect causes immune deficiency and balance disorder

Prion infection of neurons increases the free cholesterol content in cell membranes

New insight into how iron gets deposited in the brain to cause some forms of Parkinson's and Alzheimer's

RNA-associated introns guide nerve-cell channel production

New understanding of cancer initiation

Structure of important neurotransmitter regulator solved

Fruit for Alzheimer's

Neurogenesis plays an important role in the acquisition and storage of spatial memory

Unexpected protein-protein interaction suggests new ALS drug target

New MIT tool probes brain circuits

Alzheimer's molecule is a smart speed bump on the nerve-cell transport highway

New clue found to the cause of Parkinson's disease

Overexcited neurons not good for cell health

Aging gracefully requires taking out the trash

Immune system may target some brain synapses

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